The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models

Cancer Models ◽

The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-006-0374-7 ◽

2006 ◽

Vol 60 (2) ◽

pp. 275-283 ◽

Cited By ~ 41

Author(s):

Anthony Tumber ◽

Laura S. Collins ◽

Kamille Dumong Petersen ◽

Annemette Thougaard ◽

Sanne J. Christiansen ◽

...

Keyword(s):

Colon Cancer ◽

Cell Growth ◽

Histone Deacetylase ◽

Cancer Cell ◽

Colon Cancer Cell ◽

Cancer Cell Growth ◽

The histone deacetylase inhibitor FK228 increases the efficacy of adenovirus-mediated p53 family gene therapy in in Vitro and in Vivo human cancer models

Journal of Clinical Oncology ◽

10.1200/jco.2005.23.16_suppl.3160 ◽

2005 ◽

Vol 23 (16_suppl) ◽

pp. 3160-3160

Author(s):

Y. Sasaki ◽

Y. Oshima ◽

H. Mita ◽

Y. Naishiro ◽

M. Toyota ◽

...

Keyword(s):

Gene Therapy ◽

Histone Deacetylase ◽

Human Cancer ◽

P53 Family ◽

Cancer Models ◽

Deacetylase Inhibitor ◽

Family Gene

In vitro and in vivo histone deacetylase inhibitor therapy with vorinostat and paclitaxel in ovarian cancer models: Does timing matter?

Gynecologic Oncology ◽

10.1016/j.ygyno.2010.06.030 ◽

2010 ◽

Vol 119 (2) ◽

pp. 351-357 ◽

Cited By ~ 17

Author(s):

Susan C. Modesitt ◽

Sarah J. Parsons

Keyword(s):

Ovarian Cancer ◽

Histone Deacetylase ◽

Inhibitor Therapy ◽

Cancer Models ◽

CRA-026440: a potent, broad-spectrum, hydroxamic histone deacetylase inhibitor with antiproliferative and antiangiogenic activity in vitro and in vivo

Molecular Cancer Therapeutics ◽

10.1158/1535-7163.mct-06-0042 ◽

2006 ◽

Vol 5 (7) ◽

pp. 1693-1701 ◽

Cited By ~ 19

Author(s):

Z. Alexander Cao ◽

Kathryn E. Bass ◽

Sriram Balasubramanian ◽

Liang Liu ◽

Brian Schultz ◽

...

Keyword(s):

Histone Deacetylase ◽

Broad Spectrum ◽

Antiangiogenic Activity ◽

Evaluation of the Antitumor Efficacy, Pharmacokinetics, and Pharmacodynamics of the Histone Deacetylase Inhibitor Depsipeptide in Childhood Cancer Models In vivo

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-05-1225 ◽

2006 ◽

Vol 12 (1) ◽

pp. 223-234 ◽

Cited By ~ 67

Author(s):

Claire Graham ◽

Chandra Tucker ◽

Jeremy Creech ◽

Edward Favours ◽

Catherine A. Billups ◽

...

Keyword(s):

Childhood Cancer ◽

Histone Deacetylase ◽

Antitumor Efficacy ◽

Pharmacokinetics And Pharmacodynamics ◽

Cancer Models ◽

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Journal of Hepatology ◽

10.1016/j.jhep.2011.07.013 ◽

2012 ◽

Vol 56 (1) ◽

pp. 176-183 ◽

Cited By ~ 32

Author(s):

Huanjie Shao ◽

Chun Gao ◽

Haikuo Tang ◽

Hao Zhang ◽

Lewis R. Roberts ◽

...

Keyword(s):

Histone Deacetylase ◽

Dual Targeting ◽

Effects of FK228, a novel histone deacetylase inhibitor, on human lymphoma U-937 cells in vitro and in vivo

Biochemical Pharmacology ◽

10.1016/s0006-2952(02)01261-3 ◽

2002 ◽

Vol 64 (7) ◽

pp. 1079-1090 ◽

Cited By ~ 63

Author(s):

Yuka Sasakawa ◽

Yoshinori Naoe ◽

Takeshi Inoue ◽

Tatsuya Sasakawa ◽

Masahiko Matsuo ◽

...

Keyword(s):

Histone Deacetylase ◽

Deacetylase Inhibitor ◽

Human Lymphoma

Histone deacetylase inhibitor MPT0B291 suppresses Glioma Growth in vitro and in vivo partially through acetylation of p53

International Journal of Biological Sciences ◽

10.7150/ijbs.45505 ◽

2020 ◽

Vol 16 (16) ◽

pp. 3184-3199

Author(s):

Batsaikhan Buyandelger ◽

Eli E Bar ◽

Kuo-Sheng Hung ◽

Ruei-Ming Chen ◽

Yung-Hsiao Chiang ◽

...

Keyword(s):

Histone Deacetylase ◽

Deacetylase Inhibitor ◽

Glioma Growth

Growth inhibition of pancreatic cancer cells by histone deacetylase inhibitor belinostat through suppression of multiple pathways including HIF, NFkB, and mTOR signaling in vitro and in vivo

Molecular Carcinogenesis ◽

10.1002/mc.22024 ◽

2013 ◽

Vol 53 (9) ◽

pp. 722-735 ◽

Cited By ~ 37

Author(s):

Wenwen Chien ◽

Dhong Hyun Lee ◽

Yun Zheng ◽

Peer Wuensche ◽

Rosie Alvarez ◽

...

Keyword(s):

Pancreatic Cancer ◽

Growth Inhibition ◽

Cancer Cells ◽

Histone Deacetylase ◽

Mtor Signaling ◽

Pancreatic Cancer Cells ◽

Histone deacetylase inhibitor NVP-LAQ824 has significant activity against myeloid leukemia cells in vitro and in vivo

Leukemia ◽

10.1038/sj.leu.2403519 ◽

2004 ◽

Vol 18 (12) ◽

pp. 1951-1963 ◽

Cited By ~ 44

Author(s):

E Weisberg ◽

L Catley ◽

J Kujawa ◽

P Atadja ◽

S Remiszewski ◽

...

Keyword(s):

Histone Deacetylase ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Significant Activity ◽