scholarly journals A Review on Bioactivities of Perilla: Progress in Research on the Functions of Perilla as Medicine and Food

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Miho Igarashi ◽  
Yoshifumi Miyazaki
Keyword(s):  
Evidence Based Medicine ◽  
Animal Studies ◽  
Food Product ◽  
Cytostatic Activity ◽  
Evidence Based ◽  
Physiological Effects ◽  
The Future ◽  
Based Medicine ◽  
Made In

Perilla is a useful pharmaceutical and food product and is empirically consumed by humans. However, its properties have not been evaluated extensively. In this review, we summarize the progress made in research, focusing on the bioactivities of perilla. There are manyin vitroand animal studies on the cytostatic activity and antiallergic effects, respectively, of perilla and its constituents. However, its influence on humans remains unclear. Hence, investigating and clarifying the physiological effects of perilla and its constituents on humans are imperative in the future to adhere to the ideals of evidence-based medicine.

scholarly journals Psychiatry in the future

2004 ◽  
Vol 28 (8) ◽  
pp. 277-278
Author(s):  
Frank Holloway
Keyword(s):  
Mental Health ◽  
Clinical Practice ◽  
Evidence Based Medicine ◽  
Cochrane Collaboration ◽  
Routine Clinical Practice ◽  
Evidence Based ◽  
Policy Makers ◽  
The Future ◽  
The Cochrane Collaboration ◽  
Based Medicine

In an era of evidence-based medicine, policy-makers and researchers are preoccupied by the task of ensuring that advances in research are implemented in routine clinical practice. This preoccupation has spawned a small but growing research industry of its own, with the development of resources such as the Cochrane Collaboration database and journals such as Evidence-Based Mental Health. In this paper, I adopt a philosophically quite unfashionable methodology – introspection – to address the question: how has research affected my practice?

The "Experience-Based Medicine" of the Thirteenth Century

2009 ◽  
Vol 14 (1-3) ◽  
pp. 105-130 ◽  
Author(s):  
Michael McVaugh
Keyword(s):  
Thirteenth Century ◽  
Evidence Based Medicine ◽  
Evidence Based ◽  
Physiological Effects ◽  
Based Medicine

AbstractWe should not assume that medieval physicians did not take pains to found their practice upon evidence. Academic physicians at Montpellier ca. 1300 were cautious about accepting textbook claims for the powers of drugs, and tried to verify each drug's physiological effects before using it; yet they were also flexible, ready to believe that powerful new medicines might be discovered empirically that were unknown to their authorities or superficially inconsistent with existing knowledge. Likewise, physicians were careful to observe their patients closely and to try to identify the condition from which each was suffering, and when they were unsure of the nature of an illness, they feared to administer medicines lest their known effects might be harmful to the patient. Anticipating today's "evidence-based medicine," the physician's practice involved the conscientious use of current best evidence.

scholarly journals Challenges facing early-career and mid-career researchers: potential solutions to safeguard the future of evidence-based medicine

2019 ◽  
pp. bmjebm-2019-111273 ◽  
Author(s):  
Georgia C Richards ◽  
Stephen H Bradley ◽  
Andrew B Dagens ◽  
Christoffer B Haase ◽  
Brennan C Kahan ◽  
...  
Keyword(s):  
Evidence Based Medicine ◽  
Early Career ◽  
Evidence Based ◽  
The Future ◽  
Based Medicine

scholarly journals Influência da concentração de condicionamento do ácido hidrofluorídrico na adesão protética de cerâmicas vítreas: uma revisão sistemática

2021 ◽  
Vol 10 (2) ◽  
pp. e7810212093
Author(s):  
Millena Silva Cardoso ◽  
Laís Ferrante de Faria ◽  
Camila Moreira Lima ◽  
Fabíola Pessôa Pereira Leite ◽  
Laércio Almeida de Melo
Keyword(s):  
Acid Concentration ◽  
Systematic Reviews ◽  
Evidence Based Medicine ◽  
Hydrofluoric Acid ◽  
Web Of Science ◽  
Cochrane Library ◽  
Evidence Based ◽  
Ceramic Surface ◽  
Based Medicine

Objetivo: O objetivo dessa revisão sistemática foi avaliar a influência das diferentes concentrações do ácido hidrofluorídrico (HF) no condicionamento das cerâmicas vítreas. Materiais e Métodos: Esta revisão reuniu estudos in vitro a partir de buscas nas bases Cochrane Library, Lilacs, PubMed, SciElo, Scopus e Web of Science, através dos descritores “Veneers”, “Crowns”, “Ceramics”, “Ceramic”, “Surface Treatments”, “Surface”, “Hydrofluoric Acid Concentration”, “Acid Concentration”, “Adhesion”, “Hydrofluoric Acid”. Foram incluídos estudos que investigaram os efeitos da concentração do ácido hidrofluorídrico através de diferentes concentrações entre grupos. O nível de evidência dos artigos selecionados seguiu os princípios do Oxford Center for Evidence-Based Medicine. Esta revisão seguiu as recomendações do PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyzes). Resultados: As estratégias de busca encontraram 151 títulos, dos quais 8 foram eleitos e incluídos nessa revisão. Os parâmetros de avaliação incluíram a influência da concentração do ácido quanto a resistência a flexão, rugosidade superficial, ângulo de molhamento e resistência ao microcisalhamento. Nos estudos, as cerâmicas foram condicionadas com diferentes tipos de concentração e, no geral, o HF a 5% teve o melhor desempenho. Conclusão: Os estudos encontraram mais resultados negativos para as concentrações mais baixas (1% e 3%). Apesar de algumas vantagens, o HF a 10% também não teve os melhores resultados, os quais foram de autoria do HF a 5%. Além disso, a concentração não pode ser vista como o único e principal fator importante na qualidade de adesão das cerâmicas.

scholarly journals The role of chondroprotectors in the pharmacological treatment of osteoarthritis

2019 ◽  
pp. 100-109
Author(s):  
L. K. Peshekhonova ◽  
P. A. Krasyukov
Keyword(s):  
Drug Therapy ◽  
Musculoskeletal System ◽  
Evidence Based Medicine ◽  
Cartilage Tissue ◽  
Evidence Based ◽  
Third Generation ◽  
Based Medicine ◽  
Vitro Effect

The article is devoted to third-generation slow-modifying chondroprotective drug therapy including Alflutop. The evidence-based  medicine showed and substantiated in vitro effect of the drug on the pathogenetic processes in the cartilage tissue, its promotion  of the inflammation regression in the musculoskeletal system. The authors present a series of clinical studies of top osteoarthritis doctors, which showed that Alflutop had an anti-inflammatory, chondroprotective, analgesic effect, and that the administration of  the drug allowed patients to reduce the doses of NSAIDs, and it could be used in patients with comorbid diseases. 

scholarly journals The feasibility and malleability of EBM+

2020 ◽  
Author(s):  
Jon Williamson
Keyword(s):  
Evidence Based Medicine ◽  
Association Studies ◽  
Evidence Based ◽  
Mechanistic Studies ◽  
Medical Interventions ◽  
Based Medicine ◽  
Made In ◽  
The Way

The EBM+ programme is an attempt to improve the way in which present-day evidence-based medicine (EBM) assesses causal claims: according to EBM+, mechanistic studies should be scrutinised alongside association studies. This paper addresses two worries about EBM+: (i) that it is not feasible in practice, and (ii) that it is too malleable, i.e., its results depend on subjective choices that need to be made in order to implement the procedure. Several responses to these two worries are considered and evaluated. The paper also discusses the question of whether we should have confidence in medical interventions, in the light of Stegenga's arguments for medical nihilism.

Sign in / Sign up

Export Citation Format

Share Document