ABSTRACT
To report a case of anaplastic thyroid carcinoma (ATC) with huge ulcer and to review our experience with these aggressive tumors in our hospital. We retrospectively reviewed the presentation, treatment and survival of all the patients who were diagnosed with ATC at Hospital Raja Perempuan Zainab II (HRPZ II), Kota Bharu, Malaysia from 2004 to 2010. A 63-year-old woman presented to outpatient clinic with history of anterior neck swelling for more than 10 years. She complained of rapid increase in size with huge ulcer and associated with hoarseness of voice and shortness of breath over 1 month period. She was investigated and the diagnosis of ATC was established. However, she refused for any surgical intervention and eventually succumbed during the palliative treatment 5 months later. ATC is a very rare thyroid cancer and usually presents at a very late stage with significant morbidity and mortality. Early detection, new therapeutic strategies and more studies especially based on molecular approaches may probably more helpful for better survival results in the future.
How to cite this article
Sze-How NG, Imisairi AH. The Aggressive Anaplastic Thyroid Carcinoma: A Case Report and Institutional Review. World J Endocr Surg 2012;4(1):20-22.