scholarly journals Gradenigo’s Syndrome with Carotid Septic Stenosis

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Ana Sousa Menezes ◽  
Daniela Ribeiro ◽  
Filipa Balona ◽  
Ricardo Maré ◽  
Cátia Azevedo ◽  
...  
Keyword(s):  
Otitis Media ◽  
Internal Carotid ◽  
Sinus Thrombosis ◽  
Abducens Nerve ◽  
Pediatric Case ◽  
Suppurative Otitis Media ◽  
Gradenigo’S Syndrome ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
Clinical Triad

Gradenigo’s syndrome was firstly described in 1907 by Giusseppe Gradenigo and is defined as the clinical triad of suppurative otitis media, ipsilateral abducens nerve palsy, and pain in the distribution of the first and the second branches of the trigeminal nerve. Since the advent of antibiotics, the incidence of this potentially life-threatening complication has diminished, but occasional cases still occur. We herein report a pediatric case of otitis media associated with Gradenigo’s syndrome complicated by ipsilateral septic cavernous sinus thrombosis and infectious arteritis of the internal carotid artery.

Lateral sinus thrombosis following myringoplasty: a rare complication

2012 ◽  
Vol 127 (S1) ◽  
pp. S39-S41 ◽  
Author(s):  
G Sim ◽  
F Lannigan
Keyword(s):  
Case Report ◽  
Mortality Rate ◽  
Otitis Media ◽  
High Mortality ◽  
Sinus Thrombosis ◽  
Rare Complication ◽  
Lateral Sinus ◽  
Lateral Sinus Thrombosis ◽  
Life Threatening ◽  
Life Threatening Complication

AbstractObjective:We report lateral sinus thrombosis occurring as a rare complication following a routine and uneventful otological procedure.Case report:Lateral sinus thrombosis is a rare but known complication of otitis media. It has not been documented as a complication of routine otological surgery. We present a case of this rare complication following a myringoplasty. We also discuss the presentation, investigation and treatment of lateral sinus thrombosis. It is essential to be able to recognise and treat this rare complication early, due to its high mortality rate.Conclusion:Lateral sinus thrombosis is a rare but potentially life-threatening complication. It is therefore essential for clinicians to be able to recognise and treat this condition early.

scholarly journals Gradenigo’s Syndrome and Labyrinthitis: Conservative versus Surgical Treatment

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Ahmad Al-juboori ◽  
Amira Nasser Al Hail
Keyword(s):  
Conservative Treatment ◽  
Otitis Media ◽  
Severe Pain ◽  
Antimicrobial Agents ◽  
Petrous Bone ◽  
Sixth Cranial Nerve ◽  
Suppurative Otitis Media ◽  
Gradenigo’S Syndrome ◽  
Signal Changes ◽  
Clinical Triad

Background. Extracranial intratemporal complications of chronic suppurative otitis media (CSOM) are extremely rare. Gradenigo’s syndrome is defined as a clinical triad of otitis media, severe pain originating from the trigeminal nerve, and ipsilateral sixth cranial nerve palsy. Case Report. A 61-year-old man presented with chronic left ear discharge, left-sided headache, diplopia associated with vertigo, tinnitus, and hearing impairment. MRI with contrast showed asymmetrical signal changes in the bilateral petrous bone with reduced enhancement on the left with high suspicion of petrositis; in the context of chronic tympanomastoiditis, there was a 10 × 4 mm enhancing lesion in the left internal auditory meatus involving the 7th-8th nerve complex. The patient was treated conservatively with local and systemic antimicrobial agents, he had satisfactory response and improvement regarding symptoms of ear discharge, vertigo, and diplopia, but there is no remarkable response regarding hearing loss and tinnitus. Conclusion. Although there is little evidence to support the use of conservative treatment in the treatment of Gradenigo’s syndrome resulting from chronic ear disease, we here demonstrate successful conservative treatment of Gradenigo’s syndrome.

scholarly journals Sigmoid Sinus Thrombosis as a Complication of Acute Otitis Media in a 6-Year-Old Male

2021 ◽  
pp. 014556132110157
Author(s):  
Alexandros Poutoglidis ◽  
Nikolaos Tsetsos ◽  
Stergiani Keramari ◽  
Ioannis Skoumpas ◽  
Konstantinos Vlachtsis ◽  
...  
Keyword(s):  
Otitis Media ◽  
Pediatric Patients ◽  
Sinus Thrombosis ◽  
Wide Spectrum ◽  
Acute Otitis Media ◽  
Sigmoid Sinus ◽  
Cortical Mastoidectomy ◽  
Life Threatening ◽  
Life Threatening Complication ◽  
High Index Of Suspicion

Sigmoid sinus thrombosis (SST) is a potentially life-threatening complication of otitis media which is nowadays rare due to the widespread use of antibiotics. A high index of suspicion is necessary to allow for a timely diagnostic and therapeutic intervention. Intravenous wide-spectrum antibiotics and a cortical mastoidectomy are the mainstay of treatment. There is no consensus regarding the necessity of anticoagulants in pediatric patients. We present a 6-year-old boy who presented with an SST as a result of acute otitis media.

Gradenigo’s and Vernet’s syndrome in an adult man with Candida mastoiditis

2021 ◽  
Vol 14 (4) ◽  
pp. e241006
Author(s):  
Maria A Parekh ◽  
Vitor H Pacheco
Keyword(s):  
Otitis Media ◽  
Cranial Nerve ◽  
Acute Otitis Media ◽  
Jugular Foramen ◽  
Cranial Neuropathy ◽  
Gradenigo’S Syndrome ◽  
Adjacent Structures ◽  
Life Threatening ◽  
Clinical Triad ◽  
Apical Petrositis

The authors report a case of fungal otitis media complicated by extension of the infection into adjacent structures causing apical petrositis and subsequently involvement of the jugular foramen in a 71-year-old diabetic man. First described in 1907, Gradenigo’s syndrome is a serious but rare clinical triad of acute otitis media, unilateral pain in the distribution of cranial nerve V (trigeminal) and ipsilateral cranial nerve VI (abducens) palsy that commonly presents without all three features and is therefore often missed. In this report, our patient was initially misdiagnosed as having a diabetic cranial neuropathy, and later he developed Vernet’s syndrome. Despite aggressive surgical and medical management, he did poorly and died a few weeks later. Clinicians need to be aware of this serious and life-threatening complication of otitis media in high-risk individuals with diabetes or immunocompromised states, to allow early diagnosis and improved clinical outcomes.

scholarly journals Acute otitis media associated with Gradenigo syndrome and transverse sinus thrombosis: a case report

2019 ◽  
Vol 47 (3) ◽  
pp. 1348-1352 ◽  
Author(s):  
Sercan Özkaçmaz
Keyword(s):  
Otitis Media ◽  
Sinus Thrombosis ◽  
Neurological Complication ◽  
Acute Otitis Media ◽  
Abducens Nerve ◽  
Transverse Sinus ◽  
Cerebral Venous Sinus Thrombosis ◽  
Petrous Apex ◽  
Pediatric Case ◽  
Middle Ear Infection

Gradenigo syndrome is associated with middle ear infection that extends to the petrous apex, leading to pain at the innervation site of the ophthalmic and maxillary branches of the trigeminal nerve and the development of abducens nerve palsy. Cerebral venous sinus thrombosis is a serious neurological complication of otitis media and occurs secondary to spread of the infection to the underlying bone. We herein report a pediatric case of otitis media associated with Gradenigo syndrome and ipsilateral sigmoid–transverse sinus thrombosis with magnetic resonance imaging findings.

Diplopia in a Child: Gradenigo Syndrome Is an Unforgettable Disease

2021 ◽  
pp. 014556132198945
Author(s):  
Kai-Chieh Chan ◽  
Shih-Lung Chen
Keyword(s):  
Differential Diagnosis ◽  
Otitis Media ◽  
Nerve Palsy ◽  
Abducens Nerve ◽  
Modern Society ◽  
Abducens Nerve Palsy ◽  
Suppurative Otitis Media ◽  
Orbital Pain ◽  
Clinical Triad ◽  
Apical Petrositis

Gradenigo syndrome is a clinical triad of abducens nerve palsy, retro-orbital pain (trigeminal ganglionitis), and chronic otorrhea (otitis media). The etiology of Gradenigo syndrome results from apical petrositis secondary to suppurative otitis media. Although apical petrositis has gradually become uncommon in modern society due to the widespread use of antibiotics, Gradenigo syndrome should be considered in the differential diagnosis of a child’s diplopia.

Abducens nerve palsy as the sole presenting symptom of petrous apicitis

2002 ◽  
Vol 116 (9) ◽  
pp. 726-729 ◽  
Author(s):  
T. Price ◽  
G. Fayad
Keyword(s):  
Otitis Media ◽  
Facial Pain ◽  
Nerve Palsy ◽  
Abducens Nerve ◽  
Fatal Complication ◽  
Suppurative Otitis Media ◽  
Abducens Paralysis ◽  
Delayed Recognition ◽  
Petrous Apicitis ◽  
Reliable Sign

Petrous apicitis as a potentially fatal complication of suppurative otitis media presents in a variety of forms. Gradenigo’s triad of abducens paralysis, deep facial pain due to trigeminal involvement and acute suppurative otitis media rarely occurs. The conflicting symptoms reported in the literature usually result in the delayed recognition of the condition with potentially disastrous consequences. The VIth nerve palsy is considered to be the least reliable sign as it is least often present. We present a case in which it was the sole presenting symptom.

scholarly journals Demography, types, outcome and relationship of surgically treated intracranial suppuration complicating chronic suppurative otitis media and bacterial rhinosinusitis

2014 ◽  
Vol 05 (S 01) ◽  
pp. S048-S052 ◽  
Author(s):  
Olufemi Emmanuel Idowu ◽  
Vincent A. Adekoya ◽  
Adesegun P. Adeyinka ◽  
Bogofanyo K. Beredugo-Amadasun ◽  
Olawale O. Olubi
Keyword(s):  
Confidence Interval ◽  
Otitis Media ◽  
Rare Complication ◽  
Chronic Suppurative Otitis Media ◽  
Optimal Outcome ◽  
Suppurative Otitis Media ◽  
Radiological Features ◽  
Life Threatening ◽  
Relationship Of ◽  
Intracranial Suppuration

ABSTRACT Introduction: Surgically treated intracranial suppurations (ICS) are uncommon, life-threatening neurosurgical emergencies. They can result from complication of chronic suppurative otitis media (CSOM) and bacterial rhinosinusitis (BRS). The objective of this study was to know the frequency of BRS and CSOM and relate it to its rare complication of surgically treated ICS while also describing the demography, type and outcome of ICS that resulted from BRS and CSOM. Materials and Methods: All patients that presented to the Otorhinolaryngological department and Neurosurgical unit of the same institution with clinical and radiological features of CSOM, BRS, and ICS were prospectively studied over a 5-year period. Patients were followed up for a minimum of 3 months. Results: Two thousand, two hundred and seventy-nine patients presented during the 5-year study period. Of all these patients, 1511 had CSOM (66.3%) and 768 (33.7%) presented with features of BRS. Eleven (0.73%) had ICS complicating their CSOM while 8 (1.04%) cases of surgically treated ICS followed BRS. Bacterial rhinosinusitis was not more likely to lead to ICS (P = 0.4348). The Odds ratio (OR) of a child ≤ 18 years of age with CSOM developing ICS was 5.24 (95% Confidence interval 1.13-24.34; P = 0.0345), while it was 7.60 (95% Confidence interval 1.52-37.97; P = 0.0134) for children with BRS. Conclusions: The most common type of ICS complicating CSOM and BRS was brain abscess and subdural empyema, respectively. Children are more prone to develop surgical ICS following CSOM and BRS. The proportion of males that had ICS was higher in both CSOM and BRS patients. Optimal outcome is achieved in patients that presented with GCS of 13 and above.

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