Synthesis, Characterization and High In Vitro Antitumour Activity
of Novel Triphenyltin Carboxylates
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The synthesis and spectral characterization of six novel triphenyltin compounds are described. The in vitro antitumour activity of three of these compounds against two human tumour cell lines, MCF-7, a mammary tumour, and WiDr, a colon carcinoma, was determined. All three compounds are more active than cis-platin, etoposide and doxorubicin against both tumour cell lines. They are as active as mitomycin C against WiDr, but less active against MCF-7.
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2008 ◽
Vol 6
(12)
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pp. 137
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1989 ◽
Vol 25
(2)
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pp. 271-277
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1990 ◽
Vol 39
(4)
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pp. 787-792
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