Quantitative Analysis of Diffusion Weighted MR Images of Brain Tumor Using Signal Intensity Gradient Technique

The purpose of this study was to evaluate the role of diffusion weighted-magnetic resonance imaging (DW-MRI) in the examination and classification of brain tumors, namely, glioma and meningioma. Our hypothesis was that as signal intensity variations on diffusion weighted (DW) images depend on histology and cellularity of the tumor, analysing the signal intensity characteristics on DW images may allow differentiating between the tumor types. Towards this end the signal intensity variations on DW images of the entire tumor volume data of 20 subjects with glioma and 12 subjects with meningioma were investigated and quantified using signal intensity gradient (SIG) parameter. The relative increase in the SIG values (RSIG) for the subjects with glioma and meningioma was in the range of 10.08–28.36 times and 5.60–9.86 times, respectively, compared to their corresponding SIG values on the contralateral hemisphere. The RSIG values were significantly different between the subjects with glioma and meningioma (P<0.01), with no overlap between RSIG values across the two tumors. The results indicate that the quantitative changes in the RSIG values could be applied in the differential diagnosis of glioma and meningioma, and their adoption in clinical diagnosis and treatment could be helpful and informative.

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Quantitative Analysis of Diffusion Weighted MR Images of Intracerebral Haemorrhage by Signal Intensity Gradient Technique

International Journal of Medical Imaging ◽

10.11648/j.ijmi.20130101.13 ◽

2013 ◽

Vol 1 (1) ◽

pp. 12

Author(s):

Supriya S. Shanbhag

Keyword(s):

Quantitative Analysis ◽

Intracerebral Haemorrhage ◽

Signal Intensity ◽

Intensity Gradient ◽

Mr Images ◽

Diffusion Weighted ◽

Gradient Technique

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ROLE OF DIFFUSION WEIGHTED MRI IN ASSESSMENT OF BENIGN AND MALIGNANT HEPATIC FOCAL LESIONS IN ADULT AGE GROUP

QJM ◽

10.1093/qjmed/hcab106.042 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Hanan Mohammed Hanafy ◽

Ayman Mohammed Ibrahim ◽

Haytham Mohamed Nasser ◽

Moataz Metwally Elsayed

Keyword(s):

Focal Lesions ◽

Adc Value ◽

Adult Age ◽

Conventional Mri ◽

Diffusion Weighted ◽

Adc Values ◽

Weighted Magnetic Resonance Imaging ◽

Mri Sequences ◽

Value Measurement

Abstract Purpose of this study is: To evaluate the role of diffusion weighted magnetic resonance imaging in differentiation between malignant & benign hepatic focal lesions. Methods The study included 38 patients all of them were with hepatic focal lesions detected by ultrasound (between 20 and 85 years of age) referred from GIT and oncology departments. Each patient included in the study was subjected to full history taking, ultrasonography and conventional MRI sequences, post Gd- DTPA dynamic and Diffusion Weighted imaging as well as ADC value measurement. Technique was performed using a standard 1.5 Tesla unit (Ingenia, Philips). Detailed MRI and laboratory investigations were done. Results The study showed significant results were obtained between ADC values of benign and malignant hepatic focal lesions (p < 0.001). Conclusion We concluded in this study according to the obtained results that DWI sequence together with quantitative ADC values should be used as an essential sequence to supplement the conventional MRI sequences for proper detection and characterization of hepatic focal lesions.

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