scholarly journals Effect of bile acid enterohepatic circulation on interdigestive migrating motor complex

2004 ◽  
Vol 12 (11) ◽  
pp. 2610-2613
Author(s):  
Zhen-Ni Zhang ◽  
Lei Dong ◽  
Xin Liu ◽  
Yi Li
Keyword(s):  
Bile Acid ◽  
Enterohepatic Circulation ◽  
Migrating Motor Complex ◽  
Motor Complex ◽  
Interdigestive Migrating Motor Complex

Effect of insulin-induced hypoglycaemia on antral, pyloric and duodenal motility in fasting subjects

1991 ◽  
Vol 81 (2) ◽  
pp. 281-285 ◽  
Author(s):  
R. Fraser ◽  
J. Fuller ◽  
M. Horowitz ◽  
J. Dent
Keyword(s):  
Blood Glucose ◽  
Gastric Emptying ◽  
Phase I ◽  
Blood Glucose Concentration ◽  
Migrating Motor Complex ◽  
Control Group ◽  
Motor Complex ◽  
Significant Difference ◽  
Interdigestive Migrating Motor Complex ◽  
Pyloric Motility

1. Hyperglycaemia alters gastric motility and delays gastric emptying. By contrast, there is little information regarding the effect of sub-normal blood glucose concentrations on gastric and, in particular, pyloric motility, although limited data suggest that hypoglycaemia is associated with accelerated gastric emptying despite an apparently increased basal pyloric pressure. 2. To determine the effects of hypoglycaemia on pyloric motility, we compared the effects of an intravenous injection of insulin (0.15 units/kg) with those of a placebo injection of saline in eight healthy human volunteers during phase I of the interdigestive migrating motor complex. 3. All subjects developed profound hypoglycaemia (mean blood glucose concentration 1.6 mmol/l compared with 4.0 mmol/l in the control group). 4. There was no significant difference in the number of antral (9 versus 7, P = 0.34), pyloric (3 versus 0, P = 0.31) or duodenal (21 versus 13, P = 0.42) pressure waves or in the basal pyloric pressure (0.3 mmHg versus 0.1 mmHg, P = 0.37) in the 45 min after insulin injection (hypoglycaemia) when compared with the 45 min after saline injection (euglycaemia). In both the euglycaemic and hypoglycaemic studies there was a time-dependent increase in the numbers of antral and duodenal waves consistent with the expected changes in the interdigestive migrating motor complex. 5. These results indicate that insulin-induced hypoglycaemia has no significant effect on pyloric motility during phase I of the interdigestive migrating motor complex.

(Gln4)-neurotensin inhibits the interdigestive migrating motor complex in man

1980 ◽  
Vol 1 ◽  
pp. S114
Author(s):  
K. Thor ◽  
Å. Rökaeus ◽  
L. Kager ◽  
K. Folkers ◽  
S. Rosell
Keyword(s):  
Migrating Motor Complex ◽  
Motor Complex ◽  
Interdigestive Migrating Motor Complex

scholarly journals Interdigestive Migrating Motor Complex (IMC) is Co-Regulated With Ghrelin and Motilin in Conscious Dogs

2011 ◽  
Vol 140 (5) ◽  
pp. S-600
Author(s):  
Atsushi Ogawa ◽  
Erito Mochiki ◽  
Mitsuhiro Yanai ◽  
Hiroki Morita ◽  
Yoshitaka Toyomasu ◽  
...  
Keyword(s):  
Migrating Motor Complex ◽  
Conscious Dogs ◽  
Motor Complex ◽  
Interdigestive Migrating Motor Complex

Studies on the interdigestive (migrating) motor complex in man

1978 ◽  
pp. 3-8 ◽  
Author(s):  
G. Vantrappen ◽  
J. Janssens ◽  
J. Hellemans ◽  
N. Christofides ◽  
S. Bloom
Keyword(s):  
Migrating Motor Complex ◽  
Motor Complex ◽  
Interdigestive Migrating Motor Complex

Fasting and postprandial hepatic bile flow in unanesthetized opossums

1990 ◽  
Vol 259 (5) ◽  
pp. G745-G752 ◽  
Author(s):  
I. Takahashi ◽  
M. K. Kern ◽  
W. J. Dodds ◽  
W. J. Hogan ◽  
R. D. Layman ◽  
...  
Keyword(s):  
Bile Acid ◽  
Bile Flow ◽  
Common Duct ◽  
Enterohepatic Circulation ◽  
Phase Iii ◽  
Hepatic Bile ◽  
Bipolar Electrodes ◽  
Motor Complex ◽  
The Common ◽  
The Relationship

In conscious opossums, we evaluated the relationship between hepatic bile flow and the intestinal motor function during fasting as well as after feeding. In six opossums, bipolar electrodes were implanted from the gastric antrum to the terminal ileum. After cholecystectomy, the common duct was ligated, and a catheter was tied into the proximal common duct for collecting hepatic bile. During subsequent studies, hepatic bile flow was measured, and bile was returned to the duodenum through an externalized duodenal catheter. Cyclic increases in bile flow during fasting did not show a close correlate with the duodenal migratory motor complex (MMC) cycle. Rather, bile flow showed peak values [0.11 +/- 0.02 (SE) ml/min] when phase III MMC activity reached the midileum. Hepatic bile flow correlated closely with the amount of bile acid secreted by the liver. When the bile acid pool was depleted by diverting bile from the intestine, hepatic secretion of bile fell to uniformly low values of approximately 0.04 ml/min that did not show cyclic variation. Hepatic bile flow after feeding increased to a maximal value of 0.12 +/- 0.01 ml/min at 90 min. We conclude that increases in hepatic bile flow during fasting and after meals are determined mainly by variations in intestinal motor activity that alter small bowel transit and thereby affect the enterohepatic circulation of bile acids.

W1366 Interdigestive Migrating Motor Complex Is Regulated By the Interaction Between Motilin and 5-HT of the Duodenal Mucosa in Conscious Dogs

2008 ◽  
Vol 134 (4) ◽  
pp. A-689
Author(s):  
Hitoshi Nakajima ◽  
Erito Mochiki ◽  
Hiroshi Taniguchi ◽  
Hajime Ariga ◽  
Cindy Chen ◽  
...  
Keyword(s):  
Duodenal Mucosa ◽  
Migrating Motor Complex ◽  
Conscious Dogs ◽  
Motor Complex ◽  
Interdigestive Migrating Motor Complex
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