Antimicrobial Peptides as a Major Part of the Innate Immune Defense at the Ocular Surface

Author(s):  
Fabian Garreis ◽  
Maria Gottschalt ◽  
Friedrich P. Paulsen
2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Jaquelina Julia Guzmán-Rodríguez ◽  
Alejandra Ochoa-Zarzosa ◽  
Rodolfo López-Gómez ◽  
Joel E. López-Meza

Antimicrobial peptides (AMPs) are part of the innate immune defense mechanism of many organisms and are promising candidates to treat infections caused by pathogenic bacteria to animals and humans. AMPs also display anticancer activities because of their ability to inactivate a wide range of cancer cells. Cancer remains a cause of high morbidity and mortality worldwide. Therefore, the development of methods for its control is desirable. Attractive alternatives include plant AMP thionins, defensins, and cyclotides, which have anticancer activities. Here, we provide an overview of plant AMPs anticancer activities, with an emphasis on their mode of action, their selectivity, and their efficacy.


2010 ◽  
Vol 134 (1) ◽  
pp. 59-73 ◽  
Author(s):  
Fabian Garreis ◽  
Thomas Schlorf ◽  
Dieter Worlitzsch ◽  
Philipp Steven ◽  
Lars Bräuer ◽  
...  

2004 ◽  
Vol 50 (3) ◽  
pp. 343-348 ◽  
Author(s):  
Robert A. Dorschner ◽  
Belen Lopez-Garcia ◽  
Jennifer Massie ◽  
Choll Kim ◽  
Richard L. Gallo

2020 ◽  
Vol 104 ◽  
pp. 506-516
Author(s):  
Jingguang Wei ◽  
Chen Li ◽  
Jisheng Ou ◽  
Xin Zhang ◽  
Zetian Liu ◽  
...  

2017 ◽  
Vol 70 ◽  
pp. 13-24 ◽  
Author(s):  
Liang Lu ◽  
Xu Wang ◽  
Sizhong Wu ◽  
Xuejiao Song ◽  
Ziqi Zou ◽  
...  

2016 ◽  
Vol 230 (2) ◽  
pp. 297-302 ◽  
Author(s):  
Martin N. Møller ◽  
Svend Kirkeby ◽  
Per Cayé-Thomasen

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