Parathyroid Hormone-Related Peptide-Secreting Pancreatic Neuroendocrine Tumours: Case Series and Literature Review

2008 ◽  
Vol 89 (1) ◽  
pp. 48-55 ◽  
Author(s):  
Rajaventhan Srirajaskanthan ◽  
Mary McStay ◽  
Christos Toumpanakis ◽  
Tim Meyer ◽  
Martyn E. Caplin
2021 ◽  
Vol 14 (4) ◽  
pp. e240786
Author(s):  
Benjamin Ferrel ◽  
Jan Franko ◽  
May C Tee

An asymptomatic 68-year-old woman who presented with an isolated hypercalcaemia was diagnosed with a rare, previously unsuspected parathyroid hormone-related peptide (PTHrP)-producing pancreatic neuroendocrine tumour. She underwent an extensive operation including vascular resection and reconstruction, resulting in successful removal of the tumour with negative margins. Medical and surgical management of pancreatic neuroendocrine tumours and PTHrP-mediated paraneoplastic hypercalcaemia is discussed.


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