scholarly journals An Ontology-Based Artificial Intelligence Model for Medicine Side-Effect Prediction: Taking Traditional Chinese Medicine as an Example

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Yuanzhe Yao ◽  
Zeheng Wang ◽  
Liang Li ◽  
Kun Lu ◽  
Runyu Liu ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Prediction Model ◽  
Side Effect ◽  
Treatment Model ◽  
Proposed Model ◽  
Main Components

In this work, an ontology-based model for AI-assisted medicine side-effect (SE) prediction is developed, where three main components, including the drug model, the treatment model, and the AI-assisted prediction model, of the proposed model are presented. To validate the proposed model, an ANN structure is established and trained by two hundred forty-two TCM prescriptions. These data are gathered and classified from the most famous ancient TCM book, and more than one thousand SE reports, in which two ontology-based attributions, hot and cold, are introduced to evaluate whether the prescription will cause SE or not. The results preliminarily reveal that it is a relationship between the ontology-based attributions and the corresponding predicted indicator that can be learnt by AI for predicting the SE, which suggests the proposed model has a potential in AI-assisted SE prediction. However, it should be noted that the proposed model highly depends on the sufficient clinic data, and hereby, much deeper exploration is important for enhancing the accuracy of the prediction.

scholarly journals Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine

2019 ◽  
Vol 4 (4) ◽  
pp. 71
Author(s):  
Junjie Zhang ◽  
Qingning Su ◽  
William G. Loudon ◽  
Katherine L. Lee ◽  
Jane Luo ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Holistic Approach ◽  
Medical Intervention ◽  
Learning Technology ◽  
Lifestyle Behaviors ◽  
Breathing Patterns ◽  
Current State ◽  
Score Index

Rising concerns about the short- and long-term detrimental consequences of administration of conventional pharmacopeia are fueling the search for alternative, complementary, personalized, and comprehensive approaches to human healthcare. Qigong, a form of Traditional Chinese Medicine, represents a viable alternative approach. Here, we started with the practical, philosophical, and psychological background of Ki (in Japanese) or Qi (in Chinese) and their relationship to Qigong theory and clinical application. Noting the drawbacks of the current state of Qigong clinic, herein we propose that to manage the unique aspects of the Eastern ‘non-linearity’ and ‘holistic’ approach, it needs to be integrated with the Western “linearity” “one-direction” approach. This is done through developing the concepts of “Qigong breathing signatures,” which can define our life breathing patterns associated with diseases using machine learning technology. We predict that this can be achieved by establishing an artificial intelligence (AI)-Medicine training camp of databases, which will integrate Qigong-like breathing patterns with different pathologies unique to individuals. Such an integrated connection will allow the AI-Medicine algorithm to identify breathing patterns and guide medical intervention. This unique view of potentially connecting Eastern Medicine and Western Technology can further add a novel insight to our current understanding of both Western and Eastern medicine, thereby establishing a vitality score index (VSI) that can predict the outcomes of lifestyle behaviors and medical conditions.

scholarly journals A 5-Year Survival Prediction Model for Chronic Heart Failure Patients Induced by Coronary Heart Disease with Traditional Chinese Medicine Intervention

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Hui Guan ◽  
Guo-Hua Dai ◽  
Wu-Lin Gao ◽  
Xue Zhao ◽  
Zhen-Hao Cai ◽  
...  
Keyword(s):  
Heart Failure ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Chinese Medicine ◽  
Chronic Heart Failure ◽  
Traditional Chinese Medicine ◽  
Prediction Model ◽  
Protective Factor ◽  
Survival Prediction ◽  
Training Set

Objective. This study aimed to construct a 5-year survival prediction model of coronary heart disease (CHD) induced chronic heart failure (CHF), which is supported by the traditional Chinese medicine (TCM) factor, and to verify the model. Methods. Inpatients from January 1, 2012, to December 31, 2017, in seven hospitals in Shandong Province were studied. The random number table was used to randomly divide the seven hospitals into two groups (training set and verification set). In the training set, the least absolute shrinkage selection operator regression was first used to screen the independent variables. Logistic regression was then applied to construct a survival prediction model. The following nomogram visualizes the prediction model results. Finally, C-indices, calibration curves, and decision curves were used to discriminate and calibrate the established model and evaluate its practicability in the clinic. Bootstrap resampling and the verification set were used for internal and external verification, respectively. Results. A total of 424 eligible patients were included in the model construction and verification. In this 5-year survival prediction model of patients with CHF induced by CHD, eight independent predictors were included. The series of C-indices for the training set, bootstrap resamples, and verification set was 0.885, 0.867, and 0.835, respectively, demonstrating the credibility of our model. Additionally, the receiver operating characteristic curve, calibration curve, and clinical decision curve analysis of the training and verification sets showed that this 5-year survival prediction model was good in discrimination, calibration, and clinical practicability. Conclusion. This work highlights eight independent factors affecting 5-year mortality in patients with CHF induced by CHD after discharge and further helps reallocate medical resources rationally by precisely identifying high-risk groups. The constructed prediction model not only plays a credible role in prediction but also demonstrates TCM intervention as a protective factor for the 5-year death of patients with CHF induced by CHD, thereby advancing the use of TCM in CHF.

The Impact of Artificial Intelligence on Traditional Chinese Medicine

2021 ◽  
pp. 1-18
Author(s):  
Yulin Wang ◽  
Xiuming Shi ◽  
Li Li ◽  
Thomas Efferth ◽  
Dong Shang
Keyword(s):  
Artificial Intelligence ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Modern Science ◽  
Diagnostic Methods ◽  
Digital Data ◽  
Syndrome Differentiation ◽  
Efficacy Evaluation ◽  
Combination Rules ◽  
The Impact

Traditional Chinese Medicine (TCM) is a well-established medical system with a long history. Currently, artificial intelligence (AI) is rapidly expanding in many fields including TCM. AI will significantly improve the reliability and accuracy of diagnostics, thus increasing the use of effective therapeutic methods for patients. This systematic review provides an updated overview on the major breakthroughs in the field of AI-assisted TCM four diagnostic methods, syndrome differentiation, and treatment. AI-assisted TCM diagnosis is mainly based on digital data collected by modern electronic instruments, which makes TCM diagnosis more quantitative, objective, and standardized. As a result, the diagnosis decisions made by different TCM doctors exhibit more consistency, accuracy, and reliability. Meanwhile, the therapeutic efficacy of TCM can be evaluated objectively. Therefore, AI is promoting TCM from experience to evidence-based medicine, a genuine scientific revolution. Furthermore, huge and non-uniform knowledge on formula-syndrome relationships and the combination rules of herbal TCM formulae could be better standardized with the help of AI analysis, which is necessary for the clinical efficacy evaluation and further optimization on the standardized TCM formulae. AI bridges the gap between TCM and modern science and technology. AI may bring clinical TCM diagnostics closer to western medicine. With the help of AI, more scientific evidence about TCM will be discovered. It can be expected that more unified guidelines for specific TCM syndromes will be issued with the development of AI-assisted TCM therapies in the future.

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