scholarly journals Prevalence and Correlates of Peripheral Arterial Disease in Nigerians with Type 2 Diabetes

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
D. O. Soyoye ◽  
R. T. Ikem ◽  
B. A. Kolawole ◽  
K. S. Oluwadiya ◽  
R. A. Bolarinwa ◽  
...  

Background. Peripheral arterial disease (PAD) is a major risk factor for nonhealing foot ulcers in people with diabetes. A number of traditional risk factors have been reported to be associated with PAD; however, there may be a need to consider nontraditional risk factors especially in some vulnerable populations. This study determined the prevalence and risk factors associated with PAD in diabetics.Methods. One hundred and fifty type 2 diabetics and an equal number of age- and sex-matched apparently healthy controls were studied. Assessment of PAD was made using history, palpation of lower limb vessels, and measurement of ankle-brachial index (ABI). Statistically significant differences between categorical and continuous variables were determined using Chi square (χ2) and Studentt-tests, respectively. Regression analysis was done to determine the associated risk factors for PAD.Results. Prevalence of PAD using ABI was 22.0% and 8.0% among diabetic and nondiabetic populations, respectively. Peripheral arterial disease was associated with age, male gender, waist circumference, and high-sensitivity C-reactive protein.Conclusion. This study highlights the high prevalence of PAD in people with type 2 diabetes mellitus and in apparently healthy controls; age, male gender, abdominal obesity, and high hs-CRP values were the associated risk factors.

2020 ◽  
Vol 17 (6) ◽  
pp. 147916412096699
Author(s):  
Preaw Suwannasrisuk ◽  
Sarinya Sattanon ◽  
Watcharaporn Taburee ◽  
Pantitra Singkheaw ◽  
Non Sowanna ◽  
...  

In diabetes patients, urban lifestyle has been concerned as one of the risk factors for peripheral arterial disease (PAD). The aims of this study were to find out the prevalence and associated risk factors of PAD in type 2 diabetes patients who live in a non-urban community area. A total of 885 participants with type 2 diabetes mellitus were enrolled from six primary care units in the health network centered at Naresuan University Hospital, Phitsanulok, between May and June 2018. Ankle-brachial index (ABI) was performed in all subjects using a vascular screening device. PAD was defined by an ABI value of 0.9 or lesser at least on one leg. The predictors of PAD were analyzed using multiple logistic regression. The prevalence of PAD was 7.2% among 884 evaluable patients. Diabetic neuropathy and a history of macrovascular complications were significant predictors of PAD.


2007 ◽  
Vol 78 (2) ◽  
pp. 246-253 ◽  
Author(s):  
Cristina Bianchi ◽  
Giuseppe Penno ◽  
Francesca Pancani ◽  
Alessia Civitelli ◽  
Alberto Piaggesi ◽  
...  

2021 ◽  
Vol 27 (6) ◽  
pp. S51
Author(s):  
Martha Rosana ◽  
Ninik Saragih ◽  
Pradana Soewondo ◽  
Dicky L. Tahapary ◽  
Lusiani Rusdi ◽  
...  

2020 ◽  
Vol 17 (2) ◽  
pp. 147916412091484
Author(s):  
Clemens Höbaus ◽  
Carsten Thilo Herz ◽  
Thomas Wrba ◽  
Renate Koppensteiner ◽  
Gerit-Holger Schernthaner

Objective: To investigate a possible beneficial effect of strict glycaemic control on all-cause mortality in patients with peripheral arterial disease and type 2 diabetes mellitus. Methods: A total of 367 mainly older peripheral arterial disease patients [age: 69 (62–78) years, 34% women, Fontaine stage I–II] were categorized according to glycaemic control, that is, (a) no type 2 diabetes mellitus, (b) strict glucose control (HbA1c < 53 mmol/mol) and (c) lenient glucose control (HbA1c ⩾ 53 mmol/mol) at inclusion and by mean HbA1c over the first study year. Mortality was analysed using Kaplan–Meier and Cox-regression analyses after 7 years. Results: The combination of type 2 diabetes mellitus and peripheral arterial disease reduced survival from 78.8% to 68.9% in comparison to patients without type 2 diabetes mellitus ( p = 0.023). Patients with strict glucose control (75%) were associated with increased survival in comparison to patients with lenient glucose control (58.9%) stratified by mean HbA1c ( p = 0.042). Baseline cardiovascular risk factors were similar in those type 2 diabetes mellitus patients. In this peripheral arterial disease cohort HbA1c (hazard ratio: 1.3, 1.04–1.63), age (hazard ratio: 1.7, 1.3–2.3) and C-reactive protein (hazard ratio: 1.5, 1.2–2.0) remained independent associates for mortality adjusted for cardiovascular risk factors and diabetes duration. Conclusion: Older patients with peripheral arterial disease and type 2 diabetes mellitus still benefit from strict glucose control in a cohort of patients with similar distribution of cardiovascular risk factors.


Sign in / Sign up

Export Citation Format

Share Document