scholarly journals Salivary Duct Carcinoma: Case Reports and Brief Review of the Literature

2021 ◽  
Vol 2021 ◽  
pp. 1-4
Author(s):  
Deepti Kantamani ◽  
Sai S. Bandaru ◽  
Jennifer L. Miatech ◽  
M. Patrick Stagg
Keyword(s):  
Neck Dissection ◽  
Adjuvant Radiotherapy ◽  
Case Reports ◽  
Salivary Duct Carcinoma ◽  
World Health ◽  
High Morbidity ◽  
Adjuvant Radiation ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Total Parotidectomy

Salivary duct carcinoma (SDC) is an uncommon and highly aggressive tumor associated with high morbidity and mortality. According to the World Health Organization, it is an extremely rare malignancy with an estimated incidence of 1-1.2 in 1,000,000 patients. Standard treatment for SDC is wide surgical resection along with lymph node dissection followed by adjuvant radiation therapy. The role of adjuvant chemotherapy is not known. In this report, we present three cases of SDC. A 71-year-old female with T1N0M0 disease was treated with total parotidectomy, ipsilateral neck dissection, and adjuvant radiotherapy without evidence of disease recurrence at 5 months. The second is a 59-year-old female with TXN1M0 disease who was treated with total parotidectomy with ipsilateral level I-IV neck dissection and adjuvant radiotherapy without evidence of disease occurrence at 21 months. The third case is a 79-year-old male with widely metastatic disease, including brain metastases, treated with cranial irradiation, leuprolide, and lapatinib who remains under home hospice care.

Management of sarcomatoid salivary duct carcinoma of the submandibular gland duct with coexisting seropositive human immunodeficiency virus

2013 ◽  
Vol 127 (6) ◽  
pp. 621-624
Author(s):  
W F Mourad ◽  
K S Hu ◽  
R A Shourbaji ◽  
L B Harrison
Keyword(s):  
Computed Tomography ◽  
Submandibular Gland ◽  
Adjuvant Radiotherapy ◽  
Salivary Duct Carcinoma ◽  
Emission Tomography ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Positron Emission ◽  
Immunodeficiency Virus ◽  
Gland Duct

AbstractBackground:Sarcomatoid salivary duct carcinoma of the submandibular gland is extremely rare. This paper highlights the impact of surgery and adjuvant radiation therapy on the outcome of this disease.Methods:A 59-year-old man with human immunodeficiency virus presented with a painless, rapidly growing left neck mass. Biopsy followed by surgical excision of the left submandibular gland revealed sarcomatoid salivary duct carcinoma of the submandibular gland duct with perineural invasion and close margins, for which he underwent adjuvant radiotherapy. Post-operative positron emission tomography and computed tomography revealed no residual or metastatic disease. Pathological analysis of tumour–node–metastasis staging revealed a T2 N0 M0 (stage II) tumour.Results:The patient tolerated his treatment without serious acute or long-term side effects. There was no evidence of disease on comprehensive examination or on positron emission tomography or computed tomography scans at the 4.6-year follow up.Conclusion:Surgery followed by adjuvant radiotherapy provided practical locoregional control with acceptable toxicity. Further detailed case reports are warranted to optimise the management of this rare malignancy.

scholarly journals Salivary Duct Carcinoma in the Parotid Gland; Two Case Reports.

2001 ◽  
Vol 94 (12) ◽  
pp. 1105-1110 ◽  
Author(s):  
Tsuyoshi KITANISHI ◽  
Hiroya KITANO ◽  
Akira SHIBANO ◽  
Michiko YOSHII ◽  
Tomoya NAGATA ◽  
...  
Keyword(s):  
Parotid Gland ◽  
Case Reports ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Duct Carcinoma

scholarly journals Primary Salivary Duct Carcinoma Arising from the Stensen Duct

2016 ◽  
Vol 95 (9) ◽  
pp. E15-E17 ◽  
Author(s):  
Kenji Noda ◽  
Takashi Hirano ◽  
Tomoyo Okamoto ◽  
Masashi Suzuki
Keyword(s):  
Computed Tomography ◽  
Neck Dissection ◽  
Clinical Course ◽  
Additional Treatment ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Histologic Diagnosis ◽  
Duct Carcinoma ◽  
The Right

This report describes a salivary duct carcinoma (SDC) arising from the extraglandular portion of the Stensen duct. The patient was a 56-year-old man who presented with a palpable, elastic, hard mass without tenderness in the right cheek. Computed tomography revealed a tumor of the extraglandular portion of the Stensen duct. Supraomohyoid right neck dissection and total right parotidectomy were performed, and the histologic diagnosis was SDC of the Stensen duct. Postoperatively, the patient received no additional treatment. Neither recurrence nor metastasis was observed during 4 years of follow-up examination. SDC of the Stensen duct is extremely rare. To our knowledge, there is no report that describes primary SDC arising from that location. We also believe this is the first report that describes the clinical course of primary SDC arising from a Stensen duct.

The use of immunohistochemistry in the diagnosis of primary salivary duct carcinoma: three case reports

Pathology ◽  
2008 ◽  
Vol 40 (4) ◽  
pp. 434-437 ◽  
Author(s):  
Tamazin Leecy ◽  
Michael E. Buckland ◽  
Jennifer Turner ◽  
Peter Earls
Keyword(s):  
Case Reports ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Duct Carcinoma

scholarly journals Salivary Duct Carcinoma in the External Auditory Canal Causing Ipsilateral Hearing Loss

Diagnostics ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 1312
Author(s):  
Shih-Lung Chen ◽  
Chi-Ju Yeh ◽  
Kai-Chieh Chan
Keyword(s):  
Hearing Loss ◽  
External Auditory Canal ◽  
Case Reports ◽  
Benign Lesion ◽  
Immunohistochemical Analysis ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Case Presentation ◽  
Subcutaneous Lesion

Background: Salivary duct carcinoma (SDC) is a rare aggressive tumor. Most tumors are not confined to the salivary ducts; rather, they invade the major and minor salivary glands. Only a few case reports on such tumors in other primary sites have appeared. Case presentation: A 40-year-old male complained of right hearing loss (a common condition), but we made an extremely rare diagnosis of an SDC in the external auditory canal (EAC). EAC cancers are frequently misdiagnosed. In our patient, the otoscope revealed a smooth, bulging subcutaneous lesion with a non-epithelial defect suggestive of a benign lesion. However, an SDC of the EAC was confirmed through pathological and immunohistochemical analysis. Conclusions: We suggest detailed evaluation of even smooth EAC subcutaneous lesions to avoid erroneous diagnoses. To the best of our knowledge, this is the first report of SDC in the EAC.

scholarly journals Perineural Spread of Salivary Duct Carcinoma to the Internal Auditory Canal

2014 ◽  
Vol 2014 ◽  
pp. 1-3
Author(s):  
Winfred Kitavi ◽  
Ulrich Hamberger ◽  
Holger Sudhoff
Keyword(s):  
Adjuvant Radiotherapy ◽  
Cerebellopontine Angle ◽  
Recurrent Disease ◽  
Malignant Tumors ◽  
Internal Auditory Canal ◽  
Salivary Duct ◽  
Perineural Spread ◽  
Duct Carcinoma ◽  
Surgical Measures ◽  
Total Parotidectomy

Salivary duct carcinomas (SDCs) are high-grade malignant tumors exhibiting aggressive growth with early regional and distant metastasis. We report a case of SDC in a 63-year-old male with early recurrent disease in the cerebellopontine angle (CPA) after total parotidectomy and adjuvant radiotherapy. The tendency of the tumor to recur or metastasize despite radical surgical measures and radiotherapy continues to pose a therapeutic challenge.

scholarly journals Bone marrow metastases in salivary duct carcinoma of the parotid gland

2018 ◽  
Vol 11 (1) ◽  
pp. bcr-2018-226636
Author(s):  
Ameya Asarkar ◽  
Amol Takalkar ◽  
Manish Dhawan ◽  
Cherie Ann O Nathan
Keyword(s):  
Bone Marrow ◽  
Salivary Gland ◽  
Salivary Duct Carcinoma ◽  
Salivary Gland Cancer ◽  
Bone Marrow Metastasis ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Bone Marrow Metastases ◽  
High Index Of Suspicion ◽  
Total Parotidectomy

Salivary duct carcinoma (SDC) is a rare and extremely aggressive salivary gland cancer. An 81-year-old woman with SDC underwent a total parotidectomy with facial nerve sacrifice and a neck dissection. Following surgery, she was diagnosed with disseminated bone marrow metastases. She underwent chemotherapy and trastuzumab for palliation. We present a case of SDC of the parotid which was diagnosed with disseminated bone marrow metastasis following surgery for the primary. This case also highlights the importance of having a high index of suspicion while evaluating highly aggressive tumours like SDC for any atypical findings during workup.

scholarly journals Salivary Duct Carcinoma; Two Case Reports.

2002 ◽  
Vol 95 (5) ◽  
pp. 493-499
Author(s):  
Tomoko TATEYA ◽  
Hiroyuki KITAMURA ◽  
Shin-ichi TAKAGITA ◽  
Yuka IWAHASHI ◽  
Yasutaka KAWATA ◽  
...  
Keyword(s):  
Case Reports ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Duct Carcinoma

The Importance of Adjuvant Radiotherapy in Treatment of Localised Salivary Duct Carcinoma

2011 ◽  
Vol 23 (3) ◽  
pp. S45-S46 ◽  
Author(s):  
F. McGrane ◽  
R.K. Shrimali ◽  
A.G. Robertson ◽  
C. Paterson ◽  
P.D. Correa
Keyword(s):  
Adjuvant Radiotherapy ◽  
Salivary Duct Carcinoma ◽  
Salivary Duct ◽  
Duct Carcinoma

scholarly journals Long-Term Recurrence-Free Survival After Salivary Duct Carcinoma of the Parotid: A 10-Year Follow-Up Case Report

2020 ◽  
pp. 1-3
Author(s):  
Peer W. Kämmerer ◽  
D. Schneider ◽  
Peer W. Kämmerer
Keyword(s):  
Radiation Therapy ◽  
Facial Nerve ◽  
Salivary Duct Carcinoma ◽  
Adjuvant Radiation ◽  
Salivary Duct ◽  
Duct Carcinoma ◽  
Parotid Region ◽  
Parotid Neoplasm ◽  
The Right

Salivary duct carcinoma (SDC) represents a very rare and aggressive parotid neoplasm. A 70-year-old male was admitted to the hospital with a swelling of the right parotid region, persisting for twelve weeks. Based on sonography and contrast-enhanced computed tomography, a suspicious lesion showing mass expansion and invasion of surrounding tissues was seen. Intraoperative biopsy brought evidence of SDC. In accordance, surgical treatment included parotidectomy with preservation of the facial nerve as well as ipsilateral neck dissection due to suspicious lymphatic nodes. Afterwards, an adjuvant radiation therapy was undertaken. At 10 years of follow-up, the patient was alive and free of recurrence with full function of the facial nerve. In conclusion, keeping in mind its poor prognosis, the rare parotid salivary duct carcinoma needs aggressive therapy consisting of a surgical as well as a radiation therapy approach.

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