A Membrane-Bound Form of the Acute-Phase Protein C-Reactive Protein Is the Galactose-Specific Particle Receptor on Rat Liver Macrophages

Pathobiology ◽  
1991 ◽  
Vol 59 (4) ◽  
pp. 272-275 ◽  
Author(s):  
Victoria Kolb-Bachofen
1956 ◽  
Vol 10 ◽  
pp. 151-152 ◽  
Author(s):  
Inger Brattsten ◽  
Per Hedlund ◽  
Bjørn Andersen ◽  
Einar Stenhagen ◽  
B. Thorell

2009 ◽  
Vol 36 (11) ◽  
pp. 2487-2490 ◽  
Author(s):  
MARJA PERTOVAARA ◽  
JUULIA JYLHÄVÄ ◽  
HANNU UUSITALO ◽  
JUHANI PUKANDER ◽  
HEIKKI HELIN ◽  
...  

Objective.Primary Sjögren’s syndrome (pSS) is an autoimmune disease in which the concentration of the acute-phase protein serum C-reactive protein (CRP) is low. We investigated whether levels of another acute-phase protein, serum amyloid A (SAA), are increased in patients with pSS and whether the immunological markers in patients with pSS are associated with variation in SAA levels.Methods.Serum SAA concentrations were measured by ELISA in 74 patients with pSS and in 56 control subjects with sicca symptoms.Results.Median SAA levels did not differ significantly between patients with pSS and subjects with sicca symptoms. In patients with pSS SAA concentrations correlated significantly with age, leukocyte count, CRP, interleukin 6, and C4. Unlike CRP, there was a significant inverse correlation between SAA and serum IgG levels and anti-SSA antibody titers, as well as a trend towards an inverse correlation between SAA and antinuclear antibody and rheumatoid factor titers.Conclusion.Our data imply that high SAA production could constitute a protective element in pSS: high SAA levels inhibit in particular various signs of B cell hyperreactivity, i.e., IgG and autoantibody production.


1943 ◽  
Vol 77 (2) ◽  
pp. 97-110 ◽  
Author(s):  
Ely Perlman ◽  
Jesse G. M. Bullowa ◽  
Ruth Goodkind

1. Studies of the precipitation reaction of C polysaccharide with C protein, and of C polysaccharide with C antibody are reported. The similarity between these two systems in this respect is demonstrated. 2. The differences between C protein and C antibody are emphasized. The differences between this protein and antibodies in general have been reported previously by others. 3. Electrophoretic studies show that C antibody is in the gamma globulin fraction of serum whereas C protein migrates with the alpha1 globulin fraction of acute phase protein.


The Analyst ◽  
2021 ◽  
Author(s):  
Fan Cai ◽  
Jun Wang ◽  
Yao Lin ◽  
Dianping Tang

C-reactive protein (CRP; an acute-phase protein) in patients with initial acute cerebral infarction neurological rehabilitation prediction has a significant correlation. Herein, a simple and sensitive anodic-stripping voltammetric (ASV) immunosensing system...


2004 ◽  
Vol 10 (3) ◽  
pp. 163-174 ◽  
Author(s):  
Patricia M.L. Ng ◽  
Zhenxiao Jin ◽  
Sandra S.H. Tan ◽  
Bow Ho ◽  
Jeak L. Ding

1953 ◽  
Vol 98 (4) ◽  
pp. 321-329 ◽  
Author(s):  
Harrison F. Wood

The ability of an adjuvant and its individual constituents to induce the production of Cx-reactive protein in rabbits has been studied. It was found that the adjuvant stimulated rabbits to produce large amounts of the acute phase protein for 3 to 6 days. Melted aquaphor blended with saline stimulated the production of Cx-reactive protein for 3 or 4 days. Mineral oil was less effective in stimulating the production of the protein than either adjuvant or aquaphor. Heat-killed Jamaica strain tubercle bacilli suspended in mineral oil did not induce the Cx-protein response. The ability of subcutaneously administered adjuvant without antigen incorporated in the saline phase to potentiate the antibody response of rabbits to the intravenously administered antigens, C-reactive protein and human gamma globulin, was investigated. It was found that the adjuvant-treated animals produced more precipitating antibody to the two intravenously administered antigens than did the control animals given intravenous antigen alone.


Sign in / Sign up

Export Citation Format

Share Document