Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis

Kinase Inhibitor ◽

Quantitative Image Analysis ◽

Pdgf Receptor ◽

Quantitative Image

The Synergistic Action of a VEGF-Receptor Tyrosine-Kinase Inhibitor and a Sensitizing PDGF-Receptor Blocker Depends upon the Stage of Vascular Maturation

Microcirculation ◽

10.1080/10739680701370021 ◽

2007 ◽

Vol 14 (8) ◽

pp. 813-825 ◽

Cited By ~ 17

Author(s):

Ruslan Hlushchuk ◽

Oliver Baum ◽

Guenther Gruber ◽

Jeanette Wood ◽

Valentin Djonov

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Synergistic Action ◽

Receptor Blocker ◽

Vegf Receptor ◽

Pdgf Receptor ◽

Vascular Maturation

Restenosis Following Angioplasty in the Swine Coronary Artery Is Inhibited By an Orally Active PDGF-Receptor Tyrosine Kinase Inhibitor, RPR101511A

Circulation ◽

10.1161/01.cir.99.25.3292 ◽

1999 ◽

Vol 99 (25) ◽

pp. 3292-3299 ◽

Cited By ~ 54

Author(s):

Glenda Bilder ◽

Tara Wentz ◽

Robert Leadley ◽

Dilip Amin ◽

Lisa Byan ◽

...

Keyword(s):

Coronary Artery ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Pdgf Receptor ◽

Orally Active

CM082, a novel VEGF receptor tyrosine kinase inhibitor, can inhibit angiogenesis in vitro and in vivo

Microvascular Research ◽

10.1016/j.mvr.2021.104146 ◽

2021 ◽

Vol 136 ◽

pp. 104146

Author(s):

Handong Dan ◽

Xinlan Lei ◽

Xin Huang ◽

Ning Ma ◽

Yiqiao Xing ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Vegf Receptor ◽

Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, shows efficacy in the treatment of HER2 amplified carcinosarcoma in vitro and in vivo

Gynecologic Oncology ◽

10.1016/j.ygyno.2015.01.142 ◽

2015 ◽

Vol 137 ◽

pp. 61

Author(s):

C.L. Schwab ◽

D.P. English ◽

J.D. Black ◽

S. Lopez ◽

S. Bellone ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Erbb Receptor ◽

Erbb Receptor Tyrosine Kinase

PDGF receptor tyrosine kinase inhibitor suppresses mesangial cell proliferation involving STAT3 activation

Clinical & Experimental Immunology ◽

10.1111/j.1365-2249.2006.03073.x ◽

2006 ◽

Vol 144 (2) ◽

pp. 353-361 ◽

Cited By ~ 22

Author(s):

T. Hirai ◽

T. Masaki ◽

M. Kuratsune ◽

N. Yorioka ◽

N. Kohno

Keyword(s):

Cell Proliferation ◽

Tyrosine Kinase ◽

Mesangial Cell ◽

Kinase Inhibitor ◽

Pdgf Receptor ◽

Mesangial Cell Proliferation

The Effect Of Masitinib, A C-kit/PDGF Receptor Tyrosine Kinase Inhibitor, On IgE And Ventilator Parameters In Experimental Feline Asthma

10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4076 ◽

2011 ◽

Author(s):

Vamsi P. Guntur ◽

Tekla M. Lee-Fowler ◽

John Dodam ◽

Leah A. Cohn ◽

Amy E. DeClue ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Pdgf Receptor ◽

Masitinib, a c-kit/PDGF receptor tyrosine kinase inhibitor, improves disease control in severe corticosteroid-dependent asthmatics

Allergy ◽

10.1111/j.1398-9995.2009.02122.x ◽

2009 ◽

Vol 64 (8) ◽

pp. 1194-1201 ◽

Cited By ~ 87

Author(s):

M. Humbert ◽

F. de Blay ◽

G. Garcia ◽

A. Prud’homme ◽

C. Leroyer ◽

...

Keyword(s):

Tyrosine Kinase ◽

Disease Control ◽

Kinase Inhibitor ◽

Pdgf Receptor ◽

165 AZD2171, a potent VEGF receptor tyrosine kinase inhibitor, combined with mechanistically distinct antitumor therapies in vivo

European Journal of Cancer Supplements ◽

10.1016/s1359-6349(04)80173-3 ◽

2004 ◽

Vol 2 (8) ◽

pp. 52 ◽

Cited By ~ 1

Author(s):

S. Wedge ◽

J. Kendrew ◽

P.J. Valentine ◽

S.R. Brave ◽

S. Barnett ◽

...

Keyword(s):

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Vegf Receptor ◽

Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor

10.32388/jfobd7 ◽

2020 ◽

Author(s):

Keyword(s):

Epidermal Growth Factor Receptor ◽

Growth Factor ◽

Epidermal Growth Factor ◽

Tyrosine Kinase ◽

Kinase Inhibitor ◽

Growth Factor Receptor ◽

Epidermal Growth

Delayed Therapy with Receptor Tyrosine Kinase Inhibitor Nintedanib Diminished Chronic Rejection in a Murine Lung Transplant Model

10.1055/s-0041-1725623 ◽

2021 ◽

Author(s):

J. Mauer ◽

A. Kuckhahn ◽

J. Distler ◽

B. Spriewald ◽

M. Ramsperger-Gleixner ◽

...

Keyword(s):

Tyrosine Kinase ◽

Chronic Rejection ◽

Lung Transplant ◽

Kinase Inhibitor ◽

Murine Lung ◽

Transplant Model