scholarly journals Opioid-induced constipation: a narrative review of therapeutic options in clinical management

2019 ◽  
Vol 32 (2) ◽  
pp. 69-78 ◽  
Author(s):  
Kordula Lang-Illievich ◽  
Helmar Bornemann-Cimenti
2011 ◽  
Vol 119 (1) ◽  
pp. c62-c73 ◽  
Author(s):  
Pasquale Esposito ◽  
Giovanni Piotti ◽  
Stefania Bianzina ◽  
Yehuda Malul ◽  
Antonio Dal Canton

2020 ◽  
Vol 64 (6) ◽  
Author(s):  
Haiou Li ◽  
Yunjiao Zhou ◽  
Meng Zhang ◽  
Haizhou Wang ◽  
Qiu Zhao ◽  
...  

ABSTRACT Novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lies behind the ongoing outbreak of coronavirus disease 2019 (COVID-19). There is a growing understanding of SARS-CoV-2 in virology, epidemiology, and clinical management strategies. However, no anti-SARS-CoV-2 drug or vaccine has been officially approved due to the absence of adequate evidence. Scientists are racing to develop a treatment for COVID-19. Recent studies have revealed many attractive therapeutic options, even if some of them remain to be further confirmed in rigorous preclinical models and clinical trials. In this minireview, we aim to summarize the updated potential approaches against SARS-CoV-2. We emphasize that further efforts are warranted to develop the safest and most effective approach.


2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
David Plevin ◽  
Nicholas Smith

Anxiety and depression in children and adolescents with epilepsy are common comorbidities which place a significant burden on patients and families and complicate the clinical management of epilepsy. This paper presents a narrative review on the aetiology, phenomenology, assessment, and management of depression and anxiety among paediatric patients with epilepsy. The recognition of affective comorbidity in paediatric epilepsy is limited at present, and the contributory role of antiepileptic medication towards such comorbidity must be considered by clinicians.


2020 ◽  
Vol 93 (1115) ◽  
pp. 20200465 ◽  
Author(s):  
Roberto Luigi Cazzato ◽  
Julien Garnon ◽  
Guillaume Koch ◽  
Danoob Dalili ◽  
Pramod Prabhakar Rao ◽  
...  

Management of musculoskeletal (MSK) tumours has traditionally been delivered by surgeons and medical oncologists. However, in recent years, image-guided interventional oncology (IO) has significantly impacted the clinical management of MSK tumours. With the rapid evolution of relevant technologies and the expanding range of clinical indications, it is likely that the impact of IO will significantly grow and further evolve in the near future. In this narrative review, we describe well-established and new interventional technologies that are currently integrating into the IO armamentarium available to radiologists to treat MSK tumours and illustrate new emerging IO indications for treatment.


2021 ◽  
Vol 10 (19) ◽  
pp. 4367
Author(s):  
Alejandro I. Lorenzo-Pouso ◽  
José Bagán ◽  
Leticia Bagán ◽  
Pilar Gándara-Vila ◽  
Cintia M. Chamorro-Petronacci ◽  
...  

Background: Nearly two decades have passed since a paradoxical reaction in the orofacial region to some bone modifying agents and other drugs was recognized, namely medication-related osteonecrosis of the jaw (MRONJ). Purpose: The aim of this manuscript was to critically review published data on MRONJ to provide an update on key terminology, concepts, and current trends in terms of prevention and diagnosis. In addition, our objective was to examine and evaluate the therapeutic options available for MRONJ. Methods: The authors perused the most relevant literature relating to MRONJ through a search in textbooks and published articles included in several databases for the years 2003–2021. Results and conclusions: A comprehensive update of the current understanding of these matters was elaborated, addressing these topics and identifying relevant gaps of knowledge. This review describes our updated view of the previous thematic blocks, highlights our current clinical directions, and emphasizes controversial aspects and barriers that may lead to extending the accumulating body of evidence related to this severe treatment sequela.


2020 ◽  
Vol 51 (1) ◽  
pp. 74-83 ◽  
Author(s):  
Erin M. Picou ◽  
Hilary Davis ◽  
Anne Marie Tharpe

Purpose Current recommendations for clinical management of school-aged children with limited useable hearing unilaterally primarily focus on remote microphone systems and preferential seating. The purpose of this narrative review is to examine the existing evidence supporting these recommendations. Method A narrative review was conducted, focused on nonsurgical interventions for children with limited useable hearing unilaterally. Results Six articles were identified. Three survey studies suggest high use rates and improved academic performance with contralateral routing of signal systems. One laboratory study suggests students with hearing loss need to sit closer to the desired signal (e.g., teacher) than their peers with normal hearing to achieve similar speech recognition. Two laboratory studies suggest remote microphone systems provide consistent benefits when the microphone is located near the talker of interest, whereas contralateral routing of signal systems impairs performance in noise. Conclusions The discrepancy between survey studies and laboratory studies could be explained partly due to the difference between listening situations in the laboratory and in classrooms. Everyone in the classroom is a potential talker of interest, and the listening environments are often dynamic. Thus, contralateral routing of signal systems might have more potential to improve classroom communication than was suggested by the laboratory studies. Recommendations for microphone technologies should be based on the extent to which a student is struggling, where the student sits in the classroom, and where the important talkers are located. There is not one optimal recommendation for all students, but a combination of remote microphone and contralateral routing of signal systems could work for most students. Supplemental Material https://doi.org/10.23641/asha.9956663


Author(s):  
Maria Scudo ◽  
Luciano Petruzziello ◽  
Fabiana Carbone ◽  
Alessandra Logoteta ◽  
Giulia Paoni Saccone ◽  
...  

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