Monochorionic Triplet Gestation after Single Blastocyst Transfer Using Donor Oocytes: Case Report and Review

We report a case of a 43-year-old patient with a monochorionic triamniotic triplet pregnancy after IVF with donor oocytes. After failed IVF attempts, the patient chose to undergo treatment with donor oocytes. Her 22-year-old oocyte donor underwent standard controlled ovarian hyperstimulation. The retrieved oocytes were fertilized in vitro, and one embryo was transferred at the blastocyst stage. At 6 weeks and 5 days of gestation, an ultrasound revealed monochorionic triamniotic (MCTA) triplets. The risk of monozygotic twinning in women undergoing in vitro fertilization (IVF) is reported to be higher than that in natural conception, although the causes of the phenomenon have not yet been clarified. Efforts still must be made in order to prevent monozygotic multiple pregnancies, associated with much greater chances of obstetric and perinatal morbidity and mortality.

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Stage 2 Acupuncture for Poor Ovarian Response: A Randomized Controlled Trial

Journal of Clinical Medicine ◽

10.3390/jcm10102182 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2182

Author(s):

Jihyun Kim ◽

Hoyoung Lee ◽

Tae-Young Choi ◽

Joong Il Kim ◽

Byoung-Kab Kang ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Controlled Trial ◽

Ovarian Response ◽

Controlled Ovarian Hyperstimulation ◽

University Hospital ◽

Ovarian Hyperstimulation ◽

Poor Ovarian Response ◽

Vitro Fertilization ◽

Randomized Controlled

Acupuncture is believed to improve ovarian reserve and reproductive outcomes in women undergoing in vitro fertilization (IVF). This study was conducted to evaluate the effect of network-optimized acupuncture followed by IVF on the oocyte yield in women showing a poor ovarian response. This study was an exploratory randomized controlled trial conducted from June 2017 to January 2020 at the Pusan National University Hospital. Women diagnosed with poor ovarian response were enrolled and randomly divided into two groups: IVF alone and Ac + IVF groups (16 acupuncture sessions before IVF treatment). Eight acupoints with high degree centrality and betweenness centrality were selected using network analysis. Among the participants, compared with the IVF treatment alone, the acupuncture + IVF treatment significantly increased the number of retrieved mature oocytes in women aged more than 37 years and in those undergoing more than one controlled ovarian hyperstimulation cycle. The negative correlation between the number of retrieved mature oocytes and consecutive controlled ovarian hyperstimulation cycles was not observed in the Ac + IVF group irrespective of the maternal age. These findings suggest that physicians can consider acupuncture for the treatment of women with poor ovarian response and aged > 37 years or undergoing multiple IVF cycles.

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For women undergoing in vitro fertilization (IVF) with poor response to controlled ovarian hyperstimulation (COH), how do different protocols for pituitary downregulation compare?

Cochrane Clinical Answers ◽

10.1002/cca.3124 ◽

2020 ◽

Author(s):

Sera Tort ◽

Jane Burch

Keyword(s):

In Vitro Fertilization ◽

Poor Response ◽

Controlled Ovarian Hyperstimulation ◽

Ovarian Hyperstimulation ◽

Vitro Fertilization ◽

Pituitary Downregulation

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Pregnancy Outcomes Using Assisted Reproductive Technology After Fertility-Preserving Therapy in Patients With Endometrial Adenocarcinoma or Atypical Complex Hyperplasia

International Journal of Gynecological Cancer ◽

10.1111/igc.0b013e31819960ba ◽

2009 ◽

Vol 19 (1) ◽

pp. 147-151 ◽

Cited By ~ 23

Author(s):

Aera R. Han ◽

Yong-Soon Kwon ◽

D. Y. Kim ◽

J. H. Kim ◽

Y. M. Kim ◽

...

Keyword(s):

Endometrial Cancer ◽

Assisted Reproductive Technology ◽

Intrauterine Insemination ◽

Medical Center ◽

Endometrial Adenocarcinoma ◽

Controlled Ovarian Hyperstimulation ◽

Reproductive Technology ◽

Vitro Fertilization ◽

Asan Medical

Objectives:To evaluate the outcomes of pregnancy in young women (<40 years old) with early endometrial cancer or atypical complex hyperplasia who were treated by conservative management followed by assisted reproductive technology (ART).Materials and Methods:Medical charts of 11 patients treated from January 1997 to October 2007 at Asan Medical Center were retrospectively reviewed. These patients had all been treated with progestin and serial dilatation and curettage as primary fertility-preserving therapies.Results:After pathological remission of disease, 10 patients tried to become pregnant by ART, 4 by in vitro fertilization and embryo transfer, and 6 by controlled ovarian hyperstimulation, with or without intrauterine insemination. Eight women had intrauterine pregnancies, and 6 patients had live births. Patients have been followed up for 9 to 51 months (mean, 21 months) after delivery, with no evidence of tumor recurrence.Conclusions:Fertility-preserving therapy followed by ART can be a good option in well-selected patients with early endometrial cancer who want to become pregnant.

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