scholarly journals Aseptic Splenic Abscess as Precursory Extraintestinal Manifestation of Inflammatory Bowel Disease

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Joel Brooks ◽  
Gisoo Ghaffari
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bacterial Infections ◽  
Splenic Abscess ◽  
Young Female ◽  
Review Of The Literature ◽  
Extraintestinal Manifestation ◽  
Initial Manifestation ◽  
Inflammatory Bowel ◽  
Healthy Young Female

Splenic abscesses are most often secondary to aerobic bacterial infections due toStreptococcus,Staphylococcus, andEnterococcusspecies of organisms. Sterile splenic abscesses rarely occur and diagnosis and treatment of those are challenging. We report a case of a previously healthy young female presenting with aseptic splenic abscesses as the initial manifestation of Crohn’s disease along with a review of the literature on aseptic splenic abscess as an extraintestinal manifestation of Crohn’s disease.

scholarly journals Immune Thrombocytopenic Purpura (ITP) as an Uncommon Extraintestinal Complication of Crohn’s Disease: Case Vignette and Systematic Literature Review

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Raisa Epistola ◽  
Tiffanie Do ◽  
Ritika Vankina ◽  
Daniel Wu ◽  
James Yeh ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Immune Thrombocytopenic Purpura ◽  
Case Reports ◽  
Case Vignette ◽  
Mucosal Permeability ◽  
Extraintestinal Manifestation ◽  
Thrombocytopenic Purpura ◽  
Disease Case ◽  
Inflammatory Bowel

While the association of immune thrombocytopenic purpura (ITP) and inflammatory bowel disease (IBD) has been described in a few case reports, management of ITP as an extraintestinal manifestation of Crohn’s disease (CD) is less studied. There are approximately a dozen cases describing the management of patients dually diagnosed with CD/ITP. Previous reports postulated that the mechanism of ITP in CD was through the presence of circulating immune complexes in the serum and antigenic mimicry due to increased mucosal permeability in active colitis, versus increased mucosal production of TH1-type proinflammatory cytokines during CD flares, which may account for remission of ITP with surgery for CD. We present a case of a 27-year-old man who presented with medically refractory CD and ITP who responded to surgical management with colectomy and splenectomy, along with a systematic review of the literature. These cases suggest that colectomy should be considered in the treatment of medically refractory ITP among patients with concomitant CD.

scholarly journals Granulomatous vulvitis and Gullain-Barre syndrome in pediatric Crohn’s disease: a case report

2021 ◽  
Vol 8 (6) ◽  
pp. 1121
Author(s):  
Pujitha Bandla ◽  
Bhakti Sarangi ◽  
Guruprasad H. Shankar ◽  
Varsha Sharma
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Case Report ◽  
Crohn's Disease ◽  
Bowel Disease ◽  
Gastrointestinal Symptoms ◽  
Granulomatous Inflammation ◽  
Extraintestinal Manifestation ◽  
Gastrointestinal Manifestations ◽  
Inflammatory Bowel

Granulomatous vulvitis/cheilitis may occur rarely as an extraintestinal manifestation of Crohn’s disease (CD) and may precede the development of gastrointestinal symptoms. Guillain-Barre syndrome (GBS) is associated with a wide variety of illnesses including inflammatory bowel disease. Though the immunologic abnormalities in inflammatory bowel disease may encompass both granulomatous inflammation as well as autoimmune components, the combination of CD, GBS and granulomatous vulvitis/cheilitis in the same patient has not been described in literature. We hereby reported a 14 year old girl with granulomatous vulvitis/cheilitis for 4 years preceding the development of gastrointestinal manifestations of CD, who also had GBS during the course of hospitalization.

scholarly journals Revealing the voices of women living with IBD

2021 ◽  
Author(s):  
Sarah Sebastian ◽  
Jordyn Perreault-Laird ◽  
Susan Silver
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bowel Disease ◽  
Exploratory Study ◽  
Lived Experiences ◽  
Review Of The Literature ◽  
Inflammatory Bowel ◽  
Youtube Videos

The purpose of this exploratory study is to center the voices of women who are living with inflammatory bowel disease (IBD) in order to understand their lived experiences and the kinds of support and resources they most value. Our review of the literature has indicated that studies which reveal the personal, lived, qualitative experiences with women with IBD are scarce. Instead, the existing body of research tends to be highly medicalized and expert-driven. In this study we constructed a sample of 20 YouTube videos posted by women living with Crohn's Disease and Ulcerative Colitis, who openly shared their experiences of living with the disease. Using phenomenology, coupled with an intersectional lens, we explored how living with IBD, was informed by gender, race, class and age. We hope to publish this exploratory work as a way to begin to address the gap in our understanding of the lived experiences with IBD.

scholarly journals Successful Treatment with Corticosteroids in an 11-Year-Old Patient with Crohn’s Disease and Myopericarditis—Case Report

2022 ◽  
Vol 14 (1) ◽  
pp. 26-31
Author(s):  
Joanna Ryzko ◽  
Katarzyna Zdanowicz ◽  
Dariusz Marek Lebensztejn ◽  
Urszula Daniluk
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bacterial Infections ◽  
Troponin I ◽  
Erythema Nodosum ◽  
Connective Tissue Diseases ◽  
Joint Inflammation ◽  
Skin Lesions ◽  
Inflammatory Bowel ◽  
Electrocardiogram Ecg

Extraintestinal manifestations (EIMs) are observed in 15–20% of patients with inflammatory bowel disease (IBD). One of the rare EIMs is myocarditis, the incidence of which is estimated at around 1%. The main cause of myocarditis is a viral infection. Other causes include autoimmune diseases and drug complications (sulfasalazine, mesalazine). We present the case of an 11-year-old girl with Crohn’s disease (CD) with EIMs, manifested as hip joint inflammation and erythema nodosum. At the same time, the symptoms of myopericarditis appeared with changes in electrocardiogram (ECG), echocardiography and high troponin I concentration. Therapy with corticosteroids resulted in the resolution of skin lesions and cardiological symptoms. Systemic connective tissue diseases, viral and bacterial infections were excluded in the differential diagnosis. The suspicion of mesalazine-induced EIMs was also ruled out as the symptoms resolved despite continued therapy with mesalazine. No further recurrences of myopericarditis were observed.

scholarly journals Genital and Intertriginous Rashes Refractory to Antimicrobial Treatments: Have You Thought about Crohn’s Disease?

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Candelaria O’Farrell ◽  
Annette Roberts ◽  
Claudia Riera Canales ◽  
Carrie Firestone Baum ◽  
Lina Maria Felipez
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Gastrointestinal Symptoms ◽  
Extraintestinal Manifestations ◽  
Extraintestinal Manifestation ◽  
Tract Involvement ◽  
Inflammatory Bowel ◽  
Antimicrobial Treatments ◽  
Bloody Stools

Crohn’s disease is an inflammatory bowel disease that can have multiple extraintestinal manifestations and can develop prior to, following, or simultaneously with gastrointestinal tract involvement (Aberumand et al. (2017), Georgious et al. (2006), Larsen et al. (2010), Levine and Burakoff (2011), Louis et al. (2018)). This report examines the case of a 16-year-old male with a rash of the genital, intergluteal, and inguinal regions refractory to antimicrobial treatments suspicious for an extraintestinal manifestation of Crohn’s disease. The patient was diagnosed with inflammatory, nonfistulizing colonic Crohn’s disease following presentation with gastrointestinal symptoms including abdominal pain and bloody stools 6 months after the onset of the rash. The genital lesions resolved after starting treatment for Crohn’s disease with adalimumab.

scholarly journals Keeping an Eye on Crohn’s Disease: Orbital Myositis as the Presenting Symptom

1997 ◽  
Vol 11 (6) ◽  
pp. 497-500 ◽  
Author(s):  
Carol A Durno ◽  
Robert Ehrlich ◽  
Robert Taylor ◽  
J Raymond Buncic ◽  
Peter Hughes ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Intestinal Inflammation ◽  
Extraintestinal Manifestation ◽  
Orbital Myositis ◽  
Thyroid Orbitopathy ◽  
Rare Manifestation ◽  
History Of ◽  
Appropriate Therapy ◽  
Inflammatory Bowel

Episodic periorbital swelling due to presumed orbital inflammation and myositis caused intermittent apparent proptosis and was the presenting symptom of ileocecal Crohn's disease (CD) in a teenage female with a family history of autoimmune disorders and CD. Orbital myositis, a very rare extraintestinal manifestation of inflammatory bowel disease (IBD), likely represents a process of impaired immunoregulation related to the underlying intestinal inflammation. This rare manifestation of IBD simulates the more commonly encountered thyroid orbitopathy (ophthalmopathy), but IBD should be considered if all thyroid tests are negative. It is important to recognize that orbital myositis may be an extraintestinal manifestation of Crohn's disease so that the diagnosis can be made and appropriate therapy commenced.

scholarly journals Revealing the voices of women living with IBD

2021 ◽  
Author(s):  
Sarah Sebastian ◽  
Jordyn Perreault-Laird ◽  
Susan Silver
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Bowel Disease ◽  
Exploratory Study ◽  
Lived Experiences ◽  
Review Of The Literature ◽  
Inflammatory Bowel ◽  
Youtube Videos

The purpose of this exploratory study is to center the voices of women who are living with inflammatory bowel disease (IBD) in order to understand their lived experiences and the kinds of support and resources they most value. Our review of the literature has indicated that studies which reveal the personal, lived, qualitative experiences with women with IBD are scarce. Instead, the existing body of research tends to be highly medicalized and expert-driven. In this study we constructed a sample of 20 YouTube videos posted by women living with Crohn's Disease and Ulcerative Colitis, who openly shared their experiences of living with the disease. Using phenomenology, coupled with an intersectional lens, we explored how living with IBD, was informed by gender, race, class and age. We hope to publish this exploratory work as a way to begin to address the gap in our understanding of the lived experiences with IBD.

Localization and Activity of Inflammatory Bowel Disease Using 111ln Leukocyte Imaging

1988 ◽  
Vol 27 (03) ◽  
pp. 83-86 ◽  
Author(s):  
B. Briele ◽  
F. Wolf ◽  
H. J. Biersack ◽  
F. F. Knapp ◽  
A. Hotze
Keyword(s):  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Bowel Disease ◽  
Cell Uptake ◽  
Disease Extent ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Leukocyte Imaging

A prospective study was initiated to compare the clinically proven results concerning localization/extent and activity of inflammatory bowel diseases with those of 111ln-oxine leukocyte imaging. All patients studied were completely examined with barium enema x-ray, clinical and laboratory investigations, and endoscopy with histopathology. A total of 31 leukocyte scans were performed in 15 patients (12 with Crohn’s disease, 3 with ulcerative colitis). The scans were graded by comparing the cell uptake of a lesion (when present) and a bone marrow area providing a count ratio (CR). The inflammatory lesions were correctly localized on 26 leukocyte scans, and in 21 scans the scintigraphically estimated extent of disease was identical to endoscopy. In 5 cases the disease extent was underestimated, 4 scans in patients with relapse of Crohn’s disease were falsely negative, and in one patient with remission truly negative. The scintigraphically assessed disease activity was also in a good agreement with clinical disease activity based on histopathology in all cases. We conclude that leukocyte imaging provides valuable information about localization and activity of inflammatory bowel disease.

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