Estimating Peak Work Rate during Incremental Cycle Ergometry from the 6-Minute Walk Distance: Differences between Reference Equations

BACKGROUND: The six-minute walk test (6MWT), a simple, reliable and valid test that uses the distance walked in six minutes (six-minute walk distance, 6MWD) to quantify functional exercise capacity, is widely used in chronic cardiopulmonary and non-cardiopulmonary disorders. However, th absence of reference standards for Nigerian school-aged children limits its utility in this age group OBJECTIVES: To develop normative values and equations for the 6MWT of school-aged Nigerian children METHODS: In a cross-sectional study, healthy Nigerian children aged 6-11 years in Lagos completed 6MWT on 20-meter straight outdoor courses in their schools following standardized guidelines. Potential predictors: demographic (age, sex), anthropometric (height, weight, chest circumference, leg length) and physiological data [pre-walk, immediate post-walk and 5th-minute post-walk heart rate (HR), oxygen saturation (SpO2), systolic blood pressure (SBP), diastolic blood pressure (DBP) and rating of perceived exertion (RPE)] and the difference between pre-walk and post-walk HR (HR change), SpO2 (SpO2 change), SBP (SBP change), DBP (DBP change) and RPE (RPE change). Primary outcomes:six-minute walk distance (6MWD) in meters. RESULTS: Overall, 627 pupils (52.1% girls) walked 504.6 (66.6) m (95% CI: 499.4, 509.8), ranging from 326.6 to 673.0 m; boys walking 16 m longer (p=0.002). Stepwise linear regression yielded 6MWD=347.9+14(Age in years)+1.6(HR change)+17.6(sex; male=1, female=0)+1.2(SBP change);R square=0.25.Previously published reference equations mostly over-estimated Nigerian children's 6MWD. CONCLUSION: The reference values and equations, after validation in other Nigerian geographic populations, may be useful for the functional evaluation of Nigerian children aged 6-11 years with chronic childhood disorders.

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Six-minute walk distance in healthy Singaporean adults cannot be predicted using reference equations derived from Caucasian populations

Respirology ◽

10.1111/j.1440-1843.2006.00820.x ◽

2006 ◽

Vol 11 (2) ◽

pp. 211-216 ◽

Cited By ~ 65

Author(s):

Hermione POH ◽

Peter R. EASTWOOD ◽

Nola M. CECINS ◽

Kheng Thye HO ◽

Sue C. JENKINS

Keyword(s):

Walk Distance ◽

Reference Equations ◽

Minute Walk Distance ◽

Minute Walk

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Reference equations for the 6-minute walk distance in healthy Portuguese subjects 18–70 years old

Pulmonology ◽

10.1016/j.pulmoe.2018.04.003 ◽

2019 ◽

Vol 25 (2) ◽

pp. 83-89 ◽

Cited By ~ 4

Author(s):

M.J. Oliveira ◽

R. Marçôa ◽

J. Moutinho ◽

P. Oliveira ◽

I. Ladeira ◽

...

Keyword(s):

Walk Distance ◽

Reference Equations ◽

Minute Walk Distance ◽

Minute Walk

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Inaccuracy of Estimating Peak Work Rate from Six-Minute Walk Distance in Patients with COPD

COPD Journal of Chronic Obstructive Pulmonary Disease ◽

10.3109/15412555.2012.655866 ◽

2012 ◽

Vol 9 (3) ◽

pp. 281-288 ◽

Cited By ~ 9

Author(s):

Maurice J.H. Sillen ◽

Jan H. Vercoulen ◽

Alex J. van‘t Hul ◽

Peter H.C. Klijn ◽

Emiel F.M. Wouters ◽

...

Keyword(s):

Work Rate ◽

Walk Distance ◽

Minute Walk Distance ◽

Minute Walk

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Reference values and regression equations for predicting the 6-minute walk distance in Saudi adults aged 50–80 years: A cross- sectional study

Journal of Back and Musculoskeletal Rehabilitation ◽

10.3233/bmr-200240 ◽

2021 ◽

pp. 1-11

Author(s):

Nawal S. AL-Ghamdi ◽

Afaf A.M. Shaheen

Keyword(s):

Physical Activity ◽

Reference Values ◽

Cross Sectional Study ◽

Regression Equations ◽

Sectional Study ◽

Walk Distance ◽

Cross Sectional ◽

Reference Equations ◽

Minute Walk Distance ◽

Minute Walk

BACKGROUND: The 6-minute walk test (6-MWT) is commonly used to measure functional capacity in clinical and research settings. The reference equations for predicting the 6-minute walk distance (6-MWD) in different populations have been established; however, there is a lack of information regarding healthy Saudi individuals over 50 years old. OBJECTIVES: This study aimed to establish the reference values of 6-MWD in a sample of healthy Saudi adults aged 50–80 years, develop regression equations for the established 6-MWD, and compare the measured 6-MWD in the present study with the predicted 6-MWD derived from the previously published regression equations. METHODS: In total, 210 healthy Saudi volunteers aged 50–80 years participated in this cross-sectional study. The 6-MWT was performed according to the American Thoracic Society (ATS) guidelines. Lung function, physical activity, blood pressure, heart rate, oxygen saturation, exertion level of leg fatigue, and sensation of dyspnea were measured. RESULTS: The mean 6-MWD was 396.2 ± 69.4 m. It was significantly correlated with age, sex, height, body mass index (BMI), and physical activity. The predictors of 6-MWD were age and BMI for men, while they were age, BMI, and height for women. They accounted for 25% and 35% of the total variance of 6-MWD for men and women, respectively. The measured 6-MWD was significantly shorter than the predicted 6-MWD. CONCLUSION: Saudi populations have significantly shorter 6-MWDs than those reported in other ethnic groups. The sex-specific equations developed in this study are expected to provide a useful measure of 6-MWT for Saudi adults. However, further investigation is required to validate the application of these equations to individuals living in different regions of Saudi Arabia.

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