scholarly journals Fully Automatic Speech-Based Analysis of the Semantic Verbal Fluency Task

2018 ◽  
Vol 45 (3-4) ◽  
pp. 198-209 ◽  
Author(s):  
Alexandra König ◽  
Nicklas Linz ◽  
Johannes Tröger ◽  
Maria Wolters ◽  
Jan Alexandersson ◽  
...  

Background: Semantic verbal fluency (SVF) tests are routinely used in screening for mild cognitive impairment (MCI). In this task, participants name as many items as possible of a semantic category under a time constraint. Clinicians measure task performance manually by summing the number of correct words and errors. More fine-grained variables add valuable information to clinical assessment, but are time-consuming. Therefore, the aim of this study is to investigate whether automatic analysis of the SVF could provide these as accurate as manual and thus, support qualitative screening of neurocognitive impairment. Methods: SVF data were collected from 95 older people with MCI (n = 47), Alzheimer’s or related dementias (ADRD; n = 24), and healthy controls (HC; n = 24). All data were annotated manually and automatically with clusters and switches. The obtained metrics were validated using a classifier to distinguish HC, MCI, and ADRD. Results: Automatically extracted clusters and switches were highly correlated (r = 0.9) with manually established values, and performed as well on the classification task separating HC from persons with ADRD (area under curve [AUC] = 0.939) and MCI (AUC = 0.758). Conclusion: The results show that it is possible to automate fine-grained analyses of SVF data for the assessment of cognitive decline.

2019 ◽  
Author(s):  
Nicklas Linz ◽  
Kristina Lundholm Fors ◽  
Hali Lindsay ◽  
Marie Eckerström ◽  
Jan Alexandersson ◽  
...  

2007 ◽  
Vol 1 (4) ◽  
pp. 381-385 ◽  
Author(s):  
Mariana Jardim Azambuja ◽  
Monica Santoro Haddad ◽  
Marcia Radanovic ◽  
Egberto Reis Barbosa ◽  
Letícia Lessa Mansur

Abstract Verbal fluency tasks have been identified as important indicators of executive functioning impairment in patients with frontal lobe dysfunction. Although the usual evaluation of this ability considers phonologic and semantic criteria, there is some evidence that fluency of verbs would be more sensitive in disclosing frontostriatal physiopathology since frontal regions primarily mediate retrieval of verbs. Huntington's disease usually affects these circuitries. Objective: To compare three types of verbal fluency task in the assessment of frontal-striatal dysfunction in HD subjects. Methods: We studied 26 Huntington's disease subjects, divided into two subgroups: mild (11) and moderate (15) along with 26 normal volunteers matched for age, gender and schooling, for three types of verbal fluency: phonologic fluency (F-A-S), semantic fluency and fluency of verbs. Results: Huntington's disease subjects showed a significant reduction in the number of words correctly generated in the three tasks when compared to the normal group. Both controls and Huntington's disease subjects showed a similar pattern of decreasing task performance with the greatest number of words being generated by semantic elicitation followed by verbs and lastly phonologic criteria. We did not find greater production of verbs compared with F-A-S and semantic conditions. Moreover, the fluency of verbs distinguished only the moderate group from controls. Conclusion: Our results indicated that phonologic and semantic fluency can be used to evaluate executive functioning, proving more sensitive than verb fluency. However, it is important to point out that the diverse presentations of Huntington's disease means that an extended sample is necessary for more consistent analysis of this issue.


2016 ◽  
Vol 74 (2) ◽  
pp. 69-77 ◽  
Author(s):  
Masahiro Takamura ◽  
Yasumasa Okamoto ◽  
Go Okada ◽  
Shigeru Toki ◽  
Tetsuya Yamamoto ◽  
...  

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Joe Nocera ◽  
Bruce Crosson ◽  
Kevin Mammino ◽  
Keith M. McGregor

Previous work has shown that older adults who evidence increased right inferior frontal gyrus (IFG) activity during language tasks show decreased sematic verbal fluency performance. The current study sought to evaluate if an aerobic exercise intervention can alter patterns of brain activity during a semantic verbal fluency task assessed by functional magnetic resonance imaging (fMRI). Thirty-two community-dwelling, sedentary older adults were enrolled to a 12-week aerobic “Spin” exercise group or a 12-week nonaerobic exercise control condition (Balance). Thirty participants completed their assigned intervention (16 Spin; 14 Balance) with pre- and postintervention assessments of a semantic verbal fluency task during fMRI and estimated VO2max testing. There was a significant increase in the change scores for estimated VO2max of the Spin group when compared to the Balance group. Semantic verbal fluency output within the scanner was also improved in the Spin group as compared to controls at postassessment. Group fMRI comparisons of IFG activity showed lower activity in the right IFG following the intervention in the aerobic Spin group when compared to the Balance group. Regression analysis of imaging data with change in both estimated VO2max and semantic verbal fluency was negatively correlated with activity in right IFG. The current work is registered as clinical trial with NCT01787292 and NCT02787655.


PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0217814 ◽  
Author(s):  
T. P. Taporoski ◽  
N. E. Duarte ◽  
S. Pompéia ◽  
A. Sterr ◽  
L. M. Gómez ◽  
...  

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