scholarly journals The Utility of Immunohistochemistry in Differentiating Metastatic Primary Squamous Cell Carcinoma of the Thyroid from a Primary Lung Squamous Cell Carcinoma

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Nern Hoong Kao ◽  
Chien Sheng Tan ◽  
Adrian Jit Hin Koh
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Tumour ◽  
Lung Squamous Cell Carcinoma ◽  
Anaplastic Thyroid Carcinoma ◽  
Primary Site ◽  
Primary Squamous Cell Carcinoma ◽  
Diagnostic Challenge

Primary squamous cell carcinoma of the thyroid gland (PSCCTh) and anaplastic thyroid carcinoma with extensive squamous differentiation are rare entities which pose a diagnostic challenge in determining the primary site when presented as metastases. The difficulty in confirming a thyroid primary is further compounded by the aggressive nature of these tumours which frequently present at advanced stages. We present a case in which the patient presented with a thyroid mass and a lung mass simultaneously. The risk of misinterpreting the site of primary tumour as lung is greatly increased because squamous cell carcinoma of lung is much more common than its thyroid counterpart. This case highlights the effectiveness of PAX-8 stain in determining the primary site of tumour when squamous cell carcinoma is found in both lung and thyroid gland.

A Case of Primary Squamous Cell Carcinoma of the Thyroid Gland

2005 ◽  
Vol 20 (1) ◽  
pp. 84 ◽  
Author(s):  
Kyung Im Bae ◽  
Ki Hun Kim ◽  
Sung Yeun Yang ◽  
Soon Hee Lee ◽  
Su Kyoung Kwon ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma

scholarly journals Primary squamous cell carcinoma of the thyroid gland

2014 ◽  
Vol 2014 (12) ◽  
pp. rju133-rju133 ◽  
Author(s):  
K. Sapalidis ◽  
I. Anastasiadis ◽  
N. Panteli ◽  
T.-M. Strati ◽  
L. Liavas ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma

scholarly journals Primary squamous cell carcinoma of the thyroid gland.

1985 ◽  
Vol 36 (4) ◽  
pp. 396-405
Author(s):  
Mitsutake Tani ◽  
Mutsuo Amatsu ◽  
Noriaki Tsubota ◽  
Ryuta Aogauchi ◽  
Kuniyuki Yamamoto
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma

scholarly journals Primary Squamous Cell Carcinoma of the Thyroid Gland

2003 ◽  
Vol 168 (2) ◽  
pp. 124-125 ◽  
Author(s):  
Peter W. Zimmer ◽  
David Wilson ◽  
Norman Bell
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma

Primary squamous cell carcinoma of the thyroid gland —A case report

1985 ◽  
Vol 15 (1) ◽  
pp. 60-62 ◽  
Author(s):  
V. K. Kapoor ◽  
D. Sharma ◽  
A. K. Mukhopadhyay ◽  
T. K. Chattopadhyay
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Primary Squamous Cell Carcinoma

scholarly journals A Case of Primary Squamous Cell Carcinoma of The Thyroid Gland

2021 ◽  
Vol 37 (2) ◽  
pp. 91-95
Author(s):  
Sihyung Kang ◽  
Gi Cheol Park
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Neck Mass ◽  
Rapid Progression ◽  
Selective Neck Dissection ◽  
Primary Squamous Cell Carcinoma ◽  
Aggressive Clinical Course ◽  
Painful Neck

Primary squamous cell carcinoma of thyroid is a very rare malignant tumor with poor prognosis. It is usually diagnosed as an advanced disease infiltrating adjacent organs, and characterized by aggressive clinical course with an average postoperative survival time of less than 1 year. Recently, we had a 79- year-old woman with a painful neck mass who was diagnosed as primary squamous cell carcinoma of thyroid gland. She underwent total thyroidectomy and selective neck dissection(level Ⅲ, Ⅵ) with no further postoperative managements such as radiation therapy or chemotherapy; she died of poor general condition and pneumonia resulting from rapid progression of the lesion on the 38th day after surgery. We report this case with a review of relevant literatures.

scholarly journals Primary squamous cell carcinoma of the thyroid-case report of a rare disease

2020 ◽  
Vol 4 (2) ◽  
pp. 01-04
Author(s):  
Lévay Bernadett
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vocal Cord Palsy ◽  
Neck Mass ◽  
Primary Squamous Cell Carcinoma ◽  
Adequate Treatment ◽  
Disease Case

Introduction: Primary squamous cell carcinoma (SCC) of the thyroid gland is a very rare entity. The prognosis is very poor with a short survival time. The aim of this article is to report a case of a SCC of the thyroid gland in a 68-year-old woman, emphasizing how complicate is the operation and the adequate treatment of this disease. Case Report: A 68-year -old woman presented with rapidly growing neck mass with hoarseness and compressive symptoms. Physical examination revealed a hard fixed tumor with right sided vocal cord palsy. Histopathological result confirmed the diagnosis of SCC of the thyroid. PET/CT scan excluded the possibility of other primary malignancies. A surgical intervention was performed, however the patient died in the middle of the palliative radiation therapy. Conclusion: SCC of the thyroid gland is a great challenge for the surgeon and also for the multidisciplinary team to come up with the best treatment option which is suitable for the patient due to its unfavorable prognosis.

Squamous cell carcinoma of the thyroid gland: primary or secondary disease?

2010 ◽  
Vol 125 (1) ◽  
pp. 3-9 ◽  
Author(s):  
M I Syed ◽  
M Stewart ◽  
S Syed ◽  
S Dahill ◽  
C Adams ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Thyroid Gland ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
English Language ◽  
Primary Tumour ◽  
Treatment Options ◽  
Supportive Therapy ◽  
Secondary Disease ◽  
Therapy Treatment

AbstractObjective:To review the aetiopathogenesis, clinical characteristics, immunohistochemical profile, prognosis and treatment options for primary thyroid squamous cell carcinoma, and to compare it with squamous cell carcinoma metastatic to the thyroid, thus providing the reader with a framework for differentiating primary and secondary disease.Method:Review of English language literature from the past 25 years.Search strategy:A search of the Medline, Embase and Cochrane databases (April 1984 to April 2009) was undertaken to enable a comprehensive review.Results:After applying strict criteria for the diagnosis of primary thyroid squamous cell carcinoma, 28 articles were identified reporting 84 cases. When reviewing secondary thyroid squamous cell carcinoma, we only analysed cases of squamous cell carcinoma metastatic to the thyroid gland, and found 28 articles reporting 78 cases.Conclusion:It is possible to differentiate between primary and secondary thyroid squamous cell carcinoma, on the basis of combined evidence from clinical examination and endoscopic, pathological and radiological evaluation. Such differentiation is important, as the prognosis for primary squamous cell carcinoma is uniformly poor irrespective of treatment, and the most suitable option may be supportive therapy. Treatment for secondary squamous cell carcinoma of the thyroid varies with the site and extent of spread of the primary tumour.

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