Effect of Hemodilution with Dextran, Stroma-Free Hemoglobin Solution and Fluosol-DA on Experimental Myocardial Ischemia in the Dog

2015 ◽  
pp. 54-69 ◽  
Author(s):  
G. P. Biro
Keyword(s):  
Myocardial Ischemia ◽  
Free Hemoglobin ◽  
Hemoglobin Solution ◽  
Experimental Myocardial Ischemia

scholarly journals EVALUATION OF A STROMA-FREE HEMOGLOBIN SOLUTION FOR USE AS A PLASMA EXPANDER

1967 ◽  
Vol 126 (6) ◽  
pp. 1127-1142 ◽  
Author(s):  
S. Frederick Rabiner ◽  
J. Raymond Helbert ◽  
Harry Lopas ◽  
Lila H. Friedman
Keyword(s):  
Carrying Capacity ◽  
Vital Signs ◽  
Free Hemoglobin ◽  
Hemoglobin Solution ◽  
Plasma Expander ◽  
Chronic Effects ◽  
Coagulant Activity ◽  
Methemoglobin Formation ◽  
Oxygen Carrying Capacity ◽  
Acute And Chronic Effects

The preparation of large quantities of a stable, stroma-free hemoglobin solution without coagulant activity is described. Following infusion of this solution into phlebotomized dogs, there is no methemoglobin formation, no adverse effects on vital signs, and no demonstrable activation of blood coagulation. The hemoglobin maintains its oxygen-carrying capacity and liberates oxygen into tissues. Acute and chronic effects on renal function following infusion of this preparation were also studied and no effect on clearance of urea, creatinine, or P.A.H. could be demonstrated. There was no change in urinary output and histological sections revealed no lesions attributable to hemoglobin toxicity. It is concluded that a stroma-free hemoglobin solution may have use as a plasma expander.

Annexin 1 peptides protect against experimental myocardial ischemia‐reperfusion: analysis of their mechanism of action

2001 ◽  
Vol 15 (12) ◽  
pp. 2247-2256 ◽  
Author(s):  
Mylinh La ◽  
Michele D'Amico ◽  
Silvio Bandiera ◽  
Clara Di Filippo ◽  
Sonia M. Oliani ◽  
...  
Keyword(s):  
Myocardial Ischemia ◽  
Mechanism Of Action ◽  
Ischemia Reperfusion ◽  
Annexin 1 ◽  
Myocardial Ischemia Reperfusion ◽  
Experimental Myocardial Ischemia

Cardioprotection with 8-O-acetyl shanzhiside methylester on experimental myocardial ischemia injury

2012 ◽  
Vol 47 (1) ◽  
pp. 124-130 ◽  
Author(s):  
Ze-Chun Kang ◽  
Wang-Lin Jiang ◽  
Yong Xu ◽  
Hai-Bo Zhu ◽  
Jian Hou
Keyword(s):  
Myocardial Ischemia ◽  
Experimental Myocardial Ischemia

Tactoid formation in deer hemoglobin

1960 ◽  
Vol 199 (1) ◽  
pp. 190-192 ◽  
Author(s):  
John H. Moon
Keyword(s):  
Odocoileus Virginianus ◽  
Sickle Cell ◽  
Moving Boundary ◽  
Paper Electrophoresis ◽  
Free Hemoglobin ◽  
Hemoglobin Solution ◽  
Hunting Season ◽  
Phase Microscopy ◽  
Veronal Buffer ◽  
Kinetics Of

Sickle cell preparations were made on eight Virginia white-tail deer ( Odocoileus virginianus) killed during the 1958–59 hunting season. All preparations showed sickling. Paper electrophoresis of carboxyhemoglobin from these animals revealed identical mobilities and a single hemoglobin component present at pH 8.6. Alkali denaturation of the deer carboxyhemoglobin solution showed that it was markedly resistant to alkali denaturation and that the kinetics of the denaturation were different from that of human cord hemoglobin. Deer carboxyhemoglobin migrated 0.6 x 10–5 cm2/volt/sec.–1 faster than human carboxyhemoglobin A in moving boundary electrophoresis in veronal buffer at pH 8.2. Tactoids were demonstrated in free hemoglobin solution with phase microscopy after concentration of the solution. These particles are very similar morphologically to these prepared from hemoglobin solution containing hemoglobin S.

scholarly journals The Effect of Mofettes on Oxidative Stress/Antioxidant Balance in Experimental Myocardial Ischemia

In Vivo ◽  
2019 ◽  
Vol 33 (6) ◽  
pp. 1911-1920
Author(s):  
GABRIELA DOGARU ◽  
ADRIANA BULBOACA ◽  
PAUL MIHAI BOARESCU ◽  
LORENA CIUMARNEAN ◽  
VASILE RUS ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Myocardial Ischemia ◽  
Experimental Myocardial Ischemia
Sign in / Sign up

Export Citation Format

Share Document