Comparative Analysis of Normal versus Fetal Growth Restriction in Pregnancy: The Significance of Maternal Body Mass Index, Nutritional Status, Anemia, and Ultrasonography Screening

Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. The objective of this study was twofold: first to examine the correlation between maternal parameters such as body mass index (BMI), nutritional status, anemia, and placental weight and diameter, and their effects on fetal growth and then to evaluate the effect of early screening by ultrasonography (USG) on the outcome of growth restricted pregnancies. In this study, 53 cases of fetal growth restriction were compared to 53 normal fetuses delivered in consecutive sequence. Growth restricted fetuses were delivered earlier in gestation, when compared with normal growth fetuses. Maternal anemia and malnutrition have significant association with the fetal growth restriction. Maternal anthropometry, such as low BMI, had effects on placental diameter and weight, which, in turn, adversely affected fetal weight. Thus, early USG screening along with robust screening for maternal BMI, nutritional status, and anemia can assist the obstetric team in providing early diagnosis, prompt intervention, and better outcome in pregnancy with fetal growth restriction.

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Correlation of maternal body mass index with umbilical artery Doppler in pregnancies complicated by fetal growth restriction and associated outcomes

International Journal of Gynecology & Obstetrics ◽

10.1002/ijgo.13586 ◽

2021 ◽

Author(s):

Fiona Cody ◽

Sieglinde Mullers ◽

Karen Flood ◽

Julia Unterscheider ◽

Sean Daly ◽

...

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Umbilical Artery ◽

Growth Restriction ◽

Maternal Body Mass Index ◽

Maternal Body ◽

Umbilical Artery Doppler

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Antenatal detection of fetal growth restriction and stillbirth risk in mothers with high and low body mass index

Archives of Disease in Childhood - Fetal and Neonatal Edition ◽

10.1136/adc.2010.189761.7 ◽

2010 ◽

Vol 95 (Supplement 1) ◽

pp. Fa92-Fa92 ◽

Cited By ~ 2

Author(s):

M. Williams ◽

M. Southam ◽

J. Gardosi

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Growth Restriction ◽

Antenatal Detection ◽

Low Body Mass Index

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Analysis of fetal growth restriction in pregnancy in subjects attending in an obstetric clinic of a tertiary care teaching hospital

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20180876 ◽

2018 ◽

Vol 7 (3) ◽

pp. 973

Author(s):

Ashish Seal ◽

Arup Dasgupta ◽

Mousumi Sengupta ◽

Rinini Dastider ◽

Sukanta Sen

Keyword(s):

Fetal Growth ◽

Fetal Growth Restriction ◽

Intrauterine Growth Restriction ◽

Tertiary Care ◽

Growth Restriction ◽

Growth Potential ◽

Crown Rump Length ◽

Mortality And Morbidity ◽

Intrauterine Growth ◽

In Pregnancy

Background: Intrauterine growth restriction (IUGR) is defined as fetal growth less than the normal growth potential of a specific infant because of genetic or environmental factors. Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. Objective of present study was to find out incidence of IUGR and assessment and evaluation of different important changes in IUGR.Methods: Women who attended the Obstetric OPD in their 1st trimester of pregnancy and those who were thought would be able to visit the antenatal clinic for their fortnightly check-up regularly were screened for intrauterine foetal growth retardation. Women with irregular and uncertain menstrual history and where the 1st trimester USG foetal crown rump length did not corroborate with the menstrual gestational age were excluded from this study.Results: Incidence of IUGR was 18.2% and 84% were found to be asymmetrical. IUGR was found to be double among primigravids and women above 30 years. It had been observed that IUGR was associated with certain conditions like short stature (52%), pregnancy induced hypertension (24%) and anaemia (12%).Conclusions: Thus, early USG screening along with robust screening for maternal BMI, nutritional status, and anaemia can assist the obstetric team in providing early diagnosis, prompt intervention, and better outcome in pregnancy with fetal growth restriction.

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563: Antenatal detection of fetal growth restriction and stillbirth risk in mothers with high and low body mass index

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2009.10.428 ◽

2009 ◽

Vol 201 (6) ◽

pp. S209

Author(s):

Mandy Williams ◽

Andre Francis ◽

Jason Gardosi

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Growth Restriction ◽

Antenatal Detection ◽

Low Body Mass Index

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The secrets of placental mosaicism: clinical observation of the full form of confined placental trisomy 22 and literature review

10.21516/2413-1458-2020-19-1-35-40 ◽

2020 ◽

Author(s):

I.V. Komarova, A.A. Nikiforenko, A.V. Fedunyak

Keyword(s):

Prenatal Diagnosis ◽

Literature Review ◽

Fetal Growth ◽

Fetal Growth Restriction ◽

Clinical Observation ◽

Growth Restriction ◽

Favorable Outcome ◽

Full Form ◽

Placental Mosaicism ◽

In Pregnancy

Literature reports of placental mosaicism, including trisomy 22, were analyzed. The chance of correlation of placental aneuploidy with fetus aneuploidy, also the probability of complications in pregnancy and fetal growth restriction and postnatal patients growth in the cases of confined placental mosaicism, were demonstrated. The case of prenatal diagnosis of confined placental mosaicism of trisomy 22 with favorable outcome is presented. The necessity of cytogenic assay of amniocytes and fetal lymphocytes in the case of placental heteroploidy diagnosis was emphasized.

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