scholarly journals Predictive Utility of NT-pro BNP for Infarct Size and Left Ventricle Function after Acute Myocardial Infarction in Long-Term Follow-Up

2013 ◽  
Vol 34 (3) ◽  
pp. 199-204 ◽  
Author(s):  
Paweł Kleczyński ◽  
Jacek Legutko ◽  
Tomasz Rakowski ◽  
Artur Dziewierz ◽  
Zbigniew Siudak ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Left Ventricle ◽  
Infarct Size ◽  
Left Ventricular ◽  
Left Ventricle Function ◽  
Left Ventricle Remodeling ◽  
Long Term Follow Up ◽  
Ventricle Function

PURPOSE: The aim of the study was to evaluate the utility of N-terminal pro-B-type natriuretic peptide (NT-pro BNP, pg/ml) assessment to predict infarct size and left ventricle function after ST-segment elevation myocardial infarction (STEMI) at long-term follow-up.METHODS: In 45 patients with first STEMI less than 3 hours from symptom onset treated with mechanical reperfusion NT-pro BNP was assessed early (at admission) and at 6 months. Cardiac magnetic resonance (CMR) parameters (delayed enhancement infarct size (IS, %), left ventricular end-diastolic (LVEDVI, ml/m2) and end-systolic (LVESVI, ml/m2) volume indexes) were assessed at 6 months.RESULTS: No significant correlation was found between baseline NT-pro BNP assessment and IS and left ventricle function after 6 months. There was a significant correlation between 6-month NT-pro BNP and IS (r= 0.65,p< 0.001) and left ventricle remodeling at 6 months (LVEDVI,r= 0.53,p= 0.001; LVESVI,r= 0.51,p= 0.002).CONCLUSIONS: Assessment of NT-pro BNP level 6 months after STEMI remains a good indicator of infarct size and left ventricle function at long-term follow-up.

scholarly journals Aortoventriculoplasty and left ventricle function: long-term follow-up

2004 ◽  
Vol 26 (1) ◽  
pp. 129-136 ◽  
Author(s):  
G SHARMA ◽  
M WOJTALIK ◽  
A SIWINSKA ◽  
B MROZINSKI ◽  
M PAWELECWOJTALIK ◽  
...  
Keyword(s):  
Left Ventricle ◽  
Left Ventricle Function ◽  
Long Term Follow Up ◽  
Ventricle Function

P4524His bundle pacing in patients pacemaker indication and with mildly reduced ejection fraction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
R Gardas ◽  
G Jarosinki ◽  
R Sznjader ◽  
J Biernat ◽  
K Goscinska-Bis ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Atrial Fibrillation ◽  
Left Ventricle ◽  
Ejection Fraction ◽  
Left Ventricular ◽  
Left Ventricle Function ◽  
Reduced Ejection Fraction ◽  
Permanent Pacing ◽  
Qrs Duration ◽  
Ventricle Function

Abstract Background Right ventricular pacing (RVP) can be harmful and in a number of patients leads to deterioration of left ventricle function. The deleterious effect of RVP is particularly visible in patients with reduced ejection fraction. His bundle pacing (HBP) allows ventricular stimulation without electrical and mechanical dyssynchrony and should not be associated with deterioration of left ventricle function. In some patients HBP restores electrical and mechanical synchrony. Objective The aim of the study is to evaluate effect of HBP on left ventricle function in patient with reduced left ventricle ejection fraction (LVEF. Methods Twenty-one patients with indication for permanent pacing and with (LVEF) between 35 and 50% were included into the study. Age 71,9±10,44. Men 76,2%. 13 (61,9%) patients with permanent atrial fibrillation. In 33,3% of patients there were intraventricular conduction delay (IVCD), 3 (14,3%) with LBBB, 3 (14,3%) with RBBB and 1 (4,8%) with nonspecific IVCD. 6 patients were upgraded from previously implanted pacemaker. Mean QRS duration 133,6±37,85. Baseline ejection fraction (EF) 42,6±3,21%. Clinical and echocardiographic evaluation were performed at baseline and after 6–12 months of follow up. Results QRS duration narrowed from 133,6±37,85ms to 114,3±16,90ms (p=0,033) with HBP. HBP was associated with reduction of end systolic left ventricular volume (LVES) from 91,5±31,10ml to 75,9±38,56ml (p=0,0058). EF improved from 42,6±3,21% to 48,3±7,39% (p=0,0006). Improvement in EF in patients without myocardial infarction (MI) was better (42,6±3,23% to 49,5±8,04%, p=0,0053) than in patients with MI (42,6±3,37% to 47,0±6,79%, p=0,062). Increase in EF was also better in patients with atrial fibrillation (42,7±3,19% to 49,9±8,20%, p=0,0017) than int patients with sinus rhythm (42,4±3,46% to 45,6±5,28%, p=0,17). Functional capacity assessed by NYHA class improved significantly from 2,4±0,59 to 1,7±0,58. Ejection Fraction Conclusion His bundle pacing is associated with th significant clinical and echocardiographic improvement in patients with mildly reduced left ventricular ejection fraction and indication for permanent pacing. After 6–12 moths of HBP pacing the improvement in EF is greater in patients with atrial fibrillation and without myocardial infarction.

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