Abstract 1077: Bufalin inhibited cell proliferation and expression of insulin-like growth factor 2 and type 1 receptor in human colorectal cancer cells

2012 ◽  
Author(s):  
Yong Zhang ◽  
Dian-Xu Feng ◽  
Ronghua Zhao ◽  
Chao Chen ◽  
Jie Wang ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Proliferation ◽  
Growth Factor ◽  
Cancer Cells ◽  
Insulin Like Growth Factor ◽  
Human Colorectal Cancer ◽  
Colorectal Cancer Cells ◽  
Human Colorectal Cancer Cells

scholarly journals Protecting microRNAs from RNase degradation with steric DNA nanostructures

2017 ◽  
Vol 8 (2) ◽  
pp. 1062-1067 ◽  
Author(s):  
H. Qian ◽  
C. Y. Tay ◽  
M. I. Setyawati ◽  
S. L. Chia ◽  
D. S. Lee ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cell Proliferation ◽  
Cancer Cells ◽  
Cancer Cell Proliferation ◽  
Dna Nanostructures ◽  
Human Colorectal Cancer ◽  
Dna Nanostructure ◽  
Colorectal Cancer Cells ◽  
Therapeutic Platform ◽  
Human Colorectal Cancer Cells

A DNA nanostructure bearing a “Shuriken” shape is designed to deliver, protect and activate microRNA-145 functionality in human colorectal cancer cells. This novel DNA nanostructure enabled therapeutic platform greatly suppresses cancer cell proliferation and tumor growth.

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