Abstract 2520: Detection of transcriptional active HPV 16/18 in patients with oropharyngeal squamous cell carcinoma by dual immunohistochemistry p16INK4and in situ hybridization E6/E7 mRNA in archival material older than 25 years

2021 ◽  
Author(s):  
Stian Tornaas ◽  
Siren Fromreid ◽  
Hans Jørgen Aarstad ◽  
Olav Karsten Vintermyr ◽  
Daniela Elena Costea ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
In Situ Hybridization ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Hpv 16 ◽  
Archival Material

In situ hybridization for high risk HPV E6/E7 mRNA in oropharyngeal squamous cell carcinoma

2021 ◽  
Vol 42 (1) ◽  
pp. 102782
Author(s):  
Krish Suresh ◽  
Parth V. Shah ◽  
Sydney Coates ◽  
Borislav A. Alexiev ◽  
Sandeep Samant
Keyword(s):  
Squamous Cell Carcinoma ◽  
In Situ Hybridization ◽  
High Risk ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Hpv E6 ◽  
High Risk Hpv

scholarly journals Novel Herpesvirus Associated With Oropharyngeal Squamous Cell Carcinoma in Smooth Green Snakes (Opheodrys vernalis)

2019 ◽  
Vol 56 (4) ◽  
pp. 630-635
Author(s):  
Jessica N. Lovstad ◽  
Robert J. Ossiboff ◽  
Michael J. Kinsel ◽  
Kathryn C. Gamble
Keyword(s):  
Squamous Cell Carcinoma ◽  
In Situ Hybridization ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Conventional Polymerase Chain Reaction ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Ex Situ ◽  
Neoplastic Tissue ◽  
Close Proximity

During a 19-month period, 5 smooth green snakes ( Opheodrys vernalis) maintained as an ex situ conservation colony presented with rapid clinical progression of locally invasive oropharyngeal squamous cell carcinoma. All 5 originated from the same wild source and were housed together or in close proximity. An infectious cause was considered likely, and nested conventional polymerase chain reaction (PCR) and in situ hybridization confirmed the presence of a novel alphaherpesvirus, Opheodrys herpesvirus 1, in the neoplastic tissue in 4 of the 5 snakes. Retrospective screening of previously submitted smooth green snakes by in situ hybridization did not detect virus in prior submissions from the colony. This report documents molecular characterization of an ophidian herpesvirus as well as colocalization of its viral nucleic acid with neoplastic transformation in snakes.

Fluorescence in situ hybridization for detecting TP16MTS1/CDK41 gene deletions in squamous cell carcinoma of the head and neck

2003 ◽  
Vol 141 (1) ◽  
pp. 49-55 ◽  
Author(s):  
Ali Namazie ◽  
Sassan Alavi ◽  
Neema Aghamohammadi ◽  
Mazda Aghamohammadi ◽  
Thomas C Calcaterra ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Gene Deletions
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