Outcomes of a Foldable Capsular Vitreous Body Implantation: A Retrospective Study

Background. The vitreous body is an important part of the ocular body fluid. A foldable capsular vitreous body (FCVB) is designed to treat chronic adverse complications in severe ocular trauma and silicone oil-dependent eyes. This study is aimed at investigating a method for implanting an FCVB, its postoperative efficacy, and clinical value. Methods. A retrospective analysis was performed on data from 18 patients who underwent vitrectomy and FCVB implantation for severe ocular trauma and silicone oil-dependent eyes between March 2019 and May 2020. All treated eyes underwent clinical examinations involving the best-corrected visual acuity, intraocular pressure, FCVB position, anterior segment photography, and wide-angle fundus photography regularly after surgery. Results. Eighteen eyes from 18 patients were enrolled in this study. A total of 2.00–4.20 ( 3.46 ± 0.78 ) ml of silicone oil were injected into the FCVB during surgery. The patients were followed up at 1, 2, and 4 weeks and 3, 6, and 12 months after surgery. Twelve months after surgery, visual acuity improved in 7 (38.89%) eyes. In contrast, 10 (55.56%) eyes showed no obvious improvement, and 1 (5.56%) eye had decreased vision. Intraocular pressure at 12 months was 10.13 ± 3.52 mmHg, which was comparable to that before the surgery ( t = 0.38 , P = 0.71 ). The anterior chamber depth examined by slit lamp was 2.00–3.00 cornea thickness (CT) in 7 eyes, 1.00–2.00 CT in 2 eyes, and <1.00 CT in one eye. The anterior chamber disappeared in eight eyes. There were eight eyes with clear cornea, four eyes with localized opacity, and two eyes with obvious gray-white opacity. There was no case of severe FCVB deflection, rupture, or exposure during the observation period. Conclusion. FCVB implantation is an effective and safe treatment for eyes with severe ocular trauma and silicone oil-dependent eyes. It may support retinal reattachment, slow down eyeball atrophy, reduce the risk of chronic adverse complications such as corneal endothelial decompensation, and maintain intraocular pressure and preoperative visual function.

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Clinical Application of Foldable Capsular Vitreous Bodies in the Treatment of Severe Ocular Trauma and Silicone Oil Dependent Eyes

10.21203/rs.3.rs-751052/v1 ◽

2021 ◽

Author(s):

Hao Jiang ◽

Chao Xue ◽

Yanlin Gao ◽

Ying Chen ◽

Yan Wang

Keyword(s):

Visual Acuity ◽

Clinical Application ◽

Ocular Trauma ◽

Silicone Oil ◽

Anterior Segment ◽

Vitreous Body ◽

Corneal Opacity ◽

Ultrasound Biomicroscopy ◽

Significant Difference

Abstract Background: Recently, a new type of foldable capsular vitreous body (FCVB) has been developed for clinical application to fill the vitreous cavity with vitreous substitutes. It may be an ideal substitute for the vitreous body in eyes with severe retinal detachment. The aim of this study was to assess the application of a foldable capsular vitreous body (FCVB) in the treatment of severe ocular trauma and silicone oil (SO) dependent eyes.Methods: A retrospective analysis was performed on the clinical application of FCVB in the treatment of severe ocular trauma and SO dependent eyes. The results of best-corrected visual acuity and intraocular pressure (IOP) evaluation, B-scan ultrasonography or color Doppler ultrasonography, ultrasound biomicroscopy, and anterior segment photography were recorded during follow-up. A paired t-test was used to compare the difference in IOP before and after FCVB implantation. Results: Seven eyes of seven patients were included in the 6 months follow-up. In all cases, B-scan ultrasonography and ultrasound biomicroscopy showed that FCVB adapted closely to the globe wall and ciliary body, thus supporting the retina. Visual acuity did not improve, except in one case from LP to HM. The mean±SD IOP was 9.29±1.60mmHg prior to FCVB implantation and 10.43±0.98mmHg after implantation, with no significant difference between these measurements (P=0.066). Five of the seven patients developed differing degrees of corneal opacity and keratopathy. Conclusions: FCVB implantation may be a safe and effective method for the treatment of severe ocular trauma and SO dependent eyes. However, corneal opacity and keratopathy are potential serious complications after surgery. Appropriate case selection and proper surgical time require further investigation.

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Anatomical and Visual Effects of Implantable Phakic Contact Lens on Correction of Myopia

10.21203/rs.3.rs-1245764/v1 ◽

2022 ◽

Author(s):

Mahmoud Ekram ◽

Ahmed Mohamed Kamal Elshafei ◽

Asmaa Anwar Mohamed ◽

Mohamed Farouk Sayed Othman Abdelkader

Keyword(s):

Visual Acuity ◽

Anterior Chamber ◽

Contact Lens ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Case Series ◽

Care Group ◽

Case Series Study ◽

Significant Difference ◽

The Mean

Abstract Purpose: To evaluate the anatomical effects of implantable phakic contact lens (IPCL) (Care Group, India) on anterior segment and its visual outcomes .Patients and methods: In a prospective interventional case series study, 60 highly myopic eyes of 32 patients were subjected to IPCL implantation in the Ophthalmology Department of Minia University Hospital, Egypt from January 2019 to June 2021. All patients had complete ophthalmic examination and were followed up for 1 year. Pentacam was used for preoperative and postoperative estimation of anterior chamber depth (ACD), anterior chamber angle (ACA), anterior chamber volume (ACV) and IPCL vault in the 1st, 3rd, and 12th months. Assessment of corneal endothelium was done using specular microscope preoperatively and after 12 months. Preoperative and postoperative refraction and visual acuity were measured. Results: There was a statistically significant decrease in ACD, ACA, and ACV. There was no significant difference between preoperative and postoperative mean intraocular pressure (IOP) by the 12th month (P=0.163). The mean preoperative endothelial cell count (ECD) was significantly reduced from 2929.3±248 cells/mm2 to 2737.9±303 cells/mm2 at the 12th month (P<0.001). with a statistically highly significant improvement of mean Log Mar uncorrected visual acuity (UCVA) from 1.48±0.19 preoperatively to 0.46±0.11 by the end of follow up (P<0.001) with insignificant difference between preoperative best corrected visual acuity (BCVA) and postoperative UCVA (P=0.209). In the 12th month, the mean vault was 240±540 μm. No sight threatening complications occurred.Conclusion: Although IPCL induced anatomical changes, it was safe and effective for correction of high myopia.

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Single-pass four-throw pupilloplasty for secondary angle-closure glaucoma associated with silicon oil tamponade

European Journal of Ophthalmology ◽

10.1177/1120672118780809 ◽

2018 ◽

Vol 29 (5) ◽

pp. 561-565 ◽

Cited By ~ 1

Author(s):

Priya Narang ◽

Ashar Agarwal ◽

Amar Agarwal

Keyword(s):

Optical Coherence Tomography ◽

Visual Acuity ◽

Intraocular Pressure ◽

Anterior Chamber ◽

Anterior Segment ◽

Angle Closure Glaucoma ◽

Angle Closure ◽

Single Pass ◽

Silicon Oil ◽

The Mean

Purpose: To describe the feasibility and efficacy of performing single-pass four-throw pupilloplasty for secondary angle-closure glaucoma post silicon oil tamponade. Methods: The procedure was performed in five eyes of five patients. All the cases underwent silicon oil removal with single-pass four-throw pupilloplasty. Single-pass four-throw procedure involves a single pass of needle through the iris tissue that is to be apposed followed by taking four throws by passing the suture end through the loop that is withdrawn from the anterior chamber as in a modified Siepser’s slip-knot technique. Both the suture ends are pulled and this leads to sliding of the loop into the anterior chamber. Surgical pupilloplasty stretches the peripheral iris tissue and helps in breaking the peripheral anterior synechia. Intraoperative gonioscopy and anterior segment optical coherence tomography were performed in all the cases. Results: Intraoperative gonioscopy and anterior segment optical coherence tomography demonstrated opening of the anterior chamber angles with breakage of peripheral anterior synechia. The mean preoperative and postoperative best-corrected visual acuity in logarithm of minimum angle of resolution was 1.24 ± 0.23 and 0.56 ± 0.18, respectively (p < 0.001). The mean preoperative and postoperative intraocular pressure was 38.2 ± 4.97 and 13.0 ± 2.35 mm Hg, respectively. There was a significant decrease in intraocular pressure and marked improvement in visual acuity in all the cases. Conclusion: Surgical pupilloplasty helps to relieve the post-silicon oil-induced secondary angle-closure glaucoma by breaking peripheral anterior synechia and significantly opening the anterior chamber angles.

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Evaluation the Acute Effects of Hyperbaric Oxygen Therapy on Eye Anterior Segment Morphology and on İntraocular Pressure

10.21203/rs.3.rs-528769/v1 ◽

2021 ◽

Author(s):

Fatih Akıncı ◽

Abdullah Arslan ◽

Muammer Özcimen

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Hyperbaric Oxygen ◽

Hyperbaric Oxygen Therapy ◽

Central Corneal Thickness ◽

Oxygen Therapy ◽

Corneal Thickness ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Iridocorneal Angle

Abstract Purpose: In this study the acute effects of 1 session of hyperbaric oxygen therapy on eye anterior segment morphology and on intraocular pressure was evaluated.Materials and methods: 30 patients taking hyperbaric oxygen therapy for different indications were included in this prospective study. Only the right eye per patient was included in the study. The refractive errors were measured with autorefractometry, intraocular pressures were measured with pneumatic tonometry; anterior segment parameters pachymetry, keratometry, anterior chamber depth and iridocorneal angle values were measured with corneal topography prior to and 24 hours after 1 session of hyperbaric oxygen therapy.Results: In this study 30 eyes from a total of 30 patients were evaluated; 19 men (% 64) and 11 women (% 36). Median age was 44.33 ±16.12 (Age range 18-80 years). Mean intraocular pressure was 13.7 ±4,16 mmHg (milimetermercuries), mean central corneal thickness was 531.9 ±28.24 μm, mean anterior chamber depth was 3.30 ±0.375 mm, mean iridocorneal angle value was 35.3± 6.61 degrees before hyperbaric oxygen therapy. The mean intraocular pressure was 12.66±4,54 mmHg, mean central corneal thickness was 529.43± 26.68 μm, mean anterior chamber depth was 3.28±0.372 mm, mean iridocorneal angle value was 34.5±6.42 degrees after HBOT. A statistically significant decrease in these values were recorded. No statistically significant changes were found in spheric equivalent and keratometry values of the patients before and after HBOT.Conclusions: After one session of HBOT a decrease in intraocular pressure, central corneal thickness, anterior chamber depth and iridocorneal angles of patients were observed; keratometry and spheric equivalent values remained unchanged. More studies are needed in order to use the effects of HBOT on anterior segment morphology and on intraocular pressure for situations like glaucoma, corneal edema etc.

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The changes of anatomic and topographic characteristics of eye anterior segment after uncomplicated cataract phacoemulsification

Kazan medical journal ◽

10.17816/kmj1805 ◽

2013 ◽

Vol 94 (6) ◽

pp. 853-858

Author(s):

A A Ryabtseva ◽

M P Yugaj ◽

N S Nikitina

Keyword(s):

Intraocular Pressure ◽

Anterior Chamber ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Ultrasound Biomicroscopy ◽

Anterior Chamber Angle ◽

Ciliary Processes ◽

Lens Implantation ◽

Topographic Characteristics ◽

Chamber Angle

Aim. To study the changes of anatomic and topographic characteristics of the eye anterior segment after uncomplicated cataract phacoemulsification using corneal incision with intraocular soft lens implantation. Methods. The data of ultrasound biomicroscopy and noncontact tonometry of 58 eyes (56 patients, 32 females, 24 males aged 54 to 78 years) before and after cataract phacoemulsification were analyzed. Paitents with survived ocular trauma, refractive keratoplasty, glaucoma, uveitis, and surgical complications (incomplete capsulorrhexis, posterior capsule rupture, ciliary zonule disinsertion, corneal burn). Apart from the common examinations (visual acuity testing, tonometry, tonography, eye A- and B-ultrasonography, biomicroscopy), all patients underwent eye ultrasound biomicroscopy. Results. Anterior chamber depth increased from 2.73±0.10 to 4.17±0.06 mm (p ≤0.001). Trabecula-iris distance measured at 500 μm from the scleral spur, increased from 0.38±0.02 to 0.47±0.02 mm (p ≤0.001). Anterior chamber angle increased from 28.69±1.87 to 42.73±1.56 degrees (p ≤0.001), the angle between the iris and the sclera increased from 32.78±1.39 to 41.36±0.84 degrees (p ≤0.001), the angle between the sclera and ciliary processes increased from 39.48±1.29 to 45.30±1.16 degrees (p ≤0.001). Intraocular pressure according to the non-contact tonometry data decreased from 18.16±1.29 to 13.55±0.95 mm Hg (p ≤0.001). Conclusion. Anterior chamber depth, trabecula-iris distance, anterior chamber angle, the angle between sclera and iris and the angle between sclera and ciliary processes increased significantly after phacoemulsification with intraocular lens implantation. Intraocular pressure decreased significantly according to the non-contact tonometry data.

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Assessment of Anterior Segment Changes in Pseudophakic Eyes, Using Ultrasonic Biomicroscopic Imaging, after Pars Plana Vitrectomy with Silicone Oil or Gas Tamponade

Journal of Ophthalmology ◽

10.1155/2016/8303792 ◽

2016 ◽

Vol 2016 ◽

pp. 1-8 ◽

Cited By ~ 1

Author(s):

Erkan Ünsal ◽

Kadir Eltutar ◽

Belma Karini ◽

Osman Kızılay

Keyword(s):

Intraocular Pressure ◽

Pars Plana Vitrectomy ◽

Silicone Oil ◽

Morphological Changes ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Ciliary Process ◽

Pars Plana ◽

Group 2 ◽

Group 1

Objective. To evaluate the morphological changes of the anterior segment using ultrasonic biomicroscopy (UBM) imaging in pseudophakic patients who underwent pars plana vitrectomy (PPV) with silicone oil or gas (C3F8) internal tamponade agent injection.Method. This prospective study included pseudophakic patients with planned PPV, divided into two groups according to internal tamponade agent: those in which silicone oil was used (n=27, Group 1) and those in which gas (C3F8) was used (n=24, Group 2). UBM measurements were performed in the supine position before and one week after surgery.Results. In patients of Group 1, postoperative trabecular meshwork-ciliary process distance (T-CPD) and iris-ciliary process distance (I-CPD), according to preoperative values, were found to be statistically significantly reduced, and postoperative mean value of scleral thickness (ST) and intraocular pressure (IOP), according to preoperative value, was found to be statistically significantly increased. In patients of Group 2, postoperative mean values of anterior chamber depth (ACD), ciliary body thickness (CBT), T-CPD, I-CPD, and IOP, according to preoperative values, were found to be statistically significantly reduced. Preoperatively, in Group 2 patients, according to Group 1 patients, TIA and IOP were found to be statistically significantly increased. Preoperative and postoperative IOP between the measured parameters with UBM showed no statistically significant correlation.Conclusions. Gases cause more morphological changes in the anterior segment structures. It is thought that complications such as increased intraocular pressure can be seen more frequently for this reason.

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Trabeculectomy in Staphyloma Eye with High Intraocular Pressure Following Ocular Trauma – A Case Report

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.6313 ◽

2021 ◽

Vol 9 (T3) ◽

pp. 23-25

Author(s):

Masitha Dewi Sari

Keyword(s):

Intraocular Pressure ◽

Case Report ◽

Anterior Chamber ◽

Ocular Trauma ◽

Anterior Segment ◽

Rectus Muscle ◽

Tissue Destruction ◽

Corneal Scar ◽

History Of ◽

Blurry Vision

BACKGROUND: Ocular trauma may alter the anterior segment condition that may lead to secondary glaucomas such as inflammation, hyphema, angle recession, and lens subluxation. One of the most common procedures to decrease intraocular pressure (IOP) is trabeculectomy by creating pathways that allow aqueous humor to flow out of the anterior chamber. Scleral tissue destruction can cause damage in thin areas (such as posterior to the rectus muscle insertions) as in case of scleritis. CASE REPORT: An 11-year-old boy presented to the Ophthalmology Department of Universitas Sumatera Utara Hospital with a bigger white grayish mass and blurry vision. There was a history of the left ocular trauma 6 years ago, followed by redness of the eye, but not treated properly. On the general examination, the patient’s left eyes looked cloudy. On ocular examination, the left eye visual acuity was 1/300 and IOP was 28 mmHg. Segment anterior examination showed staphyloma from 9 to 12 o’clock, conjunctival injection, corneal scar, shallow anterior chamber, and cloudy lens. We could not asses the posterior segment due to cloudy media. We gave anti-glaucoma medication for 1 month, but the IOP did not decrease. We performed a trabeculectomy to control IOP and to prevent staphyloma from getting bigger. CONCLUSION: Trabeculectomy was an effective procedure to control IOP in a staphyloma eye following ocular trauma.

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Study On the Effectiveness and Safety of FCVB Implantation

10.21203/rs.2.233/v1 ◽

2019 ◽

Author(s):

Xiangyang Zhang ◽

Xuemin Tian ◽

Baike Zhang ◽

Lisa Guo ◽

Xiaodan Li ◽

...

Keyword(s):

Visual Acuity ◽

Intraocular Pressure ◽

Vitreous Body ◽

Vitreous Cavity ◽

Fundus Photography ◽

Vitreoretinal Disease ◽

Applanation Tonometer ◽

Retinal Reattachment ◽

Vitreoretinal Diseases ◽

The Difference

Abstract Background: To investigate the efficacy and safety of the foldable capsular vitreous body(FCVB) in the treatment of vitreoretinal diseases. Methods: A retrospective analysis was conducted involving 20 patients (20 eyes) who underwent FCVB implantation in our hospital from September 2017 to April 2018. All the patients underwent vitrectomyand FCVB implantation, a standard three-port vitrectomy was performed, and the FCVB was implanted into the vitreous cavity. At 6 months after surgery, the visual acuity chart, Goldmann applanation tonometer, fundus photography, B-ultrasound examination, and optical coherence tomography (OCT) examination were performed on the treated eyes.The patients’ vision, intraocular pressure, retinal reattachment, and FCVB status were observed. Results: Compared with the preoperative measurements, there was no change in visual acuity in 18 eyes at 6 months after FCVB implantation, and the difference was not significant (P=1.000); the intraocular pressure of these 18 eyes returned to normal, and the difference was significant (P=0.00001); in fundus photographyimages of these 18 eyes, B-ultrasound,OCT showed good retinal reattachment, FCVB distributed well in the vitreous cavity and evenly supported the vitreous retina and there was no obvious abnormality. The eyes were symmetrical, and the eyeball activity was normal. One patient developed eyeball atrophy after surgery, and one patient developed ocular inflammation after surgery. The condition improved after treatment. Conclusions: FCVB is an effective and safe vitreous substitute during the 6-month implantation period and is able to maintain eye shape, intraocular pressure and good aesthetics. Keywords: Vitreoretinal disease; vitrectomy; FCVB; intraocular pressure.

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Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation

BMC Ophthalmology ◽

10.1186/s12886-019-1268-x ◽

2019 ◽

Vol 19 (1) ◽

Cited By ~ 3

Author(s):

Xiangyang Zhang ◽

Xuemin Tian ◽

Baike Zhang ◽

Lisa Guo ◽

Xiaodan Li ◽

...

Keyword(s):

Retinal Detachment ◽

Ocular Trauma ◽

Silicone Oil ◽

Vitreous Body ◽

Fundus Photography ◽

Specular Microscopy ◽

Applanation Tonometer ◽

Before And After ◽

Fellow Eyes

Abstract Background Foldable capsular vitreous body (FCVB) was designed to treat severe retinal detachment. The aim of this study was to evaluate the efficacy and safety of the implantation of foldable capsular vitreous body in 1-year follow-up. Methods A retrospective analysis was conducted for 20 patients with severe ocular trauma or silicone oil (SO) dependent eyes underwent vitrectomy and FCVB implantation in a 1-year follow-up. All treated eyes were peformed clinical examinations involved the visual acuity (VA) examination, Goldmann applanation tonometer, noncontact specular microscopy, fundus photography, B-Scan examination and optical coherence tomography (OCT). The groups were compared with t-test and the McNemar - Bowker test. Results In 1-year follow-up, 20 eyes were evaluated in the study. FCVB well supported the vitreous retina in all treated eyes, and 6 treated eyes achieved retinal reattachment 12 months after FCVB implantation. There were no significant differences in VA before and after FCVB implantation (P = 1.000). In addition, the postoperative IOP markedly elevated from the preoperative IOP of 12.90 ± 7.06 mmHg to 15.15 ± 3.36 mmHg (P = 0.000017). The intraocular pressure (IOP) of 10 eyes maintained at a normal level after surgeries. The other 10 eyes showed slightly lower IOP within the acceptable level. Though two patients developed keratopathy and ocular inflammation respectively, other treated eyes were symmetric with fellow eyes showing satisfactory appearance. Moreover, there was no SO emulsification or leakage happened in the observation. Conclusions FCVB implantation was an effective and safe treatment in the eyes with severe retinal detachment.

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Ocular biometric changes after trabeculectomy

Srpski arhiv za celokupno lekarstvo ◽

10.2298/sarh171218060r ◽

2019 ◽

Vol 147 (5-6) ◽

pp. 341-347

Author(s):

Marija Radenkovic ◽

Gordana Stankovic-Babic ◽

Jasmina Djordjevic-Jocic ◽

Maja Zivkovic ◽

Marija Trenkic-Bozinovic ◽

...

Keyword(s):

Visual Acuity ◽

Anterior Chamber ◽

Axial Length ◽

Spontaneous Recovery ◽

Open Angle Glaucoma ◽

Anterior Segment ◽

Anterior Chamber Depth ◽

Glaucoma Surgery ◽

Biometric Analysis ◽

The Difference

Introduction/Objective. Trabeculectomy is a conventional filtration procedure in surgical glaucoma treatment. Even after successful trabeculectomy, the patient?s visual acuity can be reduced. Studies (1991) showed that changes in visual acuity occur due to changes of corneal curvature and anterior chamber depth. Anterior chamber depth change for 1 mm results in about 2 diopters change in refractive sphere. Simultaneous with anterior segment changes, anti-glaucoma surgery effect can also be manifested in posterior segment of the eye: choroidal thickness, axial length and the ocular perfusion. Axial length reduction after trabeculectomy was supposed according to biometry, more pronounced if intraocular pressure is higher preoperatively, or in the first postoperative week with spontaneous recovery to preoperative values one year after surgery. A study was conducted at the Clinic for Eye Diseases in Nis to determine the difference in pre/post-operative values of biometry on 60 patients with glaucoma. Methods. In this study we used retrospective-prospective biometric analysis in patients with open-angle glaucoma. Results. Anterior chamber depth was significantly different during the observed period, for 1.1 mm in first week (p < 0.0001) in the whole group and glaucoma type. The mean axial length varies considerably during the observed period, shorter for 0.39 mm in first week (p < 0.05). Conclusion. By analyzing biometric parameters, a postoperative difference of biometry with spontaneous recovery was determined. There is a difference in postoperative visual acuity of patients compared to preoperative, with spontaneous recovery at the end of the follow-up.

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