scholarly journals OPG/RANK/RANKL Axis in Stabilization of Spontaneously Restored Sinus Rhythm in Permanent Atrial Fibrillation Patients after Mitral Valve Surgery

Cardiology ◽  
2013 ◽  
Vol 124 (1) ◽  
pp. 18-24 ◽  
Author(s):  
Lei Xi ◽  
Hailong Cao ◽  
Jinfu Zhu ◽  
Oluf Dimitri Røe ◽  
Mingna Li ◽  
...  
2015 ◽  
Vol 31 (4) ◽  
pp. 593-598 ◽  
Author(s):  
Carlo Rostagno ◽  
Sandro Gelsomino ◽  
Irene Capecchi ◽  
Alessandra Rossi ◽  
Gian Franco Montesi ◽  
...  

2004 ◽  
Vol 19 (5) ◽  
pp. 376-382 ◽  
Author(s):  
Fernando Hornero ◽  
Ignacio Rodriguez ◽  
Jose Buendia ◽  
Maria Bueno ◽  
Maria J. Dalmau ◽  
...  

2009 ◽  
Vol 64 (6) ◽  
pp. 767-770 ◽  
Author(s):  
Y.-X. Zhou ◽  
B. Leobon ◽  
D. Roux ◽  
Y. Glock ◽  
Y.-Q. Mei ◽  
...  

2018 ◽  
Vol 2 (Issue 4) ◽  
pp. 106
Author(s):  
Leonardo Canale ◽  
Bruno Azevedo ◽  
Marcelo Goulart Correia ◽  
Ernesto Chavez ◽  
Erica Macedo ◽  
...  

Objective: To evaluate the presence of sinus rhythm or atrial fibrillation (AF) in patients who had mitral valve surgery with concomitant surgical ablation of AF, by unipolar or bipolar radiofrequency. Methods: Adults patients who had mitral valve replacement or mitral valvuloplasty with concomitant surgical ablation of AF, either by unipolar or bipolar radiofrequency, were consecutively included between the 2008 and 2012. Surgery was done by conventional median sternotomy. Results: A total of 99 patients were included; 20 (20.2%) had surgical ablation by unipolar energy and 79 (79.8%) by bipolar energy. There were 76 (76.8%) women, and mean age± SD was 51 ±11 years.  The median duration of AF before surgery was 41 months. Type of AF was paroxysmal in 21 (21%), persistent in 11 (11%), and long-standing persistent in 67 (67%). Mean left atrium size in the preoperative period was 5.54 ± 0.82 cm. Mean left ventricular ejection fraction was 58±12.4%. Types of mitral valve surgery were valvuloplasty (n=10), mechanical valve replacement in 30, and bioprosthesis replacement in 59. Concomitant tricuspid annuloplasty was performed in 39 patients. Thirty- day mortality was 8/99 (8%). Mean follow-up time was 1274 days (3.49 years). Survival was 92%. After 4 years no patient who had had unipolar ablation was in sinus rhythm, whilst 67% of those who had bipolar energy ablation were in sinus rhythm (p<0.001). Conclusion: The use of bipolar energy is superior to unipolar energy in the surgical ablation of atrial fibrillation in patients submitted to mitral valve surgery.


QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M T Elsayegh ◽  
M A Elghannam ◽  
A M Ammar ◽  
A S Taha ◽  
A B Elkerdany

Abstract Background Ablation devices are being utilized in surgical procedures treating atrial fibrillation. Few studies seek to define a cut-off value for left atrial diameter size beyond which risks of procedure outweigh chance of sinus recovery. This study aims to identify a cut-off value for pre-operative left atrial diameter to assess the efficacy of surgical radio-frequency ablation for treatment of chronic atrial fibrillation in patients undergoing mitral valve surgery. Methods A prospective 6-month follow-up cohort study was done, in which 40 patients were recruited during the period from May 2016 till April 2018. All patients had rheumatic mitral valve disease and permanent atrial fibrillation. Receiver operator characteristic (ROC) curves were used to calculate the area under the curve and cut-off value for left atrial diameter. The efficacy of the overall survival time was estimated using the Kaplan-Meier method. Results Pre-operatively left atrial diameter of > 59 mm was significantly associated with decrease in the possibility of reverting to sinus rhythm after surgery (OR 0.292, p-value = 0.001). The cut-off value for left atrial diameter was 59mm (sensitivity = 93.3%, specificity = 96.1%). Kaplan-Meier survival estimates were 175.07 days (156.3 - 193.9) for patients with left atrial diameter < 59mm and 62.64 days (26.6-98.7) for patients with left atrial diameter > 59mm. Conclusion In patients undergoing mitral valve surgery, higher degrees of ablation success are associated with smaller left atrial diameter in terms of conservation of the sinus rhythm post operatively.


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