scholarly journals Tomographic Ultrasound Imaging to Control the Placement of Tension-Free Transobturator Tape in Female Urinary Stress Incontinence

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Charlotte M. Gräf ◽  
Tomas Kupec ◽  
Elmar Stickeler ◽  
Tamme W. Goecke ◽  
Ivo Meinhold-Heerlein ◽  
...  
Keyword(s):  
Ultrasound Imaging ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Transobturator Tape ◽  
Urinary Stress Incontinence ◽  
Tension Free ◽  
Novel Approach ◽  
Tomographic Ultrasound Imaging ◽  
Subjective Cure

Purpose. The objective was to evaluate, by means of tomographic ultrasound imaging (TUI), the reliability of a novel approach for determining the position of the implanted tension-free transobturator tape (TOT). Furthermore, we analyzed the association between the position of the tape at rest and the subjective cure in stress incontinent women.Methods. This retrospective pilot study consists of 32 stress incontinent women, who underwent TOT procedure and routine sonographic control at day 1 postoperatively and at follow-up visit. TUI was applied on the resulting 4D volumes, thereby delivering 9 axial slices with a 4 mm interslice distance starting at the meatus urethrae internus in caudal direction. The reliability of the approach was tested by two examiners. Postoperative and follow-up ultrasound parameters of uncured and cured patients were analyzed.Results. Measurements of the position of the TOT demonstrated high intraclass correlation coefficients. We found minor differences between sonographic parameters at day 1 postoperatively and at follow-up after a median period of 321 days. In cured patients, the position of the tape was measured in a more caudal position than in uncured patients.Conclusions. TUI can be a reliable method for determining the position of the tape. Further studies are needed to evaluate whether the postoperatively determined position can be used as an indicator of future subjective cure.

scholarly journals Validation of a 3D CBCT-based protocol for the follow-up of mandibular condyle remodeling

2020 ◽  
Vol 49 (3) ◽  
pp. 20190364
Author(s):  
Pieter-Jan Verhelst ◽  
Eman Shaheen ◽  
Karla de Faria Vasconcelos ◽  
Fréderic Van der Cruyssen ◽  
Sohaib Shujaat ◽  
...  
Keyword(s):  
Cone Beam Ct ◽  
Intraclass Correlation ◽  
Three Dimensional ◽  
Mandibular Condyle ◽  
Correlation Coefficients ◽  
Micro Ct ◽  
Gonial Angle ◽  
Volume Of Interest ◽  
User Friendly

Objectives: Three-dimensional models of mandibular condyles provide a way for condylar remodeling follow-up. The overall aim was to develop and validate a user-friendly workflow for cone beam CT (CBCT)-based semi-automatic condylar registration and segmentation. Methods: A rigid voxel-based registration (VBR) technique for registration of two post-operative CBCT-scans was tested. Two modified mandibular rami, with or without gonial angle, were investigated as the volume of interest for registration. Inter- and intraoperator reproducibility of this technique was tested on 10 mandibular rami of orthognathic patients by means of intraclass correlation coefficients (ICC’s) and descriptive statistics of the transformation values from the VBR. The difference in reproducibility between the two modified rami was evaluated using a paired t-test (p < 0.05). For the segmentation, eight fresh frozen cadaver heads were scanned with CBCT and micro-CT. These data were used to test the inter- and intraoperator reproducibility (ICC’s) and accuracy (Bland–Altman plot) of a newly designed workflow based on semi-automated contour enhancement. Results: Excellent ICC’s (0.94–0.99) were obtained for the voxel-based registration technique using both modified rami. If the gonial angle was not included in the volume of interest, there was a trend of increased operator error suggested by significant higher interoperator differences in translation values (p = 0,0036). The segmentation workflow proved to be highly reproducible with excellent ICC’s (0.99), low absolute mean volume differences between operators (23.19 mm3), within operators (28.93 mm3) and low surface distances between models of different operators (<0.20 mm). Regarding the accuracy, CBCT-models slightly overestimate the condylar volume compared to micro-CT. Conclusions: This study provides a validated user-friendly and reproducible method of creating three-dimensional-surface models of mandibular condyles out of longitudinal CBCT-scans.

scholarly journals One-Year Stability of Frontoparietal Cognitive Control Network Connectivity in Recent Onset Schizophrenia: A Task-Related 3T fMRI Study

2020 ◽  
Vol 46 (5) ◽  
pp. 1249-1258 ◽  
Author(s):  
Jason Smucny ◽  
Tyler A Lesh ◽  
Vanessa C Zarubin ◽  
Tara A Niendam ◽  
J Daniel Ragland ◽  
...  
Keyword(s):  
Cognitive Control ◽  
Intraclass Correlation ◽  
Functional Decline ◽  
Correlation Coefficients ◽  
Control Network ◽  
Continuous Performance Task ◽  
Course Of Illness ◽  
Recent Onset ◽  
Early Course

Abstract Kraepelinian theory posits that schizophrenia (SZ) is a degenerative disorder that worsens throughout the lifespan. Behavioral studies of cognition have since challenged that viewpoint, particularly in the early phases of illness. Nonetheless, the extent to which cognition remains functionally stable during the early course of illness is unclear, particularly with regard to task-associated connectivity in cognition-related brain networks. In this study, we examined the 1-year stability of the frontoparietal control network during the AX-Continuous Performance Task (AX-CPT) from a new baseline sample of 153 participants scanned at 3T, of which 29 recent onset individuals with SZ and 42 healthy control (HC) participants had follow-up data available for analysis. Among individuals that had both baseline and follow-up data, reduced functional connectivity in SZ was observed between the dorsolateral prefrontal cortex (DLPFC) and superior parietal cortex (SPC) during the high control (B cue) condition. Furthermore, this deficit was stable over time, as no significant time × diagnosis interaction or effects of time were observed and intraclass correlation coefficients were greater than 0.6 in HCs and SZ. Previous 1.5T findings showing stable deficits with no evidence of degeneration in performance or DLPFC activation in an independent SZ sample were replicated. Overall, these results suggest that the neuronal circuitry supporting cognitive control is stably impaired during the early course of illness in SZ across multiple levels of analysis with no evidence of functional decline.

scholarly journals Measuring clinical outcomes in children with pediatric acute-onset neuropsychiatric syndrome: data from a 2–5 year follow-up study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Caroline De Visscher ◽  
Eva Hesselmark ◽  
Daniel Rautio ◽  
Ida Gebel Djupedal ◽  
Maria Silverberg ◽  
...  
Keyword(s):  
Psychiatric Symptoms ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Acute Onset ◽  
Symptom Presentation ◽  
Intraclass Correlation Coefficients ◽  
Follow Up Study ◽  
Functional Measures ◽  
Core Symptoms

Abstract Background It is unclear how to best measure the complex symptom presentation of pediatric acute-onset neuropsychiatric syndrome (PANS). Methods Well-characterized participants of a 2–5 year follow-up study (n = 34; 56% male) underwent clinical evaluations and completed scales assessing global symptom severity, functional impairment and specific psychiatric symptoms. We explored inter-correlations between the measures and used intraclass correlation coefficients to evaluate the agreement between clinician-, parent- and child ratings of the same constructs. Results Ratings on symptom-specific measures varied largely between participants. Agreement between informants was excellent on functional scales, fair-to-moderate on global severity scales and mixed on symptom-specific scales. Clinician-rated global and functional measures had stronger inter-correlations with parent- and child-rated functional measures than with symptom-specific measures. Conclusions General instruments assessing global severity and functioning are well suited for the assessment and follow-up of PANS, but should be complemented by symptom-specific scales representative of core symptoms.

scholarly journals Assessment of a generalizable methodology to assess learning from manikin-based simulation technology*

2014 ◽  
Vol 28 (1) ◽  
pp. 16-20 ◽  
Author(s):  
Dominic A. Giuliano ◽  
Marion McGregor
Keyword(s):  
Learning Outcomes ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Wisdom Of Crowds ◽  
Diverse Range ◽  
Intraclass Correlation Coefficients ◽  
Significant Difference ◽  
Assessment Procedures ◽  
The Impact

Objective This study combined a learning outcomes-based checklist and salient characteristics derived from wisdom-of-crowds theory to test whether differing groups of judges (diversity maximized versus expertise maximized) would be able to appropriately assess videotaped, manikin-based simulation scenarios. Methods Two groups of 3 judges scored 9 videos of interns managing a simulated cardiac event. The first group had a diverse range of knowledge of simulation procedures, while the second group was more homogeneous in their knowledge and had greater simulation expertise. All judges viewed 3 types of videos (predebriefing, postdebriefing, and 6 month follow-up) in a blinded fashion and provided their scores independently. Intraclass correlation coefficients (ICCs) were used to assess the reliability of judges as related to group membership. Scores from each group of judges were averaged to determine the impact of group on scores. Results Results revealed strong ICCs for both groups of judges (diverse, 0.89; expert, 0.97), with the diverse group of judges having a much wider 95% confidence interval for the ICC. Analysis of variance of the average checklist scores indicated no significant difference between the 2 groups of judges for any of the types of videotapes assessed (F = 0.72, p = .4094). There was, however, a statistically significant difference between the types of videos (F = 14.39, p = .0004), with higher scores at the postdebrief and 6-month follow-up time periods. Conclusions Results obtained in this study provide optimism for assessment procedures in simulation using learning outcomes-based checklists and a small panel of judges.

scholarly journals Intra and Inter-rater Reliability between Ultrasound Imaging and Caliper Measures to determine Spring Ligament Dimensions in Cadavers

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Fernando Santiago-Nuño ◽  
Patricia Palomo-López ◽  
Ricardo Becerro-de-Bengoa-Vallejo ◽  
César Calvo-Lobo ◽  
Marta Elena Losa-Iglesias ◽  
...  
Keyword(s):  
Ultrasound Imaging ◽  
Intraclass Correlation ◽  
Correlation Coefficients ◽  
Absolute Accuracy ◽  
Strong Correlations ◽  
Perfect Agreement ◽  
Rater Reliability ◽  
Intraclass Correlation Coefficients ◽  
Spring Ligament ◽  
Good Repeatability

Abstract The purpose was to evaluate intra and inter-rater reliability, repeatability and absolute accuracy between ultrasound imaging (US) and caliper measures to determine Spring ligament (SL) dimensions in cadavers. SLs were identified from 62 human feet from formaldehyde-embalmed cadavers. Intra and inter-observer reliability, repeatability and absolute accuracy of SL width, thickness and length between US and caliper measurements were determined at intra and inter-session by intraclass correlation coefficients, Pearson´s correlation coefficients, Student t tests, standard errors of measurement, minimum detectable changes, values of normality, 95% limits of agreement, and Bland-Altman plots. Excellent inter-session and inter-rater reliability, adequate absolute accuracy, almost perfect agreement and strong correlations were shown for caliper, US and their comparison for all SL dimensions. US measurements presented higher absolute accuracy than caliper measures for SL length and thickness dimensions, while caliper displayed greater absolute accuracy for SL width dimensions. Good repeatability (P > 0.05) was shown for all SL dimensions by US, caliper and their comparison, except for SL width dimension measured with US (P = 0.019). Both US and caliper could be recommended for all SL dimensions evaluation due to their excellent reliability and absolute accuracy in cadavers, although width dimensions should be considered with caution due to US repeatability differences.

scholarly journals Reliability and clinical applicability of a novel tear film imaging tool

2021 ◽  
Author(s):  
Noémi Tóth ◽  
Eszter Szalai ◽  
Tibor Rák ◽  
Veronika Lillik ◽  
Attila Nagy ◽  
...  
Keyword(s):  
Intraclass Correlation ◽  
Tear Film ◽  
Correlation Coefficients ◽  
Kappa Statistics ◽  
Ophthalmological Examination ◽  
Non Invasive ◽  
Imaging Tool ◽  
Clinical Applicability ◽  
Break Up

Abstract Purpose The aim of our research was to investigate the reliability and clinical applicability of a modern tear film imaging tool by comparing the inter- and intragrader difference. The further goal was to compare the non-invasive tear break-up time (NIBUT) measured with the LacryDiag® device with traditional tear film break-up time (TBUT). Methods Comprehensive ophthalmological examination was performed, including LacryDiag® (Quantel Medical, France) (lower tear meniscus height measuring (LTMH), superior and inferior eyelid meibography (MeibS MeibI), interferometry (INT), NIBUT), slit lamp examination, and TBUT. Two independent, well-trained graders selected and analyzed the LTMH, MeibI, MeibS, and INT. The second grader reanalyzed the data 1 month later. Intra- and inter-examiner reliabilities were evaluated using intraclass correlation coefficients (ICC), while for categorical variable, Cohen’s kappa statistics were provided. The Bland-Altman plot was used for visualization of the agreement between measurements. Results Fifty healthy volunteers were examined. For LTMH both the inter- and intragrader variabilities were excellent. Between two graders, the ICC of MeibI was poor; however, between two graders, the ICC of MeibS was good, and the intragrader variability in MeibI and MeibS was excellent. For the INT, both intra- and intergrading were in fair and moderate agreement, although the intragrader agreement was higher. Comparing the NIBUT and TBUT, the agreement was slight. Conclusion Based on our results, examination of a patient during follow-up should be performed by the same examiner, because of the slight agreement. The LacryDiag® is a non-invasive, easy-to-use device, which can examine the tear film and save the recordings for easier follow-up.

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