Localization and linkage of three polymorphic DNA sequences on human chromosome 20

1987 ◽  
Vol 44 (2-3) ◽  
pp. 112-117 ◽  
Author(s):  
P.J. Goodfellow ◽  
A.M.V. Duncan ◽  
L.A. Farrer ◽  
J.J.A. Holden ◽  
B.N. White ◽  
...  
1976 ◽  
Vol 16 (1-5) ◽  
pp. 420-421 ◽  
Author(s):  
Meera Khan ◽  
P.L. Pearson ◽  
L.L.L. Wijnen ◽  
B.A. Doppert ◽  
A. Westerveld ◽  
...  

1982 ◽  
Vol 155 (4) ◽  
pp. 1019-1024 ◽  
Author(s):  
D L Slate ◽  
P D'Eustachio ◽  
D Pravtcheva ◽  
A C Cunningham ◽  
S Nagata ◽  
...  

To determine the chromosomal location of the human alpha interferon genes, we scored a series of human/rodent somatic cell hybrids for the presence of DNA sequences hybridizing to an alpha 1 interferon DNA probe. The presence of human chromosome 9 in a hybrid correlated with the presence of a family of alpha interferon genes.


Genomics ◽  
1992 ◽  
Vol 12 (2) ◽  
pp. 183-189 ◽  
Author(s):  
Jamilé Hazan ◽  
Christopher Dubay ◽  
Marie-Pascale Pankowiak ◽  
Noëlle Becuwe ◽  
Jean Weissenbach

1994 ◽  
Vol 10 (4) ◽  
pp. 267-274 ◽  
Author(s):  
Ursula A. Germann ◽  
Patricia V. Schoenlein ◽  
Drazen B. Zimonjic ◽  
Nicholas C. Popescu ◽  
Ira Pastan ◽  
...  

Diabetes ◽  
1992 ◽  
Vol 41 (1) ◽  
pp. 88-92 ◽  
Author(s):  
D. W. Bowden ◽  
T. C. Gravius ◽  
G. Akots ◽  
S. S. Fajans

1986 ◽  
Vol 6 (11) ◽  
pp. 3826-3830 ◽  
Author(s):  
G P Bates ◽  
B J Wainwright ◽  
R Williamson ◽  
S D Brown

A bank of cloned DNA sequences from the distal half of the short arm of human chromosome 2 was generated by using microdissection and microcloning techniques. DNA was purified from 106 chromosomal fragments, manually dissected from peripheral lymphocytes in metaphase, and cloned into the EcoRI site of lambda gt10. A total of 257 putative recombinants were recovered, of which 41% were found to contain human inserts. The mean insert size was 380 base pairs (median size, 83 base pairs), and fewer than 10% of the clones contained highly repetitive sequences. All single-copy sequences examined were shown to map to the short arm of chromosome 2 by using hybrid panels. This technique provides a rapid method of isolating probes specific to a human subchromosomal region to generate linked markers to genetic diseases for which the chromosomal location is known.


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