scholarly journals MFH Mimic in Breast: A High-Grade Malignant Phyllodes Tumor

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
A. L. Hemalatha ◽  
V. Sumana Sindhuram ◽  
U. Asha

Malignant phyllodes tumor is usually diagnosed by the presence of benign duct-like epithelium and malignant mesenchymal tissue. In addition to the usual fibrosarcomatous features, the mesenchymal component may show areas resembling osteogenic sarcoma, chondrosarcoma, liposarcoma, leiomyosarcoma, rhabdomyosarcoma, malignant mesenchymoma, and, very rarely, malignant fibrous histiocytoma. We present one such rare case of malignant phyllodes tumor with malignant fibrous histiocytoma-like stromal differentiation.

1997 ◽  
Vol 58 (8) ◽  
pp. 1744-1747
Author(s):  
Ikuo KOKUFU ◽  
Masayuki YAMAMOTO ◽  
Yosuke AKIYAMA ◽  
Katsumi YAMADA ◽  
Hirofumi HIRAI ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Anastasios Katsourakis ◽  
George Noussios ◽  
Iosif Hadjis ◽  
Neofitos Evangelou ◽  
Efthimios Chatzitheoklitos

Malignant fibrous histiocytoma (MFH) of the small intestine is an extremely rare condition. It occurs most commonly in the extremities and the trunk. We report a case of a 67-year-old woman who admitted with fever, myalgia, and altered status. After thorough investigation, a tumor of the jejunum was found. The patient underwent complete surgical removal of the tumor. A diagnosis of MFN (undifferentiated high-grade pleomorphic sarcoma) was made. The patient received adjuvant chemotherapy with Gemcitabine. Two years after the operation, the patient died due to recurrence of the disease. MFH of the small intestine is an extremely rare neoplasm with an aggressive biological behaviour. In this paper, pathogenesis, natural history, and treatment are reviewed.


2017 ◽  
Vol 28 (3) ◽  
pp. e267-e269 ◽  
Author(s):  
Éder A. Sigua-Rodriguez ◽  
Douglas Rangel Goulart ◽  
Afonso Celso de Moraes Manzano ◽  
Luciana Asprino

1989 ◽  
Vol 31 (2) ◽  
pp. 177-179 ◽  
Author(s):  
B. Schrader ◽  
B. R. Holland ◽  
C. Friedrichsen

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Kimihisa Mizoguchi ◽  
Kazuhisa Kaneshiro ◽  
Makoto Kubo ◽  
Yoshihiko Sadakari ◽  
Yoshizo Kimura ◽  
...  

Abstract Background Granulocyte-colony stimulating factor (G-CSF)-producing tumors can cause leukocytosis despite an absence of infection. G-CSF-producing tumors have been reported in various organs such as the lung, esophagus, and stomach but rarely in the breast. We report a case of G-CSF-producing malignant phyllodes tumor of the breast. Case presentation An 84-year-old woman visited our hospital complaining of a lump in her left breast without fever and pain. Laboratory tests revealed elevated white blood cell (WBC) count and G-CSF levels. A malignant tumor of the breast was diagnosed by core needle biopsy. We performed a total mastectomy and sentinel lymph node biopsy. The tumor was identified as a G-CSF-producing malignant phyllodes tumor. Within 7 days after surgery, the patient’s WBC count and G-CSF level had decreased to normal levels. She is alive without recurrence 13 months after surgery. Conclusions We encountered a rare case of G-CSF-producing malignant phyllodes tumor of the breast. PET–CT revealed diffuse accumulation of FDG in the bone. Phyllodes tumors need to be differentiated from bone metastasis, lymphoma, and leukemia. We must be careful to not mistake this type of tumor for bone marrow metastasis.


2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Gabriel S. Makar ◽  
Michael Makar ◽  
Joanna Ghobrial ◽  
Kathryn Bush ◽  
Ryan Allen Gruner ◽  
...  

Primary breast neoplasms are rare in adolescent females, most of which are benign. Phyllodes tumors constitute a remarkably small subset of breast neoplasms (0.3-0.9%) with malignant phyllodes tumors being even more uncommon. Malignant phyllodes tumors tend to progress rapidly though only 1.5% metastasize. They are also associated with a higher rate of recurrence than their benign counterparts, underlying the importance of adequate surgical margins. It is therefore imperative to be able to identify these tumors early allowing for prompt resection and close follow-up. Here, we present the rare case of a 17-year-old female presenting with a rapidly enlarging breast mass, which was ultimately found to be a malignant phyllodes tumor. We further performed a review of the literature to highlight only 22 other cases reported in adolescent females.


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