scholarly journals Assessment of Anterior Segment Measurements with Swept Source Optical Coherence Tomography before and after Ab Interno Trabeculotomy (Trabectome) Surgery

2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Handan Akil ◽  
Ping Huang ◽  
Vikas Chopra ◽  
Brian Francis
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Open Angle Glaucoma ◽  
Anterior Segment ◽  
Open Angle ◽  
Swept Source ◽  
Significant Difference ◽  
Trabectome Surgery ◽  
Before And After

Purpose. To compare the changes of anterior segment parameters, assessed by swept source anterior segment optical coherence tomography (AS-OCT) after combined Trabectome-cataract surgery and Trabectome-only surgery in open angle glaucoma patients.Methods. Thirty-eight eyes of 24 patients with open angle glaucoma were scanned with swept source AS-OCT before and 4 weeks after combined Trabectome-cataract or Trabectome-only surgery. Intraocular pressure, number of medications, and AS-OCT parameters, such as angle opening distance at 500 and 750 μm from the scleral spur (AOD500 and AOD750), trabecular-iris space area at 500 and 750 mm2(TISA500, TISA750), angle recess area at 500 and 750 mm2(ARA500, ARA750), trabecular iris angle (TIA), anterior chamber depth (ACD), anterior chamber width (ACW), and anterior chamber volume (ACV), were obtained before the surgery. These parameters were compared to evaluate whether the outcome of the surgery differed among the patients after the surgery. The width of the trabecular cleft was also measured for both groups.Results. The reduction of IOP and number of medications was found to be statistically significant in both groups (p<0.001). ACD, ACV, and angle parameters such as AOD 500/750, TISA 500/750, ARA 500/750, and TIA500 showed significantly greater changes from the preoperative values to postoperative 1st month values in combined Trabectome-cataract surgery group (p<0.05), whereas Trabectome-only group did not show statistically significant difference (p>0.05). There was no statistically significant difference between two groups for the width of the trabecular cleft (p=0.7).Conclusion. Anterior chamber angle parameters measured with swept source AS-OCT may be useful for evaluating glaucoma patients before and after Trabectome surgery with or without cataract surgery.

scholarly journals Assessment of anterior chamber configuration changes after phacoemulsification with swept-source optical coherence tomography

2019 ◽  
Author(s):  
Man Hu ◽  
Qian Zheng ◽  
Zhangliang Li ◽  
Pingjun Chang ◽  
Yun-e Zhao
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Optical Coherence ◽  
Swept Source ◽  
Narrow Angle ◽  
Age Related ◽  
Shallow Anterior Chamber

Abstract Background To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT). Methods This was a prospective case control study; 60 eyes of 60 patients who underwent cataract surgery. Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were classified into two groups, shallow anterior chamber group (30 eyes) and normal anterior chamber group (30 eyes). AS-SS-OCT was used to measure ACD and angle parameters angle opening distance (AOD), angle recess area (ARA), trabecular iris space area(TISA), and trabecular iris angle (TIA). Serial changes in each group were measured before and 3 months after phacoemulsification and IOL, and the differences between the two groups were compared. Results All angle parameters including ACD, AOD, ARA, TISA, and TIA in both groups at 3 months after cataract surgery were significantly different from the preoperative values (p<0.01). In addition, we found significant differences of all angle parameters between groups of shallow anterior chamber (SAC) and normal anterior chamber (NAC) (All P< 0.05). Besides, the TISA750 in superior quadrant and anterior chamber volume (ACV) were significantly smaller in the group of SAC than those in the group of NAC (P = 0.041 and 0.002, respectively). Conclusions The parameters of anterior chamber increased significantly in both two groups but not increase to the same extent 3 months after phacoemulsification. Iris thickening may also be one of the narrow angle factors,not just age-related lens thickening.

scholarly journals Effect of prostaglandin analogues on anterior scleral thickness and corneal thickness in patients with primary open-angle glaucoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ji-Hye Park ◽  
Chungkwon Yoo ◽  
Hyun Woo Chung ◽  
Yong Yeon Kim
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Corneal Thickness ◽  
Anterior Segment ◽  
Open Angle ◽  
Prostaglandin Analogues ◽  
First Line Therapy ◽  
Significant Difference ◽  
Before And After ◽  
Treatment Naïve

AbstractProstaglandin (PG) analogues are usually prescribed as a first-line therapy in patients with glaucoma because of its once-daily dosing benefit and effective intraocular pressure (IOP) reduction. However, the mechanism of PG analogues is not completely understood. In this study, we investigated the effect of PG analogues on the anterior scleral thickness (AST) in treatment-naïve eyes with primary open-angle glaucoma using anterior segment optical coherence tomography. The AST was measured at the location of the scleral spur, 1000 μm, and 2000 μm posterior to the scleral spur and was compared before and after using the medications for 3 months and 1 year. Among 54 patients enrolled in this study, 31 patients used prostaglandin analogues and 23 patients used dorzolamide/timolol fixed combination (DTFC) drugs. There was no significant difference in untreated IOP, glaucoma severity, and baseline AST values between the two groups. While there was no significant changes in AST after using the DTFC drugs, the AST at all 3 locations showed a significant reduction in both the nasal and temporal sectors after using PG analogues for 1 year (all, P < 0.05). These findings suggest that the AST reduction after using PG analogues might be related with the increased uveoscleral outflow.

scholarly journals Assessment of anterior chamber configuration changes after phacoemulsification with swept-source optical coherence tomography

2020 ◽  
Author(s):  
Man Hu ◽  
Qian Zheng ◽  
Zhangliang Li ◽  
Pingjun Chang ◽  
Yun-e Zhao
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Chamber ◽  
Optical Coherence ◽  
Anterior Chamber Angle ◽  
Swept Source ◽  
Narrow Angle ◽  
Significant Difference ◽  
Shallow Anterior Chamber ◽  
Chamber Angle

Abstract Background: To assess the changes of anterior chamber angle in patients with shallow anterior chamber and normal anterior chamber after phacoemulsification and intraocular lens implantation (IOL) using anterior segment swept-source optical coherence tomography (AS-SS-OCT). Methods: This was a prospective case control study; 60 eyes of 60 patients who scheduled for cataract surgery with normal intraocular pressure (IOP). Based on anterior chamber depth (ACD) and gonioscopy findings, the eyes were classified into two groups: shallow anterior chamber group with narrow angle (SAC group, 30 eyes)；and normal anterior chamber group with wide angle (NAC group, 30 eyes). Measurements of ACD, anterior chamber volume (ACV), Iris volume (IV), lens vault (LV) , angle opening distance (AOD), angle recess area (ARA), trabecular iris space area (TISA), and trabecular iris angle (TIA) were conducted in each group before and 3 months after surgery. Differences between the two groups were compared. Results: There was no significant difference in age, axial length (AL), corneal curvature, corneal diameter, IOP and IV between the SAC group and the NAC group before operation, except for the LV (p = 0.000). All angle parameters including ACD, ACV, AOD, ARA, TISA and TIA in both groups at 3 months post-surgery were significantly different from the preoperative values (p<0.01). In addition, there were significant differences in all angle parameters between two groups before and after operation (All P< 0.05). Besides, the TISA750 in superior quadrant, ACD and ACV were significantly smaller in the group of SAC than those in the group of NAC 3 months after operation (P = 0.041, 0.001 and 0.002, respectively). Conclusions: Cataract surgery can deepen anterior chamber and increase the width of anterior chamber angle in Chinese subjects, but the ACD and ACV in patients with shallow anterior chamber and narrow angle have not reached the normal level, presumably because the iris root of SAC group inserted more anteriorly than that of NAC group. Phacoemulsification may not completely eliminate the risk of glaucoma in NAC group of people after surgery.

Impact of Cataract Surgery on Filtering Bleb Morphology Identified Via Swept-source 3-dimensional Anterior Segment Optical Coherence Tomography

2019 ◽  
Vol 28 (5) ◽  
pp. 433-439
Author(s):  
Akiko Narita ◽  
Yuki Morizane ◽  
Tomoe Miyake ◽  
Kae Sugihara ◽  
Tomoko Ishikawa ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Cataract Surgery ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Swept Source ◽  
3 Dimensional ◽  
Filtering Bleb

Ciliary muscle dimensions measured by swept-source optical coherence tomography in eyes with primary open-angle glaucoma and healthy eyes

2020 ◽  
Vol 40 (9) ◽  
pp. 2247-2255
Author(s):  
Bachar Kudsieh ◽  
José Ignacio Fernández-Vigo ◽  
Hang Shi ◽  
Lucía De Pablo Gómez de Liaño ◽  
José María Ruiz-Moreno ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Ciliary Muscle ◽  
Optical Coherence ◽  
Open Angle ◽  
Swept Source ◽  
Healthy Eyes

Anterior chamber particles are associated with reduction of intraocular pressure after selective laser trabeculoplasty

2020 ◽  
pp. bjophthalmol-2019-315445
Author(s):  
Alexei N Kulikov ◽  
Dmitrii S Maltsev ◽  
Alina A Kazak ◽  
Maria A Burnasheva
Keyword(s):  
Optical Coherence Tomography ◽  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Open Angle Glaucoma ◽  
Anterior Segment ◽  
Optical Coherence ◽  
Selective Laser Trabeculoplasty ◽  
Cross Sectional ◽  
Laser Trabeculoplasty ◽  
The Mean

PurposeTo study the correlation between intraocular pressure (IOP) reduction and the number of hyper-reflective particles appearing in the anterior chamber following selective laser trabeculoplasty (SLT).Material and methodsIn this prospective interventional study, we included primary open-angle glaucoma patients. All participants received a standardised SLT session, which consisted of 100 pulses of 0.9 mJ over 360°. Anterior segment optical coherence tomography (4×4 mm volume scan, 101 horizontal cross-sectional scans) and applanation tonometry were performed before SLT and 15 min, 1 day, 1 week, 1 month and 3 months after. Particles were counted on cross-sectional scans using a standardised algorithm.ResultsIn this study, we included 25 patients (25 eyes), 14 males and 11 females, with a mean age of 68.9±10.5 and baseline IOP of 21.4±4.5 mm Hg. IOP at month 1 and month 3 after SLT was 18.0±4.0 and 17.4±3.3 mm Hg, respectively. The mean number of anterior chamber particles before and 15 min after SLT was 0.62±0.2 and 7.1±2.0 particles/mm2, respectively (p=0.036). There was a statistically significant correlation between the mean number of anterior chamber particles 15 min after SLT and IOP reduction at 1 month (r=0.62, p=0.03) and 3 months (r=0.71, p=0.01).ConclusionThe number of the anterior chamber particles graded using anterior segment optical coherence tomography after the procedure correlates with the IOP-lowering effect of SLT.

Diode Laser Trabeculoplasty in Patients with Pseudoexfoliative Glaucoma

2013 ◽  
Vol 07 (01) ◽  
pp. 14
Author(s):  
Nikola Babić ◽  
Aleksandar Miljković ◽  
Veljko Andreić ◽  
◽  
◽  
...  
Keyword(s):  
Diode Laser ◽  
Open Angle Glaucoma ◽  
Spot Size ◽  
Open Angle ◽  
Pseudoexfoliative Glaucoma ◽  
Laser Trabeculoplasty ◽  
Significant Difference ◽  
Before And After ◽  
One Year ◽  
A Prospective Study

Aim:A prospective study was carried out to examine the efficacy of diode laser trabeculoplasty (DLT) in the treatment of pseudoexfoliative glaucoma (XFG).Material and Methods:Laser trabeculoplasty was performed by Zeiss VISULAS 532s diode pumped solid state laser on 69 eyes of 40 patients with XFG and primary open-angle glaucoma. Power of 600–1,200 mW was used, with a spot size of 100 microns and a pulse of 0.10 second. One hour before DLT brimonidine 0.1 % was administered and during seven days after the treatment Dexamethasone 1 % was administered. All patients underwent complete ophthalmic evaluation before and at intervals after treatment (seven days, one, three and six months and one year postoperatively). During the follow-up period, patients were treated with the same topical anti-glaucoma medicaments as before diode laser trabeculoplasty.Results:Before treatment in XFG patients mean intraocular pressure (IOP) was 23.7±2.6 mmHg and seven days after DLT it was 16.8 ± 2.1 mmHg that is 26.9 % decrease from the baseline, on day 30 it was 14.3 ± 2.2 mmHg which is 38.3 % decrease from the baseline, after 3 months 13.9 ± 2.4 mmHg (39.0 % decrease from the baseline), after six months 13.8 ± 2.7 mmHg or 39.9 % decrease from the baseline and after one year 15.1 ± 3.1 mmHg that makes 36.3 % decrease from the baseline. No side effects (either objective or subjective) were present in examined patients.Conclusions:There is statistically significant difference between IOP before and after diode laser trabeculoplasty, so it is concluded that diode laser trabeculoplasty is an effective mode of treatment for eyes with open-angle glaucoma especially in patients with XFG.

scholarly journals Evaluation of Outflow StructuresIn Vivoafter the Phacocanaloplasty

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Daiva Paulaviciute-Baikstiene ◽  
Renata Vaiciuliene ◽  
Vytautas Jasinskas ◽  
Ingrida Januleviciene
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Intraocular Pressure ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Anterior Segment ◽  
Open Angle ◽  
Glaucoma Medication ◽  
Postoperative Visual Acuity

Purpose. To evaluate thein vivochanges in Schlemm’s canal (SC) and the trabecular meshwork (TM) in patients with primary open-angle glaucoma (POAG) after phacocanaloplasty using anterior segment optical coherence tomography (AS-OCT).Methods. Ten eyes of nine patients with POAG (6 men and 3 women) who underwent phacocanaloplasty. Preoperative and postoperative visual acuity (VA), intraocular pressure (IOP), and use of glaucoma medications were evaluated. The main outcome measures were the area of SC and TM thickness assessed using AS-OCT before and 12 months after surgery.Results. We found statistically significant reduction in IOP (from 26.4 (8.6) mmHg to 12.9 (2.5) (p<0.05) mmHg), increase in VA from 0.7 (0.4) to 0.9 (0.2), and decrease in glaucoma medication from 2.6 (1.2) to 1.1 (1.3) at 12 months postoperatively. There was a significant increase in the SC area (3081.7 (842.8) μm2versus 5098.8 (1190.5) μm2,p<0.001) and a decrease in mean TM thickness (91.2 (18.6) μm versus 81.3 (15.1) μm,p=0.001) after surgery. We found negative correlations between SC area and IOP before surgery (r=-0.67,p=0.03) and also between SC area before and IOP reduction 12 months after the phacocanaloplasty (r=-0.80,p=0.005).Conclusions. Our results showed statistically significant dilation of SC area and reduction of TM thickness after phacocanaloplasty in POAG patients. The degree of SC expansion was related to the IOP decrease.

Sign in / Sign up

Export Citation Format

Share Document