scholarly journals Pure Oats as Part of the Canadian Gluten-Free Diet in Celiac Disease: The Need to Revisit the Issue

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
M. Cristina P. de Souza ◽  
Marie-Eve Deschênes ◽  
Suzanne Laurencelle ◽  
Patrick Godet ◽  
Claude C. Roy ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Current Knowledge ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Adults And Children ◽  
Oat Cultivars ◽  
Actual Contribution ◽  
The Impact ◽  
Long Term Studies

The question about recommending pure, noncontaminated oats as part of the gluten-free diet of patients with celiac disease remains controversial. This might be due to gluten cross contamination and to the possible immunogenicity of some oat cultivars. In view of this controversy, a review of the scientific literature was conducted to highlight the latest findings published between 2008 and 2014 to examine the current knowledge on oats safety and celiac disease in Europe and North America. Results showed that regular oats consumed in Canada are largely contaminated. Overall, the consumption of pure oats has been generally considered to be safe for adults and children. However, it appears that some oat cultivars may trigger an immune response in sensitive individuals. Therefore, further long-term studies on the impact of consumption of oats identifying the cultivar(s) constitute an important step forward for drawing final recommendations. Furthermore, a closer and more accurate monitoring of the dietary intake of noncontaminated oats would be paramount to better determine what its actual contribution in the gluten-free diet of adults and children with celiac disease are in order to draw sound recommendations on the safety of pure oats as part of the gluten-free diet.

scholarly journals Rationale for Timing of Follow-Up Visits to Assess Gluten-Free Diet in Celiac Disease Patients Based on Data Mining

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 357
Author(s):  
Alfonso Rodríguez-Herrera ◽  
Joaquín Reyes-Andrade ◽  
Cristina Rubio-Escudero
Keyword(s):  
Data Mining ◽  
Celiac Disease ◽  
Cultural Context ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Adherence To Diet ◽  
And Gender ◽  
Few Data

The assessment of compliance of gluten-free diet (GFD) is a keystone in the supervision of celiac disease (CD) patients. Few data are available documenting evidence-based follow-up frequency for CD patients. In this work we aim at creating a criterion for timing of clinical follow-up for CD patients using data mining. We have applied data mining to a dataset with 188 CD patients on GFD (75% of them are children below 14 years old), evaluating the presence of gluten immunogenic peptides (GIP) in stools as an adherence to diet marker. The variables considered are gender, age, years following GFD and adherence to the GFD by fecal GIP. The results identify patients on GFD for more than two years (41.5% of the patients) as more prone to poor compliance and so needing more frequent follow-up than patients with less than 2 years on GFD. This is against the usual clinical practice of following less patients on long term GFD, as they are supposed to perform better. Our results support different timing follow-up frequency taking into consideration the number of years on GFD, age and gender. Patients on long term GFD should have a more frequent monitoring as they show a higher level of gluten exposure. A gender perspective should also be considered as non-compliance is partially linked to gender in our results: Males tend to get more gluten exposure, at least in the cultural context where our study was carried out. Children tend to perform better than teenagers or adults.

A Single Institution’s Experience of Primary Headache in Children With Celiac Disease

2019 ◽  
Vol 35 (1) ◽  
pp. 37-41 ◽  
Author(s):  
Grant L. Hom ◽  
Brian L. Hom ◽  
Barbara Kaplan ◽  
A. David Rothner
Keyword(s):  
Celiac Disease ◽  
Tissue Transglutaminase ◽  
Primary Headache ◽  
Tension Type Headache ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Phone Survey ◽  
Type Headache ◽  
The Impact ◽  
Histologic Changes

Background: Few studies exist examining the frequency of primary headache in children with celiac disease and the impact of a gluten-free diet on primary headache symptomology. This study explores characteristics and frequency of headaches in children with celiac disease and response to gluten-free diet at a single institution. Methods: Medical records were reviewed for children with celiac disease confirmed by the presence of elevated tissue transglutaminase IgA levels and histologic changes consistent with the diagnosis of celiac disease on small bowel biopsy. Eligible participants were contacted via letter for participation in a phone survey regarding headaches. Phone interviews were conducted 2 weeks after notification and lasted approximately 10 minutes. Headaches were classified according to ICHD-3 criteria. Results: 247 eligible patients or their families were contacted. A total of 132 (53.44%) agreed to participate. One participant was excluded due to insufficient information provided. Overall, 51 of 131 participants had recurrent headache defined as at least 1 episode per month (39%, 95% confidence interval [CI]: 31%-47%) and 33 had migraine with or without aura (25%, 95% CI: 18%-33%). Twenty-eight had frequent tension-type headache (22%, 95% CI: 15%-29%). Thirty-two participants noted headaches before a confirmed diagnosis of celiac disease. Twenty-two of 32 participants (68.75%) noticed decreased headache frequency or intensity, or both, after starting the gluten-free diet. Conclusion: This study suggests that at least one-third of children and adolescents with celiac disease have recurrent headaches at the time of diagnosis. A gluten-free diet led to improved headache symptomology in a significant number of these patients.

A Phase I Study to Determine Safety, Tolerability and Bioactivity of Nexvax2® in HLA DQ2+ Volunteers With Celiac Disease Following a Long-Term, Strict Gluten-Free Diet

2011 ◽  
Vol 140 (5) ◽  
pp. S-437-S-438 ◽  
Author(s):  
Gregor J. Brown ◽  
James Daveson ◽  
Joanne K. Marjason ◽  
Rose A. Ffrench ◽  
Danielle Smith ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Phase I ◽  
Phase I Study ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Hla Dq2

S2041 Improved Performance of Celiac Disease-Related Serology Tests in Predicting the Degree of Patients' Compliance With Long-Term Gluten-Free Diet. New Cut-Offs are Necessary

2010 ◽  
Vol 138 (5) ◽  
pp. S-307
Author(s):  
Fabio D. Nachman ◽  
Emilia Sugai ◽  
Horacio Vázquez ◽  
Andrea F. Gonzalez ◽  
Paola J. Andrenacci ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Improved Performance

Persistent Duodenal Intraepithelial Lymphocytosis Despite a Long-Term Strict Gluten-Free Diet in Celiac Disease

2012 ◽  
Vol 107 (10) ◽  
pp. 1563-1569 ◽  
Author(s):  
Ilus Tuire ◽  
Lähdeaho Marja-Leena ◽  
Salmi Teea ◽  
Haimila Katri ◽  
Partanen Jukka ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Intraepithelial Lymphocytosis

Urinary nitric oxide metabolites in children with celiac disease after long-term consumption of oats-containing gluten-free diet

2014 ◽  
Vol 49 (11) ◽  
pp. 1311-1317 ◽  
Author(s):  
Dimitrios Tapsas ◽  
Karin Fälth-Magnusson ◽  
Lotta Högberg ◽  
Tony Forslund ◽  
Tommy Sundqvist ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Celiac Disease ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Nitric Oxide Metabolites

scholarly journals Design of a dietary intervention to assess the impact of a gluten-free diet in a population with type 1 Diabetes and Celiac Disease

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Esther Assor ◽  
Margaret A. Marcon ◽  
Natasha Hamilton ◽  
Marilyn Fry ◽  
Tammy Cooper ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Celiac Disease ◽  
Dietary Intervention ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
The Impact

The impact of a gluten-free diet on the growth pattern of Saudi children with celiac disease

2021 ◽  
pp. 1-17
Author(s):  
Omar Ibrahim Saadah
Keyword(s):  
Celiac Disease ◽  
Growth Pattern ◽  
Laboratory Data ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Z Score ◽  
The Mean ◽  
The Impact ◽  
Igfbp 3

Objective: To describe the growth pattern of children with celiac disease (CD) after introduction of a gluten-free diet (GFD). Methods: In this retrospective, children 2–16 years old with biopsy-proven CD in 2015–2018 were included in the study conducted at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. Serial measurements of height-for-age z-score (HAZ) and weight-for-age z-score (WAZ), were recorded at 0, 4, 8, 12, and 16 months. Data on insulin-like growth hormone-1 (IGF-1) and insulin-like growth factor binding protein-3 (IGFBP-3) obtained at diagnosis and during follow-up were retrieved. Clinical, demographic, and laboratory data were extracted from patients' medical files. Results: The median age for the patients was 8.9 years (range, 2.4–16 years). Males constituted 53.2%. The mean WAZ at diagnosis was -2.8±1.9 and the mean HAZ was -3±0.99. Trend analysis indicated a significant time effect for WAZ (p<0.001) and for HAZ (p<0.001). The mean IGF-1 was 133.4±96.8 ng/ml and the mean IGFBP-3 was 3174±1081 ng/ml. There was significant increase in the secretion of IGF-1 (p=0.01) and IGFBP-3 (p=0.004) during the first 8 months of a GFD. Conclusion: The administration of a GFD for Saudi children with CD normalizes their growth parameters within 16 months of follow-up and improves the endogenous secretion of growth factors. Keywords: Celiac disease, growth, child, Continuous...

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