scholarly journals Middle Cerebral Artery Atherosclerotic Plaques in Recent Small Subcortical Infarction: A Three-Dimensional High-resolution MR Study

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
Xiao-Dong Zou ◽  
Yiu-Cho Chung ◽  
Lei Zhang ◽  
Ying Han ◽  
Qi Yang ◽  
...  
Keyword(s):  
High Resolution ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Vessel Wall ◽  
Three Dimensional ◽  
Contralateral Side ◽  
Vessel Wall Imaging ◽  
Atherosclerotic Plaques ◽  
Contrast Enhanced ◽  
Wall Imaging

Purpose. Conventional two-dimensional vessel wall imaging has been used to depict the middle cerebral artery (MCA) wall in patients with recent small subcortical infarctions (RSSIs). However, its clinical use has been limited by restricted spatial coverage, low signal-to-noise ratio (SNR), and long scan time. We used a novel three-dimensional high-resolution MR imaging (3D HR-MRI) technique to investigate the presence, locations, and contrast-enhanced patterns of MCA plaques and their relationship with RSSI.Methods. Nineteen consecutive patients with RSSI but no luminal stenosis on MR angiography were prospectively enrolled. 3D HR-MRI was performed using a T1w-SPACE sequence at 3.0 T. The presence, locations, and contrast-enhanced patterns of the MCA plaques on the ipsilateral and contralateral sides to the RSSI were analyzed.Results. Eighteen patients successfully completed the study. MCA atherosclerotic plaques occurred more frequently on the ipsilateral than the contralateral side to the RSSI (72.2% versus 33.3%,P=0.044). The occurrence of superiorly located plaques was significantly higher on the ipsilateral than the contralateral side of the MCA (66.7% versus 27.8%;P=0.044).Conclusions. Superiorly located plaques are closely associated with RSSI. 3D high-resolution vessel wall imaging may be a potential tool for etiologic assessment of ischemic stroke.

Utility of minimum intensity projection images based on three-dimensional CUBE T1 weighted imaging for evaluating middle cerebral artery stenosis

2021 ◽  
Vol 94 (1121) ◽  
pp. 20210145
Author(s):  
Yejun Wu ◽  
Fangbing Li ◽  
Yilin Wang ◽  
Tianxiang Hu ◽  
Liang Xiao
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Vessel Wall ◽  
Spin Echo ◽  
Three Dimensional ◽  
High Sensitivity ◽  
Vessel Wall Imaging ◽  
Acquisition Time ◽  
Dimensional Variable ◽  
Wall Imaging

Objective: This study investigated the diagnostic performance of MinIP images based on three-dimensional variable-flip-angle turbo spin echo T1 weighted imaging (3D CUBE T1WI) from high-resolution vessel wall magnetic resonance imaging for detecting middle cerebral artery (MCA) stenosis. Methods: A total of 63 consecutive patients were included in this study. MinIP images were reconstructed using 3D CUBE T1WI as the source images. The degree and length of MCA stenosis were measured on MinIP images and were compared with digital subtraction angiography (DSA) as the reference standard. Results: The intra- and interobserver agreement for both the rate and length of MCA stenosis were excellent for the MinIP images. There was also excellent agreement in the degree of MCA stenosis calculated using MinIP images and DSA. MinIP images had a high sensitivity, specificity for diagnosing MCA stenosis. There was a good correlation between the two methods for measuring the rate and length of MCA stenosis. Conclusion: MinIP images based on 3D CUBE T1WI are highly consistent with DSA for evaluating the degree and length of MCA stenosis. Advances in knowledge: MinIP images can be produced as a derivative from vessel wall imaging and implemented as an adjunct to vessel wall imaging without extra acquisition time.

scholarly journals Spontaneous Middle Cerebral Artery (MCA) dissection and stenosis: Role of vessel wall imaging and 3D-RA endoluminal view as adjunct diagnostic tools in endovascular therapy

2021 ◽  
Vol 25 ◽  
pp. 101170
Author(s):  
Mohd Fandi Al Khafiz Kamis ◽  
Mohd Naim Mohd Yaakob ◽  
Ezamin Abdul Rahim ◽  
Ahmad Sobri Muda ◽  
Mohamad Syafeeq Faeez Md Noh
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Endovascular Therapy ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Diagnostic Tools ◽  
Wall Imaging

scholarly journals Practical Value of Three-dimensional High Resolution Magnetic Resonance Vessel Wall Imaging in Identifying Suspicious Intracranial Vertebrobasilar Dissecting Aneurysms

2019 ◽  
Author(s):  
Xianjin Zhu ◽  
Hancheng Qiu ◽  
Ferdinand K Hui ◽  
Yiqun Zhang ◽  
Yun-e Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Vessel Wall ◽  
Three Dimensional ◽  
Vessel Wall Imaging ◽  
Catheter Angiography ◽  
Double Lumen ◽  
Post Contrast ◽  
Dissecting Aneurysms ◽  
Wall Imaging

Abstract Background: Direct evidence of intimal flaps, double lumen and intramural haematomas (IMH) is difficult to detect on conventional angiography in most intracranial vertebrobasilar dissecting aneurysms (VBDAs). Our purpose was to assess the value of three-dimensional high-resolution magnetic resonance vessel wall imaging (3D HRMR VWI) for identifying VBDAs. Methods: Between August 2013 and January 2016, consecutive patients with suspicious VBDAs were prospectively enrolled to undergo catheter angiography and VWI (pre- and post-contrast). The lesion was diagnosed as definite VBDA when presenting direct signs of dissection; as possible when only presenting indirect signs; and as segmental ectasia when there was local dilation and wall thickness similar to adjacent normal artery’s without mural thrombosis. Results: Twenty-one patients with 27 lesions suspicious for VBDAs were finally included. Based on findings of VWI and catheter angiography, definite VBDA was diagnosed in 25 and 7 lesions (92.6%, vs 25.9%, p = 0.000), respectively; possible VBDA in 0 and 20 (0 vs 74.1%), respectively; and segmental ectasia in 2 and 0 (7.4% vs 0%), respectively. On VWI and catheter angiography, intimal flap was detected in 21 and 7 lesions (77.8% vs 25.9%, p=0.001), respectively; double lumen sign in 18 and 7 (66.7% vs 25.9%, p=0.003), respectively; and IMH sign in 14 and 0 (51.9% vs 0), respectively. Conclusions: 3D HRMR VWI was superior to catheter angiography in achieving definite diagnosis of intracranial VBDAs with higher rate of detection of direct dissection signs; and allowed a promising way to differentiate between VBDA and segmental ectasia.

Abstract WP162: Automatic Detection of Middle Cerebral Artery Plaque on T2-weighted Vessel Wall Imaging

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Yannan Yu ◽  
Irma Ravkic ◽  
Wei-Hai Xu ◽  
Ming-Li Li ◽  
David Liebeskind ◽  
...  
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Vessel Wall ◽  
Automatic Detection ◽  
Vessel Wall Imaging ◽  
Wall Imaging

scholarly journals Practical Value of Three-dimensional High Resolution Magnetic Resonance Vessel Wall Imaging in Identifying Suspicious Intracranial Vertebrobasilar Dissecting Aneurysms

2020 ◽  
Author(s):  
Xianjin Zhu ◽  
Hancheng Qiu ◽  
Ferdinand K Hui ◽  
Yiqun Zhang ◽  
Yun-e Liu ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
High Resolution ◽  
Vessel Wall ◽  
Three Dimensional ◽  
Vessel Wall Imaging ◽  
Definite Diagnosis ◽  
Catheter Angiography ◽  
Double Lumen ◽  
Dissecting Aneurysms ◽  
Wall Imaging

Abstract Background: Direct evidence of intimal flaps, double lumen and intramural haematomas (IMH) is difficult to detect on conventional angiography in most intracranial vertebrobasilar dissecting aneurysms (VBDAs). Our purpose was to assess the value of three-dimensional high-resolution magnetic resonance vessel wall imaging (3D HRMR VWI) for identifying VBDAs. Methods: Between August 2013 and January 2016, consecutive patients with suspicious VBDAs were prospectively enrolled to undergo catheter angiography and VWI (pre- and post-contrast). The lesion was diagnosed as definite VBDA when presenting direct signs of dissection; as possible when only presenting indirect signs; and as segmental ectasia when there was local dilation and wall thickness similar to adjacent normal artery’s without mural thrombosis. Results: Twenty-one patients with 27 lesions suspicious for VBDAs were finally included. Based on findings of VWI and catheter angiography, definite VBDA was diagnosed in 25 and 7 lesions (92.6%, vs 25.9%, p = 0.000), respectively; possible VBDA in 0 and 20 (0 vs 74.1%), respectively; and segmental ectasia in 2 and 0 (7.4% vs 0%), respectively. On VWI and catheter angiography, intimal flap was detected in 21 and 7 lesions (77.8% vs 25.9%, p=0.001), respectively; double lumen sign in 18 and 7 (66.7% vs 25.9%, p=0.003), respectively; and IMH sign in 14 and 0 (51.9% vs 0), respectively. Conclusions: 3D HRMR VWI could detect direct dissection signs more frequently than catheter angiography. This may help obtain definite diagnosis of intracranial VBDAs, and allow accurate differentiation between dissecting aneurysm and segmental ectasia as well. Further prospective study with larger sample was required to investigate the superiority of HRMR VWI for definite diagnosis of intracranial VBDAs than catheter angiography

Middle cerebral artery geometric features are associated with plaque distribution and stroke

Neurology ◽  
2018 ◽  
Vol 91 (19) ◽  
pp. e1760-e1769 ◽  
Author(s):  
Yan Nan Yu ◽  
Ming-Li Li ◽  
Yu-Yuan Xu ◽  
Yao Meng ◽  
Harry Trieu ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Confidence Interval ◽  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Odds Ratio ◽  
Vessel Wall ◽  
Vessel Wall Imaging ◽  
Geometric Features ◽  
Insight Into ◽  
Wall Imaging

ObjectiveWe aimed to investigate the geometric features of the middle cerebral artery (MCA) and their relevance to plaque distribution and ischemic stroke.MethodsWe reviewed our institutional vessel wall imaging database. Patients with symptomatic MCA atherosclerosis, asymptomatic MCA atherosclerosis, or without MCA atherosclerosis were included. The MCA geometric features, including M1 segment shape and M1 curve orientation, were defined on magnetic resonance angiography. Plaque distribution and other plaque parameters were identified on vessel wall imaging. The association among MCA geometric features, plaque distribution, and ischemic stroke were analyzed.ResultsA total of 977 MCAs were analyzed (87 atherosclerotic symptomatic MCAs, 459 atherosclerotic asymptomatic MCAs, and 431 plaque-free MCAs). Overall, curved M1 segments were the predominant shape across all groups. In 91.1% of curved atherosclerotic MCAs, the plaque involved the inner wall of the curve. Plaque not involving the inner wall was shorter (p < 0.0001) and thinner (p = 0.005) compared to plaque involving the inner wall. Inferior plaque was observed in 39.9% of inferior-oriented M1 curves compared to 21.7% in non–inferior-oriented M1 curves (p < 0.0001). The absence of an inferior-oriented M1 curve (odds ratio 0.45, 95% confidence interval 0.27–0.77) and presence of superior plaque (odds ratio 2.67, 95% confidence interval 1.52–4.67) were independently associated with stroke after adjusting for plaque length and thickness, degree of stenosis, and remodeling ratio.ConclusionsMCA geometric features are associated with plaque distribution and stroke. Our findings provide insight into the vascular pathophysiology of MCA atherosclerosis.

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