Solitary Fibrous Tumor of the Retroperitoneal Space

A solitary fibrous tumor develops from mesenchymal cells as a pleural neoplasm, but it is also occasionally reported in extrapleural sites. Retroperitoneal tumors are a group of neoplasms located between muscles and the fascia of the posterior abdominal wall and the parietal peritoneum. Their cytology differs from that of urinary tract organs or adrenals. This case report presents a rare solitary fibrous tumor incidentally found during an ultrasound examination. A 54-year-old male underwent urgent surgery for a tumor located in the left retroperitoneal space. The histologic examination confirmed a solitary fibrous tumor with a 5% Ki67 proliferation index, a 1 MF/10 HPF mitotic activity, and CD34-positive immunostains. A solitary fibrous tumor is a rare retroperitoneal tumor. Its symptoms and signs might resemble those of the classical triad of renal cell carcinoma, although the tumor’s growth phase is typically asymptomatic. Intraoperative diagnosis of a solitary fibrous tumor strongly recommends radical excision.

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Solitary Fibrous Tumor in the Retroperitoneal Space: Report of a Case

Surgery Today ◽

10.1007/s005950200223 ◽

2002 ◽

Vol 32 (12) ◽

pp. 1099-1101 ◽

Cited By ~ 12

Author(s):

Masazumi Kume ◽

Kimihiro Komori ◽

Hiroyuki Inoguchi ◽

Tetsuya Shoji ◽

Tadashi Furuyama ◽

...

Keyword(s):

Solitary Fibrous Tumor ◽

Retroperitoneal Space ◽

Fibrous Tumor

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The Relationship Between The Apparent Diffusion Coefficient and The Ki-67 Proliferation Index in Intracranial Solitary Fibrous Tumor/Hemangiopericytoma

10.21203/rs.3.rs-903739/v1 ◽

2021 ◽

Author(s):

Shenglin Li ◽

Qing Zhou ◽

Peng Zhang ◽

Shize Ma ◽

Caiqiang Xue ◽

...

Keyword(s):

Diffusion Coefficient ◽

Apparent Diffusion Coefficient ◽

Solitary Fibrous Tumor ◽

Proliferation Index ◽

Ki 67 ◽

Solitary Fibrous Tumors ◽

Average Maximum ◽

Apparent Diffusion ◽

Grade Ii ◽

Fibrous Tumor

Abstract Objiective: This study evaluated the value of the apparent diffusion coefficient (ADC) in distinguishing grade II and III intracranial solitary fibrous tumors /hemangiopericytomas and explored the correlation between ADC and Ki-67. Methods The preoperative MRIs of 37 patients treated for solitary fibrous tumor/hemangiopericytoma (grade II, n = 15 and grade III, n = 22) in our hospital from 2011 to October 2020 were retrospectively analyzed. We compared the difference between the minimum, average, maximum, and relative ADCs based on tumor grade and examined the correlation between ADC and Ki-67. Receiver operating characteristic curve analysis was used to analyze the diagnostic efficiency of the ADC. Results There were significant differences in the average, minimum, and relative ADCs between grade II and III patients. The optimal cutoff value for the relative ADC value to differentiate grade II and III tumors was 0.998, which yielded an area under the curve of 0.879. The Ki-67 proliferation indexes of grade II and III tumors were significantly different, and the average (r = -0.427), minimum (r = -0.356), and relative (r = -0.529) ADCs were significantly negatively correlated with the Ki-67 proliferation index. Conclusions ADC can be used to differentiate grade II and III intracranial solitary fibrous tumors/hemangiopericytomas. Our results can be used to formulate a personalized surgical treatment plan before surgery.

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Pathology Consultation Solitary Fibrous Tumor

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348949310200114 ◽

1993 ◽

Vol 102 (1) ◽

pp. 74-76 ◽

Cited By ~ 27

Author(s):

John G. Batsakis ◽

Roger D. Hybels ◽

Adel K. El-Naggar

Keyword(s):

Soft Tissue ◽

Respiratory Tract ◽

Solitary Fibrous Tumor ◽

Surgical Excision ◽

Upper Respiratory Tract ◽

Solitary Fibrous Tumors ◽

Histopathologic Diagnosis ◽

Pleural Neoplasm ◽

Upper Respiratory ◽

Fibrous Tumor

First described as a pleural neoplasm, the solitary fibrous tumor has been reported in a number of extrapleural sites, including the upper respiratory tract. The neoplasm is of mesenchymal origin, exists in benign and malignant forms, and is a histopathologic diagnosis made after exclusion of other soft tissue neoplasms. None of the eight reported sinonasal and nasopharyngeal solitary fibrous tumors have been histologically or biologically malignant. Surgical excision appears to control the tumor at these sites.

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