scholarly journals Autoimmune Progesterone Dermatitis: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-2 ◽  
Author(s):  
Rachana George ◽  
Shawky Z. A. Badawy
Keyword(s):  
Case Report ◽  
Oral Contraceptive ◽  
Erythema Multiforme ◽  
Luteal Phase ◽  
Typical Case ◽  
Systemic Diseases ◽  
Oral Contraceptive Pills ◽  
Progesterone Secretion ◽  
Contraceptive Pills ◽  
One Year

Background. Autoimmune progesterone dermatitis is a rare cyclic premenstrual allergic reaction to progesterone produced during the luteal phase of a woman's menstrual cycle. Patients present with a variety of conditions including erythema multiforme, eczema, urticaria, angioedema, and progesterone-induced anaphylaxis.Case. Thirty-eight-year-old woman G2P2002 presents with erythema multiforme and urticarial rash one week prior to her menses starting one year after menarche. She was treated with oral contraceptive pills and the symptoms resolved.Conclusion. This is a typical case of progesterone autoimmunity. The diagnosis is based on cyclic nature of the dermatitis. This differentiates the condition from other allergies or systemic diseases with skin manifestations. Inhibition of ovulation in such cases results in decrease in progesterone secretion and prevention of symptoms.

scholarly journals The Effect of Oral Contraceptive Pills on The Macula, the Retinal Nerve Fiber Layer, The Ganglion Cell Layer and The Choroidal Thickness

2019 ◽  
Author(s):  
Yasmine Maher Shaaban ◽  
Tamer Abdel-Fattah Badran
Keyword(s):  
Oral Contraceptive ◽  
Nerve Fiber ◽  
Choroidal Thickness ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Control Group ◽  
Fiber Layer ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
One Year

Abstract Background To evaluate the effect of oral contraceptive pills (OCP) on the macula, the retinal nerve fiber layer (RNFL), the ganglion cell layer ( GCL), and the choroidal thickness (CT). Methods In this prospective observational cross-sectional study, 60 eyes of 30 healthy women taking mono phasic OCP (0.03 mg ethinylestradiol and 0.15 mg levonorgestrel) for contraception for at least one year were compared with 60 eyes of a control group of 30 healthy women who were not taking any OCP. Spectral-Domain Optical Coherence Tomography (SD-OCT) was used to evaluate the macula, the RNFL, the GCL, and the CT. Measurements were taken in the follicular phase (day 3) of the last menstrual cycle in all women. The body mass index (BMI) scores of all participants were also recorded. Results No disparity in terms of age and BMI between both groups was observed (p=0.444, p=0.074, respectively). All the macular parameters measurements were considerably lower in the OCP group compared to the control group (p<0.001). Also, the RNFL thickness, the GCL thickness, and the CT were all significantly thinner in the OCP group (p<0.001). Conclusions The use of OCP can cause significant changes in the retina and choroid thickness over one year period. The women who are using OCP for a longer duration could have some eye problems. OCT should be routinely done for follow up. Further long term studies are required, using different preparations of OCP. It is important to find out when this thickness alterations can be clinically significant or symptomatic and if these changes are reversible or not. Keywords Oral Contraceptive, Macula, Nerve fiber, Ganglion, Choroid, Ocular Coherence Tomography.

scholarly journals The Effect of Oral Contraceptive Pills on the Macula, the Retinal Nerve Fiber Layer, The Ganglion Cell layer and The Choroidal Thickness

2019 ◽  
Author(s):  
Yasmine Maher Shaaban ◽  
Tamer Abdel-Fattah Badran
Keyword(s):  
Oral Contraceptive ◽  
Ganglion Cell ◽  
Choroidal Thickness ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Control Group ◽  
Fiber Layer ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
One Year

Abstract Background To evaluate the effect of oral contraceptive pills (OCP) on the macula, the retinal nerve fiber layer (RNFL), the ganglion cell layer ( GCL), and the choroidal thickness (CT). Methods In this prospective observational cross-sectional study, 60 eyes of 30 healthy women taking monophasic OCP (0.03 mg ethinylestradiol and 0.15 mg levonorgestrel) for contraception for at least one year were compared with 60 eyes of a control group of 30 healthy women who were not taking any OCP. Spectral Domain Optical Coherence Tomography (SD-OCT) was used to evaluate the macula, the RNFL, the GCL, and the CT. Measurements were taken in the follicular phase (day 3) of the last menstrual cycle in all women. Results No disparity in terms of age between both groups was observed (p=0.444). All the macular parameters measurements were considerably lower in the OCP group compared to the control group (p<0.001). Also, the RNFL thickness, the GCL thickness, and the CT were all significantly thinner in the OCP group (p<0.001). Conclusions The use of OCP can cause significant changes in the retina and choroid thickness over one year period. The women who are using OCP for longer duration could have some eye problems. OCT should be routinely done for follow up. Further long term studies are required, using different preparations of OCP. It is important to find out when this thickness alterations can be clinically significant or symptomatic and if these changes are reversible or not.

scholarly journals From an Incidental Finding to an Emergent Treatment: A Case Report of a Hepatic Adenomatosis and Large Ruptured Hepatic Adenoma

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Maria Mironova ◽  
Mohammed K. Mahdi ◽  
Jyoti Bhatia ◽  
Rosemarie C. Nielson ◽  
Cataldo Doria
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Oral Contraceptive ◽  
Malignant Transformation ◽  
Hepatic Adenoma ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Risk Of Rupture ◽  
Prevalence Of Obesity ◽  
Hepatic Adenomatosis

Introduction. Hepatic adenoma is an uncommon benign liver tumor presenting as solitary lesions or even rarely as hepatic adenomatosis. Large lesions carry a risk of rupture, hemorrhage, and malignant transformation. This case report aims to increase awareness about risk factors for hepatic adenomas, considering the increasing prevalence of obesity and the widespread use of oral contraceptive pills. Case Presentation. A 20-year-old obese female who was taking oral contraceptive pills for seven years presented to the emergency department with vomiting and abdominal pain caused by gastroenteritis. On imaging, multiple hepatic adenomas, including two lesions 6 and 9 cm in diameter, were incidentally found. During the hospitalization, the patient suddenly developed acute anemia and rupture of the largest lesion, which was promptly treated with arterial embolization. Discussion. Obesity and exposure to hormones are well-known risk factors for hepatic adenomas. The incidence of hepatic adenomas is steadily increasing because of the prevalence of obesity, especially among females. Lifestyle interventions for weight loss and discontinuation of oral contraceptive pills are considered a conservative treatment of hepatic adenomas. Large lesions possess the risk of malignant transformation and rupture and require surgical excision.

scholarly journals The Effect of Oral Contraceptive Pills on the Macula, the Retinal Nerve Fiber Layer, The Ganglion Cell layer and The Choroidal Thickness

2019 ◽  
Author(s):  
Yasmine Maher Shaaban ◽  
Tamer Abdel-Fattah Badran
Keyword(s):  
Oral Contraceptive ◽  
Nerve Fiber ◽  
Choroidal Thickness ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Control Group ◽  
Fiber Layer ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
One Year

Abstract p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; text-align: justify; font: 10.0px 'Times New Roman'} p.p2 {margin: 0.0px 0.0px 6.0px 0.0px; text-align: justify; font: 10.0px 'Times New Roman'} p.p3 {margin: 0.0px 0.0px 12.0px 0.0px; text-align: justify; font: 10.0px 'Times New Roman'} span.s1 {letter-spacing: 0.0px} AbstractBackground To evaluate the effect of oral contraceptive pills (OCP) on the macula, the retinal nerve fiber layer (RNFL), the ganglion cell layer ( GCL), and the choroidal thickness (CT).Methods In this prospective observational cross-sectional study, 60 eyes of 30 healthy women taking monophasic OCP (0.03 mg ethinylestradiol and 0.15 mg levonorgestrel) for contraception for at least one year were compared with 60 eyes of a control group of 30 healthy women who were not taking any OCP. Spectral-Domain Optical Coherence Tomography (SD-OCT) was used to evaluate the macula, the RNFL, the GCL, and the CT. Measurements were taken in the follicular phase (day 3) of the last menstrual cycle in all women. The body mass index (BMI) scores of all participants were also recorded.Results No disparity in terms of age and BMI between both groups was observed (p=0.444, p=0.074, respectively). All the macular parameters measurements were considerably lower in the OCP group compared to the control group (p<0.001). Also, the RNFL thickness, the GCL thickness, and the CT were all significantly thinner in the OCP group (p<0.001).Conclusions The use of OCP can cause significant changes in the retina and choroid thickness over one year period. The women who are using OCP for a longer duration could have some eye problems. OCT should be routinely done for follow up. Further long term studies are required, using different preparations of OCP. It is important to find out when this thickness alterations can be clinically significant or symptomatic and if these changes are reversible or not.Keywords Oral Contraceptive, Macula, Nerve fiber, Ganglion, Choroid, Ocular Coherence Tomography.

Study the Relationship Between Estrogen Hormone and Calcium in Normal Females Before and After Menopause in Baghdad / Iraq

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Sameerah Mustafa ◽  
Asal Tawfeeq ◽  
Hadeel Hasan
Keyword(s):  
Oral Contraceptive ◽  
Healthy Controls ◽  
Serum Samples ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Menopausal Women ◽  
Before And After ◽  
Group A ◽  
Group B ◽  
Age Range

This study involved the collection of (90) samples of women serum which included (30) serum samples collected from women before menopause (reproductive women) in the age range of (22-43) years and were considered as (group A- control). While, (group B) included (30) serum samples collected from women using oral contraceptive pills between the ages of (22-43) years old. Whereas, another (30) serum samples were collected from women after menopause between the ages of (43-54) years and were considered as (group C). All of the collected serum samples were subjected to a number of serological and chemical tests for the measurement of (E2, HDL, LDL and Ca). Then, the obtained data were statistical analyzed and results showed a significant decrease (p˂ 0.05) in (E2 ,Ca and HDL) levels in menopausal women compared to that of the normal healthy controls. While, there were non-significant decrease (p> 0.05) in (E2, Ca and HDL) levels in women taking oral contraceptive when compared to the normal healthy controls. On the other hand, a significant increase (p˂ 0.05) was recorded in LDL level in menopausal women compared to that of the normal healthy controls whereas, no-significant increase (p˃ 0.05) in the LDL level in women taking oral contraceptives when compared to the control women.

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