Low-Dose Heparin in Gynecologic Surgery: Effect on Blood Coagulation Tests

1981 ◽  
Vol 10 (2) ◽  
pp. 97-103
Author(s):  
G. Levesque ◽  
M. Samama ◽  
A. Kher ◽  
P. Barbier ◽  
M.M. Horellou ◽  
...  
1982 ◽  
Vol 27 (2) ◽  
pp. 211-219 ◽  
Author(s):  
E.M. Pogliani ◽  
A. Vigo ◽  
E. Cofrancesco ◽  
M. Colombi ◽  
G. Cristoforetti ◽  
...  

1979 ◽  
Vol 41 (02) ◽  
pp. 337-345 ◽  
Author(s):  
Per Olov Hedlund ◽  
Margareta Blombäck

SummaryHeparin was administered subcutaneously 5.000 IU twice daily using a double blind method to ten of twenty-one patients undergoing transvesical prostatectomy.Platelet count, APTT, thrombin time, Reptilase time, Normotest, fibrinogen, Factor- VIII, ethanol gelation test, antithrombin III, fibrinolytic degradation products, α1-antitrypsin and α2-macroglobulin were studied pre- and postoperatively up to the 10th postoperative day. Statistical analysis of parameters of blood coagulation and fibrinolysis showed no significant difference between the two groups. The mechanism by which low dose heparin exerts its thromboprophylactic effect could not be elucidated from the study of the investigated parameters. The laboratory data gave no indication to a possible increased risk of postoperative hemorrhage.


1976 ◽  
Vol 36 (01) ◽  
pp. 157-164 ◽  
Author(s):  
P. M Mannucci ◽  
Luisa E. Citterio ◽  
N Panajotopoulos

SummaryThe effect of subcutaneous low-dose heparin on postoperative deep-vein thrombosis (D. V. T.) (diagnosed by the 125I-labelled fibrinogen test) has been investigated in a trial of 143 patients undergoing the operation of total hip replacement. Two randomized studies were carried out: in one the scanning for D.V.T. was carried out daily for 7 days post operatively and in the other for 15 days. In both, the incidence of D.V.T. was significantly lower in the heparin-treated patients (P<0.005). Bilateral D.V.T. was also prevented (P<0.05), through the extension of D.V.T. to the distal veins of the thigh was not significantly reduced. Heparin treatment was, however, followed by a higher incidence of severe postoperative bleeding (P< 0.02) and wound haematoma formation (P< 0.005), and the postoperative haemoglobin was significantly lower than in the control group (P<0.005). A higher number of transfused blood units was also needed by the heparin treated patients (P<0.001).


1982 ◽  
Vol 47 (03) ◽  
pp. 296-296
Author(s):  
Gordon Lowe ◽  
Jill Belch ◽  
Karen Regan ◽  
Charles Forbes ◽  
Colin Prentice

Circulation ◽  
1996 ◽  
Vol 94 (11) ◽  
pp. 2703-2707 ◽  
Author(s):  
P.M. Piatti ◽  
L.D. Monti ◽  
G. Valsecchi ◽  
M. Conti ◽  
R. Nasser ◽  
...  

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