scholarly journals Mucolytics for Intubated Asthmatic Children: A National Survey of United Kingdom Paediatric Intensive Care Consultants

2015 ◽  
Vol 2015 ◽  
pp. 1-5
Author(s):  
Aarjan Peter Snoek ◽  
Joe Brierley

Aim. The extent to which mucolytics are utilised in mechanically ventilated asthmatic children is unknown. We sought to establish current practice in the United Kingdom (UK) including choice of mucolytic, dose, and frequency of utilisation.Methods. A national electronic survey was distributed to UK consultants during April and May 2014. We were able to identify 168 PICU consultants at 25 institutions to whom we were able to electronically distribute a survey, representing an estimated 81% of UK NHS PICU consultants.Results. Replies were received from 87 consultants at 21 institutions (response rate=52%). Recombinant human DNase (rhDNase) does get administered by 63% of clinicians, with 54% and 19% that administer hypertonic saline or N-acetylcysteine, respectively. Of those that do administer rhDNase the majority (48%) dilute it with 0.9% saline and blindly administer it, whereas 35% administer rhDNase under bronchoscopic guidance and 17% judge the necessity for bronchoscopy according to clinical severity. 25 respondents described 7 different methods to calculate rhDNase dose. A majority (87%) of respondents expressed an interest to consider enrolling patients into an RCT that evaluates rhDNase.Conclusion. Significant variation exists regarding the necessity for mucolytics, choice of agent, optimal route, and dose in intubated asthmatic children.

2009 ◽  
Vol 30 (10) ◽  
pp. 950-954 ◽  
Author(s):  
Andrew J. Goldberg ◽  
Robert J. Sharp ◽  
Paul Cooke

Gut ◽  
1997 ◽  
Vol 40 (2) ◽  
pp. 192-195 ◽  
Author(s):  
J G Silcock ◽  
M G Bramble

2020 ◽  
pp. 238008442097865
Author(s):  
O. Bailey ◽  
C.R. Vernazza ◽  
S. Stone ◽  
L. Ternent ◽  
A.-G. Roche ◽  
...  

Introduction: A European Union amalgam phase-down has recently been implemented. Publicly funded health care predominates in the United Kingdom with the system favoring amalgam use. The current use of amalgam and its alternatives has not been fully investigated in the United Kingdom. Objectives: The study aimed to identify direct posterior restorative techniques, material use, and reported postoperative complication incidence experienced by primary care clinicians and differences between clinician groups. Methods: A cross-sectional survey was distributed to primary care clinicians through British dentist and therapist associations (11,092 invitations). The questionnaire sought information on current provision of direct posterior restorations and perceived issues with the different materials. Descriptive statistical and hypothesis testing was performed. Results: Dentists’ response rate was 14% and therapists’ estimated minimum response rate was 6% (total N = 1,513). The most commonly used restorative material was amalgam in molar teeth and composite in premolars. When placing a direct posterior mesio-occluso-distal restoration, clinicians booked on average 45% more time and charged 45% more when placing composite compared to amalgam ( P < 0.0001). The reported incidences of food packing and sensitivity following the placement of direct restorations were much higher with composite than amalgam ( P < 0.0001). Widely recommended techniques, such as sectional metal matrix use for posterior composites, were associated with reduced food packing ( P < 0.0001) but increased time booked ( P = 0.002). Conclusion: Amalgam use is currently high in the publicly funded sector of UK primary care. Composite is the most used alternative, but it takes longer to place and is more costly. Composite also has a higher reported incidence of postoperative complications than amalgam, but time-consuming techniques, such as sectional matrix use, can mitigate against food packing, but their use is low. Therefore, major changes in health service structure and funding and posterior composite education are required in the United Kingdom and other countries where amalgam use is prevalent, as the amalgam phase-down continues. Knowledge Transfer Statement: This study presents data on the current provision of amalgam for posterior tooth restoration and its directly placed alternatives by primary care clinicians in the United Kingdom, where publicly funded health care with copayment provision predominates. The information is important to manage and plan the UK phase-down and proposed phase-out of amalgam and will be of interest to other, primarily developing countries where amalgam provision predominates in understanding some of the challenges faced.


2018 ◽  
Vol 15 (4) ◽  
pp. 476-479 ◽  
Author(s):  
Nicholas Bullock ◽  
Martin Steggall ◽  
Gareth Brown

2020 ◽  
Vol 46 (1) ◽  
pp. 284-294
Author(s):  
◽  
Matthew Ellis ◽  
George Garas ◽  
John Hardman ◽  
Maha Khan ◽  
...  

1995 ◽  
Vol 23 (3) ◽  
pp. 208-217 ◽  
Author(s):  
Leslie J. Francis ◽  
Mandy Robbins

A detailed questionnaire was mailed to all institutions involved in the initial training of Christian ministers of religion within the United Kingdom. The 95 completed replies represent an 85% response rate. The data suggest that, although few full-time ministry educators possess a recognized qualification in psychology, the climate is generally favorable to psychology within programs of initial ministry training. The data also distinguish between four different levels on which psychology may contribute to such programs: areas given high priority in initial ministry training and in which psychology is already perceived as making an important contribution; areas given middle ranking priority and in which psychology is perceived as making an important contribution; areas to which psychology is seen as making a very positive contribution but which are perceived as being of little importance in initial ministry training; and areas given high priority but in which psychology is perceived as having little to offer. Suggestions are offered for the promotion of psychology on these different levels.


Rheumatology ◽  
2017 ◽  
Vol 56 (suppl_2) ◽  
Author(s):  
Daniel P. Hawley ◽  
Helen E. Foster ◽  
Michael W. Beresford ◽  
Athimalaipet Ramanan ◽  
Tim Rapley ◽  
...  

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