scholarly journals Random Regret-Minimization Model for Emergency Resource Preallocation at Freeway Accident Black Spots

2018 ◽  
Vol 2018 ◽  
pp. 1-13
Author(s):  
Siliang Luan ◽  
Qingfang Yang ◽  
Wei Wang ◽  
Zhongtai Jiang ◽  
Ruru Xing ◽  
...  
Keyword(s):  
Large Scale ◽  
Traffic Accidents ◽  
Weather Conditions ◽  
Time Cost ◽  
Frequency Method ◽  
Regret Minimization ◽  
Accident Probability ◽  
Black Spots ◽  
Random Regret Minimization

The preallocation of emergency resources is a mechanism increasing preparedness for uncertain traffic accidents under different weather conditions. This paper introduces the concept of accident probability of black spots and an improved accident frequency method to identify accident black spots and obtain the accident probability. At the same time, we propose a three-stage random regret-minimization (RRM) model to minimize the regret value of the attribute of overall response time, cost, and demand, which allocates limited emergency resources to more likely to happen accident spots. Due to the computational complexity of our model, a genetic algorithm is developed to solve a large-scale instance of the problem. A case study focuses on three-year rainy accidents’ data in Weifang, Linyi, and Rizhao of China to test the correctness and validity of the application of the model.

scholarly journals A Bayesian approach to exploring the influence of climate variability modes on fire weather conditions and lightning-ignited wildfires

2021 ◽  
Author(s):  
Bryson C. Bates ◽  
Andrew J. Dowdy ◽  
Lachlan McCaw
Keyword(s):  
Climate Variability ◽  
Network Architecture ◽  
Large Scale ◽  
Weather Prediction ◽  
Weather Conditions ◽  
Fire Weather ◽  
Prescribed Burn ◽  
Data Set ◽  
Climate Modes

AbstractUnderstanding the relationships between large-scale, low-frequency climate variability modes, fire weather conditions and lighting-ignited wildfires has implications for fire-weather prediction, fire management and conservation. This article proposes a Bayesian network framework for quantifying the influence of climate modes on fire weather conditions and occurrence of lightning-ignited wildfires. The main objectives are to describe and demonstrate a probabilistic framework for identifying and quantifying the joint and individual relationships that comprise the climate-wildfire system; gain insight into potential causal mechanisms and pathways; gauge the influence of climate modes on fire weather and lightning-ignition relative to that of local-scale conditions alone; assess the predictive skill of the network; and motivate the use of techniques that are intuitive, flexible and for which user‐friendly software is freely available. A case study illustrates the application of the framework to a forested region in southwest Australia. Indices for six climate variability modes are considered along with two hazard variables (observed fire weather conditions and prescribed burn area), and a 41-year record of lightning-ignited wildfire counts. Using the case study data set, we demonstrate that the proposed framework: (1) is based on reasonable assumptions provided the joint density of the variables is converted to multivariate normal; (2) generates a parsimonious and interpretable network architecture; (3) identifies known or partially known relationships between the variables; (4) has potential to be used in a predictive setting for fire weather conditions; and (5) climate modes are more directly related to fire weather conditions than to lightning-ignition counts.

scholarly journals Characteristics of the 100 largest modern zoonotic disease outbreaks

2021 ◽  
Vol 376 (1837) ◽  
pp. 20200535 ◽  
Author(s):  
Patrick R. Stephens ◽  
N. Gottdenker ◽  
A. M. Schatz ◽  
J. P. Schmidt ◽  
John M. Drake
Keyword(s):  
Disease Surveillance ◽  
Large Scale ◽  
Disease Outbreaks ◽  
Weather Conditions ◽  
Zoonotic Disease ◽  
Global Scale ◽  
Press Freedom ◽  
Quantitative Studies ◽  
Vector Borne

Zoonotic disease outbreaks are an important threat to human health and numerous drivers have been recognized as contributing to their increasing frequency. Identifying and quantifying relationships between drivers of zoonotic disease outbreaks and outbreak severity is critical to developing targeted zoonotic disease surveillance and outbreak prevention strategies. However, quantitative studies of outbreak drivers on a global scale are lacking. Attributes of countries such as press freedom, surveillance capabilities and latitude also bias global outbreak data. To illustrate these issues, we review the characteristics of the 100 largest outbreaks in a global dataset ( n = 4463 bacterial and viral zoonotic outbreaks), and compare them with 200 randomly chosen background controls. Large outbreaks tended to have more drivers than background outbreaks and were related to large-scale environmental and demographic factors such as changes in vector abundance, human population density, unusual weather conditions and water contamination. Pathogens of large outbreaks were more likely to be viral and vector-borne than background outbreaks. Overall, our case study shows that the characteristics of large zoonotic outbreaks with thousands to millions of cases differ consistently from those of more typical outbreaks. We also discuss the limitations of our work, hoping to pave the way for more comprehensive future studies. This article is part of the theme issue ‘Infectious disease macroecology: parasite diversity and dynamics across the globe’.

A Family With Autosomal-Dominant Progressive Sensorineural Hearing Loss

1996 ◽  
Vol 5 (1) ◽  
pp. 23-32 ◽  
Author(s):  
Chris Halpin ◽  
Barbara Herrmann ◽  
Margaret Whearty
Keyword(s):  
Speech Production ◽  
Hearing Aids ◽  
Role Models ◽  
Speech Intelligibility ◽  
Large Scale ◽  
Speech Language Pathology ◽  
The Family ◽  
Patient Will ◽  
Language Pathology

The family described in this article provides an unusual opportunity to relate findings from genetic, histological, electrophysiological, psychophysical, and rehabilitative investigation. Although the total number evaluated is large (49), the known, living affected population is smaller (14), and these are spread from age 20 to age 59. As a result, the findings described above are those of a large-scale case study. Clearly, more data will be available through longitudinal study of the individuals documented in the course of this investigation but, given the slow nature of the progression in this disease, such studies will be undertaken after an interval of several years. The general picture presented to the audiologist who must rehabilitate these cases is that of a progressive cochlear degeneration that affects only thresholds at first, and then rapidly diminishes speech intelligibility. The expected result is that, after normal language development, the patient may accept hearing aids well, encouraged by the support of the family. Performance and satisfaction with the hearing aids is good, until the onset of the speech intelligibility loss, at which time the patient will encounter serious difficulties and may reject hearing aids as unhelpful. As the histological and electrophysiological results indicate, however, the eighth nerve remains viable, especially in the younger affected members, and success with cochlear implantation may be expected. Audiologic counseling efforts are aided by the presence of role models and support from the other affected members of the family. Speech-language pathology services were not considered important by the members of this family since their speech production developed normally and has remained very good. Self-correction of speech was supported by hearing aids and cochlear implants (Case 5’s speech production was documented in Perkell, Lane, Svirsky, & Webster, 1992). These patients received genetic counseling and, due to the high penetrance of the disease, exhibited serious concerns regarding future generations and the hope of a cure.

The Boeing 787 Dreamliner--A case study in large-scale design integration

2008 ◽  
Author(s):  
D. L. McMullin ◽  
A. R. Jacobsen ◽  
D. C. Carvan ◽  
R. J. Gardner ◽  
J. A. Goegan ◽  
...  
Keyword(s):  
Large Scale ◽  
Design Integration ◽  
Scale Design

Disruptive innovation and operationalization in local and sustainable food systems: Examining the University of Toronto-Local Food Plus partnership

2019 ◽  
Vol 6 (1) ◽  
pp. 120-139
Author(s):  
Lori Stahlbrand
Keyword(s):  
Food Systems ◽  
Large Scale ◽  
Food System ◽  
Local Food ◽  
Disruptive Innovation ◽  
Government Support ◽  
Sustainable Food ◽  
University Of Toronto ◽  
The University

This paper traces the partnership between the University of Toronto and the non-profit Local Food Plus (LFP) to bring local sustainable food to its St. George campus. At its launch, the partnership represented the largest purchase of local sustainable food at a Canadian university, as well as LFP’s first foray into supporting institutional procurement of local sustainable food. LFP was founded in 2005 with a vision to foster sustainable local food economies. To this end, LFP developed a certification system and a marketing program that matched certified farmers and processors to buyers. LFP emphasized large-scale purchases by public institutions. Using information from in-depth semi-structured key informant interviews, this paper argues that the LFP project was a disruptive innovation that posed a challenge to many dimensions of the established food system. The LFP case study reveals structural obstacles to operationalizing a local and sustainable food system. These include a lack of mid-sized infrastructure serving local farmers, the domination of a rebate system of purchasing controlled by an oligopolistic foodservice sector, and embedded government support of export agriculture. This case study is an example of praxis, as the author was the founder of LFP, as well as an academic researcher and analyst.

Algorithm of combining chromatography mass spectrometry-untargeted profiling and multivariate analysis for identification of marker-substances in samples of complex composition

2020 ◽  
Vol 86 (7) ◽  
pp. 12-19
Author(s):  
I. V. Plyushchenko ◽  
D. G. Shakhmatov ◽  
I. A. Rodin
Keyword(s):  
Mass Spectrometry ◽  
Multivariate Analysis ◽  
Large Scale ◽  
Complex Composition ◽  
Unified Protocol ◽  
Chromatography Mass Spectrometry ◽  
Marker Substances ◽  
Selection Testing ◽  
Untargeted Profiling

A viral development of statistical data processing, computing capabilities, chromatography-mass spectrometry, and omics technologies (technologies based on the achievements of genomics, transcriptomics, proteomics, metabolomics) in recent decades has not led to formation of a unified protocol for untargeted profiling. Systematic errors reduce the reproducibility and reliability of the obtained results, and at the same time hinder consolidation and analysis of data gained in large-scale multi-day experiments. We propose an algorithm for conducting omics profiling to identify potential markers in the samples of complex composition and present the case study of urine samples obtained from different clinical groups of patients. Profiling was carried out by the method of liquid chromatography mass spectrometry. The markers were selected using methods of multivariate analysis including machine learning and feature selection. Testing of the approach was performed using an independent dataset by clustering and projection on principal components.

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