Evaluation of the Antitumor Efficacy, Pharmacokinetics, and Pharmacodynamics of the Histone Deacetylase Inhibitor Depsipeptide in Childhood Cancer Models In vivo

Antitumor Efficacy ◽

Pharmacokinetics And Pharmacodynamics ◽

Cancer Models ◽

The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-010-1495-6 ◽

2010 ◽

Vol 68 (2) ◽

pp. 389-398 ◽

Cited By ~ 16

Author(s):

Young-Soon Na ◽

Kyung-Ah Jung ◽

Seung-Mi Kim ◽

Yong Sang Hong ◽

Min-Hee Ryu ◽

...

Keyword(s):

Colon Cancer ◽

Histone Deacetylase ◽

Cancer Models ◽

The histone deacetylase inhibitor FK228 increases the efficacy of adenovirus-mediated p53 family gene therapy in in Vitro and in Vivo human cancer models

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3160 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3160-3160

Author(s):

Y. Sasaki ◽

Y. Oshima ◽

H. Mita ◽

Y. Naishiro ◽

M. Toyota ◽

...

Keyword(s):

Gene Therapy ◽

Histone Deacetylase ◽

Human Cancer ◽

P53 Family ◽

Cancer Models ◽

Deacetylase Inhibitor ◽

Family Gene

In vitro and in vivo histone deacetylase inhibitor therapy with vorinostat and paclitaxel in ovarian cancer models: Does timing matter?

Gynecologic Oncology ◽

10.1016/j.ygyno.2010.06.030 ◽

2010 ◽

Vol 119 (2) ◽

pp. 351-357 ◽

Cited By ~ 17

Author(s):

Susan C. Modesitt ◽

Sarah J. Parsons

Keyword(s):

Ovarian Cancer ◽

Histone Deacetylase ◽

Inhibitor Therapy ◽

Cancer Models ◽

CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-06-0042 ◽

2006 ◽

Vol 5 (7) ◽

pp. 1693-1701 ◽

Cited By ~ 19

Author(s):

Z. Alexander Cao ◽

Kathryn E. Bass ◽

Sriram Balasubramanian ◽

Liang Liu ◽

Brian Schultz ◽

...

Keyword(s):

Histone Deacetylase ◽

Broad Spectrum ◽

Antiangiogenic Activity ◽

Tissue-Targeted In Vivo Gene Transfer Coupled with Histone Deacetylase Inhibitor Depsipeptide (FK228) Enhances Adenoviral Infection in Rat Renal Cancer Allograft Model Systems

Urology ◽

10.1016/j.urology.2007.09.022 ◽

2007 ◽

Vol 70 (6) ◽

pp. 1230-1236 ◽

Cited By ~ 5

Author(s):

Minoru Kobayashi ◽

Takashi Okada ◽

Takashi Murakami ◽

Keiya Ozawa ◽

Eiji Kobayashi ◽

...

Keyword(s):

Gene Transfer ◽

Histone Deacetylase ◽

Renal Cancer ◽

Model Systems ◽

Adenoviral Infection ◽

Deacetylase Inhibitor ◽

In Vivo Gene Transfer

Synergistic In vivo Antitumor Effect of the Histone Deacetylase Inhibitor MS-275 in Combination with Interleukin 2 in a Murine Model of Renal Cell Carcinoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-0014 ◽

2007 ◽

Vol 13 (15) ◽

pp. 4538-4546 ◽

Cited By ~ 59

Author(s):

Yukihiko Kato ◽

Kiyoshi Yoshimura ◽

Tahiro Shin ◽

Henk Verheul ◽

Hans Hammers ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Histone Deacetylase ◽

Murine Model ◽

Renal Cell ◽

Antitumor Effect ◽

Interleukin 2 ◽

HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32830efbeb ◽

2008 ◽

Vol 19 (9) ◽

pp. 849-857 ◽

Cited By ~ 16

Author(s):

Dennis Wegener ◽

Hedwig E. Deubzer ◽

Ina Oehme ◽

Till Milde ◽

Christian Hildmann ◽

...

Keyword(s):

Childhood Cancer ◽

Cancer Cells ◽

Histone Deacetylase ◽

Antitumoral Activity ◽

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Journal of Hepatology ◽

10.1016/j.jhep.2011.07.013 ◽

2012 ◽

Vol 56 (1) ◽

pp. 176-183 ◽

Cited By ~ 32

Author(s):

Huanjie Shao ◽

Chun Gao ◽

Haikuo Tang ◽

Hao Zhang ◽

Lewis R. Roberts ◽

...

Keyword(s):

Histone Deacetylase ◽

Dual Targeting ◽

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo

Biochemical Pharmacology ◽

10.1016/s0006-2952(02)01261-3 ◽

2002 ◽

Vol 64 (7) ◽

pp. 1079-1090 ◽

Cited By ~ 63

Author(s):

Yuka Sasakawa ◽

Yoshinori Naoe ◽

Takeshi Inoue ◽

Tatsuya Sasakawa ◽

Masahiko Matsuo ◽

...

Keyword(s):

Histone Deacetylase ◽

Deacetylase Inhibitor ◽

Human Lymphoma

Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53

International Journal of Biological Sciences ◽

10.7150/ijbs.45505 ◽

2020 ◽

Vol 16 (16) ◽

pp. 3184-3199

Author(s):

Batsaikhan Buyandelger ◽

Eli E Bar ◽

Kuo-Sheng Hung ◽

Ruei-Ming Chen ◽

Yung-Hsiao Chiang ◽

...

Keyword(s):

Histone Deacetylase ◽

Deacetylase Inhibitor ◽

Glioma Growth