scholarly journals Contrast-Induced Nephropathy Is Less Common in Patients with Good Coronary Collateral Circulation

2017 ◽  
Vol 7 (4) ◽  
pp. 316-323 ◽  
Author(s):  
Eyup Avci ◽  
Tarik Yildirim ◽  
Hasan Kadi
Keyword(s):  
Collateral Circulation ◽  
Independent Predictor ◽  
Inclusion Criteria ◽  
Contrast Induced Nephropathy ◽  
Coronary Collateral Circulation ◽  
Coronary Collateral ◽  
Major Coronary Artery ◽  
Study Population ◽  
Blood Creatinine

Background/Aims: Contrast-induced nephropathy (CIN) is a typically reversible type of acute renal failure that develops after exposure to contrast agents; underlying endothelial dysfunction is thought to be an important risk factor for CIN. Although the mechanism of coronary collateral circulation (CCC) is not fully understood, a pivotal role of the endothelium has been reported in many studies. The aim of this study was to investigate whether there is a relationship between CCC and CIN. Methods: Patients with at least one occluded major coronary artery and blood creatinine analyses performed before and on the second day after angiography were included in the study. CIN was defined as a 25% or greater elevation of creatinine on the second day after exposure to the contrast agent. Collateral grading was performed according to the Rentrop classification. Patients were grouped according to whether they developed CIN or not, i.e., CIN(-) and CIN(+) group. Results: A total of 214 patients who met the inclusion criteria were included in the study. CIN was diagnosed in 43 patients (20.1%) in the study population. Good CCC was identified in 112 patients (65.5%) in the CIN(-) group, whereas it was identified in 13 patients (30.2%) in the CIN(+) group. In the CIN(-) group, good CCC was significantly more frequent (p < 0.001). Furthermore, collateral circulation was an independent predictor of CIN. Conclusion: Good collateral circulation was associated with a lower frequency of CIN, and poor collateral circulation was an independent predictor of CIN.

Role of the Coronary Collateral Circulation in the Preservation of Left Ventricular Function

Radiology ◽  
1975 ◽  
Vol 114 (2) ◽  
pp. 305-313 ◽  
Author(s):  
Harvey S. Hecht ◽  
Julian M. Aroesty ◽  
Eugene Morkin ◽  
Paul J. LaRaia ◽  
Sven Paulin
Keyword(s):  
Left Ventricular Function ◽  
Ventricular Function ◽  
Collateral Circulation ◽  
Left Ventricular ◽  
Coronary Collateral Circulation ◽  
Coronary Collateral

The impact of the coronary collateral circulation on outcomes in patients with acute coronary syndromes: results from the ACUITY trial

Heart ◽  
2013 ◽  
Vol 100 (8) ◽  
pp. 647-651 ◽  
Author(s):  
Pascal Meier ◽  
Alexandra J Lansky ◽  
Martin Fahy ◽  
Ke Xu ◽  
Harvey D White ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Collateral Circulation ◽  
Major Adverse Cardiac Events ◽  
Cardiac Events ◽  
Coronary Collateral Circulation ◽  
Coronary Syndrome ◽  
Coronary Collateral ◽  
Adverse Cardiac Events ◽  
The Impact

ObjectiveWe sought to assess the prognostic role of collaterals in a large population of patients presenting with an acute coronary syndrome (ACS).MethodsThe coronary collateral circulation was assessed by an independent angiographic core laboratory using the Rentrop Score in patients enrolled in the randomised Acute Catheterization and Urgent Intervention Triage Strategy trial.ResultsThe cohort comprised 5412 patients with moderate to high risk ACS. A total of 858 patients (16.0%) had visible collaterals while 4554 patients (84.0%) had no collaterals. After multivariable adjustment, there were no differences in clinical outcomes at 1 year between the groups, including major adverse cardiac events (MACE) (HR 0.94 (95% CI 0.76 to 1.16), p=0.55), mortality (HR 1.03 (0.65 to 1.62), p=0.91), myocardial infarction (MI) (HR 1.07 (0.83 to 1.38), p=0.60) and unplanned target vessel revascularisation (TVR) (HR 0.95 (0.71 to 1.28), p=0.75). Similarly, in the subgroup of patients undergoing percutaneous coronary intervention (PCI), the adjusted HR for major adverse cardiac events was 1.1 (0.76 to 1.61), p=0.595; 0.81 (0.10 to 6.44), p=0.999 for mortality; and 0.86 (0.54 to 1.35), p=0.564 for MI. The risk of unplanned TVR was increased (HR 2.74 (1.48 to 5.10), p=0.004).ConclusionsIn contrast to other studies, this large core laboratory-based analysis does not confirm a beneficial role of visible coronary collateral vessels on clinical outcomes in patients with ACS; the presence of collaterals was even associated with increased mortality in the unadjusted analysis. Collaterals were associated with a higher risk of TVR in patients undergoing PCI, a finding that may not have been fully corrected given confounders and clinical differences between the groups.Trial registrationClinicalTrials.gov Identifier: NCT00093158.

Association of fibrinogen/albumin ratio and coronary collateral circulation in stable coronary artery disease patients

2020 ◽  
Vol 14 (16) ◽  
pp. 1513-1520
Author(s):  
Yipin Zhao ◽  
Shunli Wang ◽  
Jiaojiao Yang ◽  
Zebin Lin ◽  
Qingwei Chen
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Odds Ratio ◽  
Collateral Circulation ◽  
Independent Predictor ◽  
Stable Coronary Artery Disease ◽  
Coronary Collateral Circulation ◽  
Albumin Ratio ◽  
Coronary Collateral ◽  
Artery Disease

Aim: To investigate whether fibrinogen/albumin ratio (FAR) has an association with the coronary collateral circulation (CCC) in patients with stable coronary artery disease. Materials & methods: A total of 391 patients with stable coronary artery disease who underwent coronary angiography were included. The patients were divided into two groups according to the Rentrop score. Results: The poorly developed CCC group had a significantly higher FAR level compared with the well-developed CCC group (p < 0.001). In the multivariate analysis, the FAR (odds ratio: 1.700; 95% CI: 1.420–2.036; p < 0.001) was an independent predictor of poorly developed CCC. Conclusion: FAR can be used as one of the independent predictors of CCC formation.

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