scholarly journals Observation of Clinical Efficacy of Parylene-Coated Occluder Based on Electronic Image of Visual Sensor in the Treatment of Congenital Heart Disease

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Hongdu Fu ◽  
Liming Liang ◽  
Huangwei Zhuang ◽  
Jiahui Yang
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Clinical Efficacy ◽  
Congenital Heart ◽  
Left Ventricular ◽  
System Level ◽  
Left Ventricular Cavity ◽  
Two Dimensional ◽  
Target Structure ◽  
Visual Sensor

With the acceleration of people’s life rhythm, the incidence of congenital heart disease is getting higher and higher. This study mainly explores the clinical efficacy observation of parylene-coated occluders based on the electronic image of the visual sensor in the treatment of congenital heart disease. The patient takes a supine position and observes whether the target structure (left ventricular cavity) information is separated from the capture area during rotation, and the angle of the probe is adjusted to ensure that as much target structure information as possible can be obtained during the two-dimensional image acquisition. During the three-dimensional ultrasound sampling process, a total of 60 coaxial images were collected within the range of 180°. To reflect the effect of virtual reality, it is necessary to provide users with interactive operation tools. This research provides two methods, mouse interaction and keyboard interaction. Through these two methods, the effect of the basic virtual endoscope is realized. Xtion’s image registration process is completed inside its PS1080 system-level chip, and all sensor information, color images, and depth images are transmitted to the user host through the USB interface. For example, the point of view can be placed in the heart, because the simulation occlusion must first find a suitable section to better observe and judge the occlusion effect. Therefore, this study uses the mouse interaction method to change the cutting by dragging and rotating the mouse. In the process of releasing the occluder, the parylene-coated occluder can be released after the X-ray and ultrasound examination results are satisfactory, and the delivery long sheath and catheter can be sprinkled and compressed to stop the bleeding. During the operation, the ASD measured by two-dimensional ultrasound after balloon inflation was 24.17 ± 7.94  mm, and the anterior and posterior diameter was 21.30 ± 6.54  mm. This research is helpful for the qualitative and quantitative diagnosis of congenital heart disease.

scholarly journals Prognostic Value of CTA-Derived Left Ventricular Mass in Neonates with Congenital Heart Disease

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1215
Author(s):  
Stephan Ellmann ◽  
Julie-Marie Nickel ◽  
Rafael Heiss ◽  
Nouhayla El Amrani ◽  
Wolfgang Wüst ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Left Ventricular Mass ◽  
Congenital Heart ◽  
Left Ventricular ◽  
Surgical Approaches ◽  
Pulmonary Artery Stenosis ◽  
Operating Characteristics ◽  
Ventricular Mass ◽  
Therapeutic Decisions

For therapeutic decisions regarding uni- or biventricular surgical repair in congenital heart disease (CHD), left ventricular mass (LVM) is an important factor. The aim of this retrospective study was to determine the LVM of infants with CHD in thoracic computed tomography angiographies (CTAs) and to evaluate its usefulness as a prognostic parameter, with special attention paid to hypoplastic left heart (HLH) patients. Manual segmentation of the left ventricular endo- and epicardial volumes was performed in CTAs of 132 infants. LVMs were determined from these volumes and normalized to body surface area. LVMs of patients with different types of CHD were compared to each other using analyses of variances (ANOVA). An LVM cutoff for discrimination between uni- and biventricular repair was determined using receiver operating characteristics. Survival rates were calculated using Kaplan–Meier statistics. Patients with a clinical diagnosis of an HLH had significantly lower mean LVM (21.88 g/m2) compared to patients without applicable disease (50.22 g/m2; p < 0.0001) and compared to other CHDs, including persistent truncus arteriosus, left ventricular outflow tract obstruction, transposition of the great arteries, pulmonary artery stenosis or atresia, and double-outlet right ventricle (all, p < 0.05). The LVM cutoff for uni- vs. biventricular surgery was 33.9 g/m2 (sensitivity: 82.3%; specificity: 73.7%; PPV: 94.9%). In a subanalysis of HLH patients, a sensitivity of 50.0%, specificity of 100%, PPV of 100%, and NPV of 83.3% was determined. Patient survival was not significantly different between the surgical approaches or between patients with LVM above or below the cutoff. LVM can be measured in chest CTA of newborns with CHD and can be used as a prognostic factor.

Abstract 14771: Obstructive Sleep Apnea is Associated With Cardiac Dysfunction in Children With Congenital Heart Disease

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Daniel Combs ◽  
Vanessa Fernandez ◽  
brent j barber ◽  
Wayne J Morgan ◽  
Chiu-Hsieh Hsu ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Obstructive Sleep Apnea ◽  
Heart Disease ◽  
Sleep Apnea ◽  
Right Ventricular ◽  
Cardiac Dysfunction ◽  
Congenital Heart ◽  
Left Ventricular ◽  
Sleep Study ◽  
Obstructive Sleep

Introduction: Obstructive sleep apnea (OSA) is associated with cardiac dysfunction in children without congenital heart disease (CHD). Children with CHD are at increased risk for OSA and may be susceptible to further cardiovascular consequences due to OSA but the extent and nature of such cardiovascular effects of OSA are unknown. Methods: Children (6-17 years old) with corrected CHD without current cyanosis or Down syndrome were recruited from pediatric cardiology clinic. Home sleep tests were done to determine the presence and severity of OSA. OSA was defined as an obstructive apnea hypopnea index (oAHI) ≥1. Mild OSA was defined as an oAHI of ≥1 to <5 and moderate OSA was defined as an oAHI of ≥5 to <10. Standard clinically indicated echocardiograms were performed in clinic. Echocardiographic findings were compared between children with CHD with and without comorbid OSA using t-tests, Wilcoxon-sign rank tests as well as linear or logistic regression as appropriate. Results: Thirty-two children had sleep study and echocardiographic data available. OSA was present in 18 children (56%). OSA was mild in 89% and moderate in 11% of cases. There were no significant differences in age, body mass index, CHD severity, gender or ethnicity between children with and without OSA. Children with OSA had larger height-indexed right ventricular end-diastolic diameter (RVDi) compared to those without OSA (median 1.35, 95% CI 1.09, 1.56 vs. 1.21, 95% CI 1.01, 1.57; p=0.04). Children with moderate OSA had a reduced left ventricular shortening fraction compared to both those with mild OSA and no OSA (30.0 ± 6.1% vs. 38.7 ± 4.4%; p=0.009 and 39.2 ± 3.6%; p=0.007, respectively). Children with moderate OSA had increased left ventricular end-systolic diameter compared to those with mild OSA and no OSA (3.4 ± 0.4 cm vs. 2.5 ± 0.4; p=0.007 and 2.4 ± 0.5; p=0.001, respectively). Children with an RVDi above the median were seven times more likely to have OSA than those with an RVDi below the median (odds ratio 6.9.; 95% CI 1.3, 35; p=0.02). Conclusions: OSA is associated with changes in cardiac morphology and reduced contractility in children with CHD. Additionally, the presence of right ventricular dilation may suggest the need for OSA evaluation in children with CHD.

scholarly journals Left Ventricular Pressure-Volume Characteristics in Congenital Heart Disease

Circulation ◽  
1968 ◽  
Vol 37 (6) ◽  
pp. 879-889 ◽  
Author(s):  
M. M. JARMAKANI ◽  
SAM B. EDWARDS ◽  
MADISON S. SPACH ◽  
RAMON V. CANENT ◽  
M. PAUL CAPP ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Congenital Heart ◽  
Left Ventricular Pressure ◽  
Left Ventricular ◽  
Ventricular Pressure ◽  
Volume Characteristics

An adult female with 5q34-q35.2 deletion: A rare syndromic presentation of left ventricular non-compaction and congenital heart disease

2020 ◽  
Vol 63 (4) ◽  
pp. 103797
Author(s):  
Priyanka Arya ◽  
Theodore E. Wilson ◽  
John J. Parent ◽  
Stephanie M. Ware ◽  
Amy M. Breman ◽  
...  
Keyword(s):  
Congenital Heart Disease ◽  
Heart Disease ◽  
Adult Female ◽  
Congenital Heart ◽  
Left Ventricular
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