Characterization of the cytotoxic properties of the benzimidazole fungicides, benomyl and carbendazim, in human tumour cell lines and primary cultures of patient tumour cells

2010 ◽  
Vol 21 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Daniel Laryea ◽  
Joachim Gullbo ◽  
Anders Isaksson ◽  
Rolf Larsson ◽  
Peter Nygren
Keyword(s):  
Cell Lines ◽  
Tumour Cell ◽  
Primary Cultures ◽  
Tumour Cells ◽  
Human Tumour ◽  
Benzimidazole Fungicides ◽  
Tumour Cell Lines ◽  
Human Tumour Cell Lines

scholarly journals Synthesis, Characterization and High In Vitro Antitumour Activity of Novel Triphenyltin Carboxylates

1994 ◽  
Vol 1 (4) ◽  
pp. 305-309 ◽  
Author(s):  
Marcel Gielen ◽  
Abdelaziz El Khloufi ◽  
Monique Biesemans ◽  
Abdeslam Bouhdid ◽  
Dick de Vos ◽  
...  
Keyword(s):  
Colon Carcinoma ◽  
Cell Lines ◽  
Tumour Cell ◽  
Antitumour Activity ◽  
Human Tumour ◽  
Tumour Cell Lines ◽  
Human Tumour Cell Lines ◽  
Mcf 7

The synthesis and spectral characterization of six novel triphenyltin compounds are described. The in vitro antitumour activity of three of these compounds against two human tumour cell lines, MCF-7, a mammary tumour, and WiDr, a colon carcinoma, was determined. All three compounds are more active than cis-platin, etoposide and doxorubicin against both tumour cell lines. They are as active as mitomycin C against WiDr, but less active against MCF-7.

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