scholarly journals Study On the Effectiveness and Safety of FCVB Implantation

2019 ◽  
Author(s):  
Xiangyang Zhang ◽  
Xuemin Tian ◽  
Baike Zhang ◽  
Lisa Guo ◽  
Xiaodan Li ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Vitreous Body ◽  
Vitreous Cavity ◽  
Fundus Photography ◽  
Vitreoretinal Disease ◽  
Applanation Tonometer ◽  
Retinal Reattachment ◽  
Vitreoretinal Diseases ◽  
The Difference

Abstract Background: To investigate the efficacy and safety of the foldable capsular vitreous body(FCVB) in the treatment of vitreoretinal diseases. Methods: A retrospective analysis was conducted involving 20 patients (20 eyes) who underwent FCVB implantation in our hospital from September 2017 to April 2018. All the patients underwent vitrectomyand FCVB implantation, a standard three-port vitrectomy was performed, and the FCVB was implanted into the vitreous cavity. At 6 months after surgery, the visual acuity chart, Goldmann applanation tonometer, fundus photography, B-ultrasound examination, and optical coherence tomography (OCT) examination were performed on the treated eyes.The patients’ vision, intraocular pressure, retinal reattachment, and FCVB status were observed. Results: Compared with the preoperative measurements, there was no change in visual acuity in 18 eyes at 6 months after FCVB implantation, and the difference was not significant (P=1.000); the intraocular pressure of these 18 eyes returned to normal, and the difference was significant (P=0.00001); in fundus photographyimages of these 18 eyes, B-ultrasound,OCT showed good retinal reattachment, FCVB distributed well in the vitreous cavity and evenly supported the vitreous retina and there was no obvious abnormality. The eyes were symmetrical, and the eyeball activity was normal. One patient developed eyeball atrophy after surgery, and one patient developed ocular inflammation after surgery. The condition improved after treatment. Conclusions: FCVB is an effective and safe vitreous substitute during the 6-month implantation period and is able to maintain eye shape, intraocular pressure and good aesthetics. Keywords: Vitreoretinal disease; vitrectomy; FCVB; intraocular pressure.

scholarly journals Study On the Effectiveness and Safety of Foldable Capsular Vitreous Body Implantation

2019 ◽  
Author(s):  
Xiangyang Zhang ◽  
Xuemin Tian ◽  
Baike Zhang ◽  
Lisa Guo ◽  
Xiaodan Li ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Vitreous Body ◽  
Vitreous Cavity ◽  
Fundus Photography ◽  
Applanation Tonometer ◽  
Retinal Reattachment ◽  
Vitreoretinal Diseases ◽  
The Difference ◽  
Implantation Period

Abstract Background: To investigate theefficacy and safety of the foldable capsular vitreous body(FCVB) in the treatment of vitreoretinal diseases. Methods: A retrospective analysis was conducted involving 20 patients (20 eyes) who underwent FCVB implantation in our hospital from September 2017 to April 2018. All the patients underwent vitrectomyand FCVB implantation, a standard three-port vitrectomy was performed, and the FCVB was implanted into the vitreous cavity. At 6 months after surgery, the visual acuity chart, Goldmann applanation tonometer, fundus photography, B-ultrasound examination, and optical coherence tomography (OCT) examination were performed on the treated eyes.The patients’ vision, intraocular pressure, retinal reattachment, and FCVB status were observed. Results: Compared with the preoperative measurements, there was no change in visual acuity in 18 eyes at 6 months after FCVB implantation, and the difference was not significant (P=1.000); the intraocular pressure of these 18 eyes returned to normal, and the difference was significant (P=0.00001); in fundus photographyimages of these 18 eyes, B-ultrasound,OCT showed good retinal reattachment, FCVB distributed well in the vitreous cavity and evenly supported the vitreous retina and there was no obvious abnormality. The eyes were symmetrical, and the eyeball activity was normal. One patient developed eyeball atrophy after surgery, and one patient developed ocular inflammation after surgery. The condition improved after treatment. Conclusions: FCVB is an effective and safe vitreous substitute during the 6-month implantation period and is able to maintain eye shape, intraocular pressure and good aesthetics.

scholarly journals Outcomes of a Foldable Capsular Vitreous Body Implantation: A Retrospective Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Xiangzhong Xu ◽  
Huimin Ge ◽  
Jiajun Li ◽  
Weihong Shang ◽  
Yuke Ji ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Anterior Chamber ◽  
Ocular Trauma ◽  
Silicone Oil ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Vitreous Body ◽  
Fundus Photography ◽  
Clinical Value

Background. The vitreous body is an important part of the ocular body fluid. A foldable capsular vitreous body (FCVB) is designed to treat chronic adverse complications in severe ocular trauma and silicone oil-dependent eyes. This study is aimed at investigating a method for implanting an FCVB, its postoperative efficacy, and clinical value. Methods. A retrospective analysis was performed on data from 18 patients who underwent vitrectomy and FCVB implantation for severe ocular trauma and silicone oil-dependent eyes between March 2019 and May 2020. All treated eyes underwent clinical examinations involving the best-corrected visual acuity, intraocular pressure, FCVB position, anterior segment photography, and wide-angle fundus photography regularly after surgery. Results. Eighteen eyes from 18 patients were enrolled in this study. A total of 2.00–4.20 ( 3.46 ± 0.78 ) ml of silicone oil were injected into the FCVB during surgery. The patients were followed up at 1, 2, and 4 weeks and 3, 6, and 12 months after surgery. Twelve months after surgery, visual acuity improved in 7 (38.89%) eyes. In contrast, 10 (55.56%) eyes showed no obvious improvement, and 1 (5.56%) eye had decreased vision. Intraocular pressure at 12 months was 10.13 ± 3.52  mmHg, which was comparable to that before the surgery ( t = 0.38 , P = 0.71 ). The anterior chamber depth examined by slit lamp was 2.00–3.00 cornea thickness (CT) in 7 eyes, 1.00–2.00 CT in 2 eyes, and <1.00 CT in one eye. The anterior chamber disappeared in eight eyes. There were eight eyes with clear cornea, four eyes with localized opacity, and two eyes with obvious gray-white opacity. There was no case of severe FCVB deflection, rupture, or exposure during the observation period. Conclusion. FCVB implantation is an effective and safe treatment for eyes with severe ocular trauma and silicone oil-dependent eyes. It may support retinal reattachment, slow down eyeball atrophy, reduce the risk of chronic adverse complications such as corneal endothelial decompensation, and maintain intraocular pressure and preoperative visual function.

scholarly journals Nd:YAG Laser Vitreolysis for Symptomatic Vitreous Floaters: Application of Infrared Fundus Photography in Assessing the Treatment Efficacy

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Xiaolei Sun ◽  
Jingyi Tian ◽  
Jinyan Wang ◽  
Jingjing Zhang ◽  
Ying Wang ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Treatment Efficacy ◽  
Pearson Correlation ◽  
Fundus Photography ◽  
Yag Lasers ◽  
Retinal Injury ◽  
Vitreous Floaters ◽  
Visual Function Questionnaire

Background. Vitreous floater is a physically common phenomenon with aging and is related to visual impairment and decrease of quality of life. Nd:YAG vitreolysis is supposed to be an option for resolving floaters, but its clinical efficacy is undefined. We aimed to evaluate the efficacy of Nd:YAG vitreolysis in treating floater semiquantifiably by determining changes of floater areas on infrared fundus photography (IR). Methods. Patients with floaters and those who underwent Nd:YAG vitreolysis were retrospectively summarized from June 2015 to Nov 2017. Intraocular pressure, visual acuity, visual function questionnaire (VFQ-25) scores, and floater areas calculated using Image J software were recorded preoperatively and 6 months after YAG lasers. Results. 50 patients (25 female/25 male, with an average age of 60.34 years) with 55 eyes (29 OD and 26 OS) presenting floaters and underwent YAG vitreolysis treatment were included. Severe symptoms were reported in 17 eyes, moderate in 21 and mild in 17 eyes. No severe Nd:YAG vitreolysis procedure-related complications occurred in all patients except one mild retinal injury. There were no significant changes in intraocular pressure and visual acuity after the laser treatment. 43 eyes had improved symptoms; in 8, floaters had disappeared; and 4 had no changes according to VFQ-25 scores. The median of shadow areas of floaters before operation was 1.41 (0.29–12.85) cm2, which decreased to 0.12 (0–2.77) cm2 after the operations (t=5.849,  P=0.001). The mean VFQ-25 scores increased to 88.54 ± 12.74 from the baseline 71.44 ± 12.77 (t=11.82,  P=0.001). Pearson correlation analysis showed that the shadow areas of floaters were negatively correlated to VFQ-25 scores before (r=−0.73,  P=0.001) and after (r=−0.72,  P=0.001) treatments. Conclusion. Nd:YAG vitreolysis was effective and safe in alleviating the visual symptoms induced by floaters. Quantification of floater shadow areas on infrared fundus photography could serve as an objective index for assessing treatment efficacy of Nd:YAG vitreolysis.

Toxic Damage to the Visual System in Case of Unintentiona

2020 ◽  
pp. 54-60
Author(s):  
E.E. Ioyleva ◽  
◽  
E.S. Kurakina ◽  
E.P. Andrusyakova ◽  
M.A. Saif ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Optic Disc ◽  
Ganglion Cells ◽  
Vitreous Body ◽  
State Institution ◽  
Federal State ◽  
Ophthalmological Examination ◽  
Internal Layers ◽  
Toxic Damage

The patient complained of a severe, yet painless, reduction in vision of both eyes after an accidental intramuscular injection of Klozantrem with a dose of 4.0 ml in S. Fedorov Eye Microsurgery Federal State Institution. The standard ophthalmological examination was performed (OU visual acuity was counting fingers at a distance of 10 cm, OD intraocular pressure was 10mm Hg, OS intraocular pressure was 9 mm Hg, eye movement unremarkable). Biomicroscopy showed both eyes were calm, pale pink conjunctivae, transparent cornea, medium depth anterior chamber, transparent lens. OU ophthalmoscopy showed the optic disc was discolourated, its boundaries were indistinct, arteries and veins were narrowed, macular area of the retina without a visible physical pathology. Perimetry showed the correct light projection. A reduction in the thickness of the external and internal layers of the retina was observed as a result of the OCT of the macular zone OU. OCT showed the thickness of the layer of nerve fibres in the upper and lower nasal segments. OS has the prominence of the optic disc in the vitreous body. The threshold of the electrical sensitivity OU was 300 mkA by electrophysiological research; the electrical latency was not defined. During the MRI scan, the fascinated changes of the cerebral cortex have not been found. Acute optic neuropathy of toxic genesis was diagnosed in both eyes. A course of complex conservative treatment was prescribed: anti-inflammatory, nootropic, metabolic, vitamin therapy, as well as magnetotherapy, electrical stimulation and electrophoresis. As a result of the reported case by patient due to unintentional application of Closantel, we found that toxic damage of the ganglion cells of the retina was initially occurring, resulting in a reduction of the central visual acuity, followed by the development of the optic nerve atrophy. Care must be exercised when dealing with medicines. Potentially, any medicines are toxic and, if used improperly, may cause a number of side effects from the visual and central nervous system.

Icare versus Goldmann in a randomised middle-aged population

2020 ◽  
pp. 112067212092138
Author(s):  
Katri Stoor ◽  
Elina Karvonen ◽  
Pasi Ohtonen ◽  
M Johanna Liinamaa ◽  
Ville Saarela
Keyword(s):  
Intraocular Pressure ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Intraclass Correlation ◽  
Population Based ◽  
Rebound Tonometer ◽  
Goldmann Applanation Tonometer ◽  
Applanation Tonometer ◽  
Screening Study ◽  
The Difference

Purpose The aim of this study was to compare the measurements of intraocular pressure by two tonometers, the Icare rebound tonometer and the Goldmann applanation tonometer, in a randomised screening study. The influence of refraction and central corneal thickness on the measurements was also evaluated. Methods Intraocular pressure was measured with rebound tonometer and Goldmann applanation tonometer in 1266 participants; refraction and central corneal thickness were also determined. One randomised eye of each participant was selected for this report’s analysis. A Bland–Altman plot was used to compare the values obtained with the two devices. Results The correlation between rebound tonometer and Goldmann applanation tonometer was good: the intraclass correlation coefficient (r) between the two methods was 0.735 ( p < 0.001). The mean difference (rebound tonometer–Goldmann applanation tonometer) was 0.11 ± 2.3 mmHg. The difference was not statistically significant (95% confidence interval: 0.11 to 0.13, p = 0.09). With increasing central corneal thickness, not only did intraocular pressure values with both devices increase, but the difference between them also increased. Refraction (spherical equivalent) did not influence intraocular pressure or the rebound tonometer–Goldmann applanation tonometer difference. However, high astigmatism (≥2D) exerted an influence on intraocular pressure values taken with Goldmann applanation tonometer. Conclusion Measurements with rebound tonometer and Goldmann applanation tonometer are relatively uniform although rebound tonometer slightly overestimated intraocular pressure. Both rebound tonometer and Goldmann applanation tonometer and the difference between these devices were affected by central corneal thickness but not by refraction. Higher astigmatism affected Goldmann applanation tonometer more than rebound tonometer. It is concluded that rebound tonometer is a reliable method for measuring intraocular pressure in a population-based screening study.

scholarly journals Evaluation of the New Digital Goldmann Applanation Tonometer for Measuring Intraocular Pressure

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Yuta Sakaue ◽  
Jun Ueda ◽  
Masaaki Seki ◽  
Takayuki Tanaka ◽  
Tetsuya Togano ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Correlation Coefficient ◽  
Pearson’S Correlation ◽  
Pearson’S Correlation Coefficient ◽  
Goldmann Applanation Tonometer ◽  
Applanation Tonometer ◽  
Pearson's Correlation ◽  
The Mean ◽  
The Difference ◽  
Pearson's Correlation Coefficient

Purpose. To compare a new digital Goldmann applanation tonometer (dGAT) that measures intraocular pressure (IOP) in 0.1 mmHg increments to a standard Goldmann applanation tonometer (sGAT).Methods. This study included 116 eyes of 60 subjects. A single examiner first measured IOP in triplicate using either sGAT or dGAT, which was randomly chosen. After a 5-minute interval, the next set of three consecutive IOP was measured using the other GAT.Results. The mean IOP measured with sGAT was 16.27 ± 6.68 mmHg and 16.35 ± 6.69 mmHg with dGAT. Pearson’s correlation coefficient was 0.998 (P<0.01). The subjects were divided into three groups based on the mean IOP: IOP < 14 mmHg, 14–20 mmHg, or >20 mmHg. The Pearson’s correlation coefficient within each group was 0.935, 0.972, and 0.997 (P<0.01), respectively. The difference within the three consecutive IOP measurements (maximum–minimum) for dGAT (0.72 ± 0.34 mmHg) was significantly smaller than those with sGAT (0.92 ± 0.42 mmHg,P<0.01). Even in patients with equal IOP (zero left-right difference) with sGAT (n=30), dGAT detected IOP differences between the left and right eyes (0.47 ± 0.31 mmHg).Conclusion. Compared to sGAT, dGAT measurements are highly reproducible and less variable.

scholarly journals Comparative study of intraocular pressure (IP) in Bangladeshi individuals by contact and non contact technique

2016 ◽  
Vol 8 (1) ◽  
pp. 56
Author(s):  
Sayed Abdul Wadud ◽  
Md. Sharfuddin Ahmad ◽  
Muntasir Bin Shahid
Keyword(s):  
Intraocular Pressure ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Contact Method ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Goldmann Applanation Tonometer ◽  
Applanation Tonometer ◽  
The Mean ◽  
The Difference

<p><strong>Background:</strong> Intraocular pressure (IOP) is one of the most important parameters in the diagnosis and treatment of glaucoma. Glaucoma has been established as the second leading cause of blindness. The treatment of glaucoma focuses mainly on lowering intraocular pressure (IOP). The target IOP is often set to a level 20% to 30% of IOP reduction, and consequent large IOP reduction beyond 30% or even 40% in cases of advanced glaucoma The different methods of tonometery are: Goldman Applanation tonometery, Noncontact (air-puff) tonometery, Perkins tonometery, Tonopen tonometery, Transpalpebral tonometery.</p><p><strong>Objective:</strong> To determine the frequency of accuracy of intraocular pressure (IOP) measured by non-contact (air puff) tonometer compared with Goldmann applanation tonometer.</p><p><strong>Methods:</strong> This was a non-interventional, cross sectional study conducted at a tertiary care centre of Dhaka, Bangladesh. consecutive subjects attending the BSMMU eye OPD were included in the study. IOP was measured by non-contact (air puff) tonometer and a slit lamp mounted GAT in all the subjects. The study samples were selected by convenience sampling who presented for check-up in the Eye Department of community ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka. Bangladesh. Results:A total of 120 eyes in 60 patients were studied. The mean age of the patients was 41.60 year. study population consisted of 24 (40 %) men and 36 (60 %) women. The mean intraocular pressure was 13.52 &amp;13.72 mmHg for GAT, and 16.64 &amp; 17.44 mmHg for Air puff respectively. The range of measurements by GAT was from 10 to 23 mmHg and by Air puff was 12 to 28mmHg. The difference between IOP measured by two instruments were statistically significant (p=0.000).</p><p><strong>Conclusion:</strong> Airpuff tonometer is quick, a non-contact method to measure intraocular pressure and is useful for screening purposes and postoperative case but the measurements should be confirmed with Goldmann applanation tonometer for accurate labelling of intraocular pressure.</p>

Comparison of intraocular pressure obtained by Goldmann applanation tonometer, Corvis ST and an airpuff tonometer in healthy adults

2021 ◽  
pp. 112067212110692
Author(s):  
Efthymios Karmiris ◽  
Konstantinos Tsiripidis ◽  
Panos S Gartaganis ◽  
Styliani Totou ◽  
Maria-Giannoula Vasilopoulou ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Repeated Measures ◽  
Prospective Observational Study ◽  
Test Results ◽  
Corvis St ◽  
Goldmann Applanation Tonometer ◽  
Bland Altman Method ◽  
Repeated Measures Analysis ◽  
Applanation Tonometer ◽  
The Difference

Purpose To assess the agreement among four types of intraocular pressure (IOP) measurements: IOP obtained by Goldmann applanation tonometer (IOP-GAT),IOP obtained by an air-puff tonometer (Nidek NT-510)(IOP-NCT), the non-corrected IOP obtained by the Corneal Visualization Scheimpflug Technology (IOP-Corvis) and the biomechanically corrected IOP obtained by the Corvis ST (bIOP-Corvis) in healthy patients with a broad spectrum of IOP values. Methods: This prospective, observational study recruited 113 healthy individuals. Each patient underwent IOP evaluation via GAT, Nidek NT-510 and Corvis ST. Difference in mean in IOP readings was assessed by one-way repeated-measures analysis of variance (ANOVA).Tonometer intermethod agreement was assessed by the Bland-Altman method. The difference between the four IOP measurements was correlated against corneal (CCT) and age with Pearson’s correlation test. Results: IOP-Corvis showed the highest values (16.59  ±  3.08 mmHg),followed by IOP-NCT (16.05  ±  3.43 mmHg), IOP-GAT (15.62 ± 3.08 mmHg) and bIOP-Corvis (15.10 ± 2.67 mmHg).There were statistically significant differences in IOP measurements among all the ANOVA pairwise comparisons except between IOP-GAT and bIOP-Corvis ( p = 0.07),as well as between IOP-GAT and IOP-NCT ( p = 0.25). Bland Altman analysis revealed a notable bias (all p < 0.05) among IOP-GAT and bIOP-Corvis, IOP-GAT and IOP-Corvis, IOP-GAT and IOP-NCT, bIOP-Corvis and IOP-Corvis, bIOP-Corvis and IOP-NCT,IOP-Corvis and IOP-NCT of 0.51, −0.97, −0.43, −1.49, −0.95, 0.53 mmHg respectively. We observed a strong correlation of the difference between bIOP-Corvis and IOP-Corvis with CCT and patient age. Conclusion: Compared with GAT and Nidek NT-510, the Corvis-derived IOPs were recorded either the highest as IOP-Corvis or the lowest as bIOP-Corvis. Even if the differences among the tonometers were relatively small, the IOP values obtained with the Corvis ST, NCT and GAT were not interchangeable.

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