Abstract 1384: Promoter methylation of tumor suppressor genes in convalescent saliva samples from patients with head and neck squamous cell carcinoma

Author(s):  
Semra Demokan ◽  
Jatinder Kaur ◽  
Alice Y. Chuang ◽  
Wojciech K. Mydlarz ◽  
Kavita M. Pattani ◽  
...  
2008 ◽  
Vol 68 (12) ◽  
pp. 4494-4499 ◽  
Author(s):  
Kristi L. Bennett ◽  
Matthew Karpenko ◽  
Mau-ting Lin ◽  
Rainer Claus ◽  
Khelifa Arab ◽  
...  

2010 ◽  
Vol 10 (7) ◽  
pp. 689-693 ◽  
Author(s):  
Dong Jin Lee ◽  
Frank Schönleben ◽  
Victoria E. Banuchi ◽  
Wanglong Qiu ◽  
Lanny G. Close ◽  
...  

2013 ◽  
Vol 32 (1) ◽  
pp. 3-11 ◽  
Author(s):  
Ji-Sheng Li ◽  
Jian-Ming Ying ◽  
Xiu-Wen Wang ◽  
Zhao-Hui Wang ◽  
Qian Tao ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Xiaohan Li ◽  
Keiji Kikuchi ◽  
Yasuo Takano

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer in the world. The evolution and progression of HNSCC are considered to result from multiple stepwise alterations of cellular and molecular pathways in squamous epithelium. Recently, inhibitor of growth gene (ING) family consisting of five genes,ING1toING5, was identified as a new tumor suppressor gene family that was implicated in the downregulation of cell cycle and chromatin remodeling. In contrast, it has been shown thatING1andING2play an oncogenic role in some cancers, this situation being similar to TGF-β. In HNSCC, theINGfamily has been reported to be downregulated, and ING translocation from the nucleus to the cytoplasm may be a critical event for carcinogenesis. In this paper, we describe our recent results and briefly summarize current knowledge regarding the biologic functions ofINGin HNSCC.


2017 ◽  
Vol 58 (4) ◽  
pp. 459-465 ◽  
Author(s):  
Abeer A. Alsofyani ◽  
Rawiah A. Alsiary ◽  
Alaa Samkari ◽  
Baraa T. Alhaj-Hussain ◽  
Jalaluddin Azam Khan ◽  
...  

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