scholarly journals The Syndrome of Inappropriate Antidiuresis: Pathophysiology, Clinical Management and New Therapeutic Options

2011 ◽  
Vol 119 (1) ◽  
pp. c62-c73 ◽  
Author(s):  
Pasquale Esposito ◽  
Giovanni Piotti ◽  
Stefania Bianzina ◽  
Yehuda Malul ◽  
Antonio Dal Canton
Keyword(s):  
Clinical Management ◽  
Therapeutic Options ◽  
Inappropriate Antidiuresis

scholarly journals Updated Approaches against SARS-CoV-2

2020 ◽  
Vol 64 (6) ◽  
Author(s):  
Haiou Li ◽  
Yunjiao Zhou ◽  
Meng Zhang ◽  
Haizhou Wang ◽  
Qiu Zhao ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Management ◽  
Management Strategies ◽  
Therapeutic Options ◽  
Preclinical Models ◽  
Adequate Evidence

ABSTRACT Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in virology, epidemiology, and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing to develop a treatment for COVID-19. Recent studies have revealed many attractive therapeutic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.

Desmoplastic Small Round Cell Tumors: A review with focus on clinical management and therapeutic options

2021 ◽  
Vol 93 ◽  
pp. 102140
Author(s):  
Anne Hendricks ◽  
Kevin Boerner ◽  
Christoph-Thomas Germer ◽  
Armin Wiegering
Keyword(s):  
Clinical Management ◽  
Therapeutic Options ◽  
Round Cell ◽  
Small Round Cell ◽  
Round Cell Tumors

Malignant Biliary Obstruction

2018 ◽  
pp. 452-460
Author(s):  
Vibhor Wadhwa ◽  
Robert Liddell ◽  
Kelvin Hong
Keyword(s):  
Clinical Management ◽  
Biliary Obstruction ◽  
Malignant Biliary Obstruction ◽  
Accurate Diagnosis ◽  
Therapeutic Options ◽  
Direct Visualization ◽  
Diagnostic Strategies ◽  
Endoscopic Techniques ◽  
Non Invasive ◽  
Late Stages

Malignant causes of biliary obstruction are often difficult to treat, as these cancers frequently present at late stages. Fortunately, there are now many diagnostic and therapeutic interventional and endoscopic techniques used to facilitate accurate diagnosis and treatment. Diagnostic strategies range from non-invasive imaging to endoscopic fluoroscopy and ultrasound to facilitate biopsy, as well as direct visualization through cholangioscopy. Therapeutic options include biliary stricture dilation, stenting, and drainage both for symptomatic/palliative management and to optimize patients for further medical and surgical management. Management of these patients are best served by a multidisciplinary approach. This chapter will review the currently available techniques for diagnosing and treating malignant biliary obstruction as well as the issues related to clinical management of these complicated patients.

Assessing the Use of Age-Equivalent Scores in Clinical Management

1992 ◽  
Vol 23 (1) ◽  
pp. 6-8 ◽  
Author(s):  
Carol W. Lawrence
Keyword(s):  
Case Management ◽  
Clinical Management ◽  
Management Decisions ◽  
Language Deficits

Speech-language evaluation reports from many institutions present age-equivalent scores as the evidence for speech-language deficits. Yet, the value and interpretation of this measurement criterion requires clinical scrutiny. This article reviews the concept and derivation of age-equivalent scores and presents arguments against their use in case management decisions.

Structural Aspects of Phonological Development

1988 ◽  
Vol 19 (1) ◽  
pp. 5-16 ◽  
Author(s):  
Karen E. Pollock ◽  
Richard G. Schwartz
Keyword(s):  
Clinical Management ◽  
Structural Complexity ◽  
Strong Preference ◽  
Phonological Development ◽  
Structural Position ◽  
Phonological Disorders ◽  
Syllabic Structure ◽  
The Relationship ◽  
Structural Aspects ◽  
Target Words

The relationship between syllabic structure and segmental development was examined longitudinally in a child with a severe phonological disorder. Six speech samples were collected over a 4-year period (3:5 to 7:3). Analyses revealed gradual increases in the complexity and diversity of the syllable structures produced, and positional preferences for sounds within these forms. With a strong preference for [d] and [n] at the beginning of syllables, other consonants appeared first at the end of syllables. Implications for clinical management of phonological disorders include the need to consider both structural position and structural complexity in assessing segmental skills and in choosing target words for intervention.

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