Abstract 4111: SDF1/CXCR4 regulates stiffness of bone marrow stromal cell through RhoA and Rac1 GTPases pathway to support myeloma cell proliferation in multiple myeloma.

2013 ◽  
Author(s):  
Dan Wu ◽  
Jing Su ◽  
Qianqian Song ◽  
Xiaobo Zhou
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Cell Proliferation ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Myeloma Cell ◽  
Marrow Stromal Cell

Bone marrow stromal cell–derived exosomes as communicators in drug resistance in multiple myeloma cells

Blood ◽  
2014 ◽  
Vol 124 (4) ◽  
pp. 555-566 ◽  
Author(s):  
Jinheng Wang ◽  
An Hendrix ◽  
Sophie Hernot ◽  
Miguel Lemaire ◽  
Elke De Bruyne ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Cell Proliferation ◽  
Drug Resistance ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Myeloma Cells ◽  
Marrow Stromal Cell ◽  
Key Points

Key Points BMSCs and MM cells mutually communicate through exosomes, which carry selective cytokines. BMSC-derived exosomes favor MM cell proliferation, migration, and survival and induce drug resistance to bortezomib.

The IL-6 receptor antagonist SANT-7 overcomes bone marrow stromal cell-mediated drug resistance of multiple myeloma cells

2001 ◽  
Vol 93 (5) ◽  
pp. 674-680 ◽  
Author(s):  
Dirk H�nemann ◽  
Manik Chatterjee ◽  
Rocco Savino ◽  
Kurt Bommert ◽  
Renate Burger ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Drug Resistance ◽  
Receptor Antagonist ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Myeloma Cells ◽  
Marrow Stromal Cell

Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat

2003 ◽  
Vol 73 (6) ◽  
pp. 778-786 ◽  
Author(s):  
Jieli Chen ◽  
Yi Li ◽  
Mark Katakowski ◽  
Xiaoguang Chen ◽  
Lei Wang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Female Rat ◽  
Marrow Stromal Cell

scholarly journals Bone marrow stromal cell-fueled multiple myeloma growth and osteoclastogenesis are sustained by protein kinase CK2

Leukemia ◽  
2014 ◽  
Vol 28 (10) ◽  
pp. 2094-2097 ◽  
Author(s):  
S Manni ◽  
D Toscani ◽  
E Mandato ◽  
A Brancalion ◽  
L Quotti Tubi ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Bone Marrow ◽  
Protein Kinase ◽  
Protein Kinase Ck2 ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell ◽  
Kinase Ck2

Multipotent bone marrow stromal cell therapy promotes endogenous cell proliferation following ischemic stroke

2015 ◽  
Vol 42 (11) ◽  
pp. 1158-1167 ◽  
Author(s):  
Gila Pirzad Jahromi ◽  
Alireza Shabanzadeh Pirsaraei ◽  
Seyed Shahabeddin Sadr ◽  
Golamreza Kaka ◽  
Mahvash Jafari ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Ischemic Stroke ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell
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