Autologous Non-Cultured Epidermal Cellular Grafting in the Surgical Treatment of Stable Vitiligo: The Skin Hospital Protocol

Dermatology ◽  
2021 ◽  
pp. 1-3
Author(s):  
Brent J. Doolan ◽  
Michelle Weaich ◽  
Joanne Mamo ◽  
Monisha Gupta
Keyword(s):  
Cost Effective ◽  
Outpatient Setting ◽  
Skin Grafts ◽  
Mixed Cell ◽  
Recipient Site ◽  
Mixed Cell Population ◽  
Petri Dishes ◽  
Research Facilities ◽  
Large Research ◽  
Hospital Protocol

Autologous non-cultured epidermal cellular grafting is the treatment of choice for patients with stable refractory vitiligo. Recently, studies have shown cost-effective alternatives for this procedure, superseding previous techniques that required large research facilities or expensive pre-packaged kits. We provide modifications to current techniques, including the use of individual Petri dishes to allow for processing larger skin grafts, hyfrecation instead of conventional manual dermabrasion of the recipient site to reduce scar formation as well as better margin delineation, and an intravenous giving set with a filter for improved filtration of the mixed cell population. These modifications facilitated sufficient skin repigmentation in a cost-effective outpatient setting.

A COMPARATIVE STUDY OF EFFICACY, POTENCY AND RECOVERY OF INTRATHECAL 0.5% ROPIVACAINE WITH FENTANYLAND 0.5% LEVOBUPIVACAINE WITH FENTANYL IN LOWER ABDOMINAL SURGERIES IN PATIENTS OF 18-60YEARS OF AGE

2021 ◽  
pp. 74-76
Author(s):  
Payel Mitra ◽  
Archana Roy ◽  
Aamir Huda
Keyword(s):  
Comparative Study ◽  
Motor Block ◽  
Length Of Hospital Stay ◽  
Cost Effective ◽  
Outpatient Setting ◽  
P Value ◽  
Equal Concentration ◽  
Medical College ◽  
Institutional Ethics ◽  
Care Surgery

INTRODUCTION:The recent trend in health care centres everywhere is to provide cost effective care to the patients. There is an increasing trend towards ambulatory day care surgery and rapid discharge of the patients. The operation of inguinal hernia or incisional hernia and even simple ligation surgeries are done without much complexities nowadays and can be completed in 60-90min without much intra or postoperative complications. Hence these have become an ideal procedure for outpatient setting and thereby reducing length of hospital stay. AIMS AND OBJECTIVE:A comparative study of efcacy, potency and recovery of intrathecal 0.5% ropivacaine with fentanyl and 0.5% levobupivacaine with fentanyl in lower abdominal surgeries in patients of 18-60years of age. MATERIALS AND METHOD: This is a prospective, comparative, observational study was conducted on 60 patients undergoing various lower abdominal surgeries under subarachnoid block (SAB) at Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal. This study was conducted over a period of 24-month. Approval of the Institutional Ethics Committee was taken. Awritten informed consent in the local language was taken from every patient. RESULT AND ANALYSIS: In RF 5 patients (17%) had onset at 3min, 17patients (57%) at 6min, 7 patients (23%) at 9min, 1 patient (3%) at 12min. In LBF 8 patients had onset at 0 min, 22 patients had onset at 3min. p value is less than 0.0001 which is statistically signicant. In RF, 23 patients (77%) had duration of motor block for 150min and 7 patients (23%) had for 180min. In LBF, 26 patients (87%) had duration of motor block for 210 min and 4 patients (13%) had for 180min. The p value is less than 0.0001, which is statistically signicant. SUMMARYAND CONCLUSION: This study was to compare potency, efcacy and recovery between the two groups of drugs. A potency of a drug is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity. Here both the drugs in comparison was given in equal concentration and found that levobupivacaine produced higher effect, reached Bromage 3 in lesser time than ropivacaine. So levobupivacaine was more potent drug. Efcacy is the ability to get a job done satisfactorily

scholarly journals Quantitation of mast cell heparin by flow cytofluorometry.

1976 ◽  
Vol 24 (12) ◽  
pp. 1231-1238 ◽  
Author(s):  
L Enerbäck ◽  
G Berlin ◽  
I Svensson ◽  
I Rundquist
Keyword(s):  
Mast Cell ◽  
Mast Cells ◽  
Mixed Cell ◽  
Flow Cytofluorometry ◽  
Frequency Distributions ◽  
Cell Counts ◽  
Mixed Cell Population ◽  
Number Of Cells ◽  
Excellent Reproducibility

Mast cells can be automatically identified in a mixed cell population by flow cytofluorometry after Berberine sulphate staining. Volume specific counts of the total number of cells and number of mast cells, as well as frequency distributions of fluorescence intensities of mast cells, based on a large number of cells, can be rapidly obtained. Results obtained by microscope fluorometry of cells identified by phase contrast microscopy showviously published results it may be inferred that the fluorescence intensity of individual mast cells is proportional to mast cell heparin content. The automated cell counts correlated very well with manual hemocytometer counts. Both cell counts and the determination of mean mast cell fluorescence showed excellent reproducibility.

Neutron Scattering in Materials Sciences

MRS Bulletin ◽  
1990 ◽  
Vol 15 (11) ◽  
pp. 37-40
Author(s):  
Simon C. Moss ◽  
Stephen M. Shapiro
Keyword(s):  
Neutron Scattering ◽  
Materials Science ◽  
Depth Profiling ◽  
Materials Testing ◽  
Magnetic Structures ◽  
Transmutation Doping ◽  
Radiation Induced ◽  
Scientists And Engineers ◽  
Research Facilities ◽  
Large Research

At the 1989 MRS Fall Meeting the present guest editors and J.D. Jorgensen chaired a symposium on “Neutron Scattering for Materials Science.” Approximately 80 papers were presented, covering a great variety of topics which joined members of the materials science and neutron scattering communities. Because of that symposium's success, it was decided to bring the topic of Neutron Scattering to the wider attention of the materials community through this special issue of the MRS BULLETIN.Our purpose is twofold. First, neutrons have increasingly come to play a crucial role, both here and especially in Europe, in our understanding of the structure and properties of materials. Through the manipulation of materials (radiation-induced effects, transmutation doping of semiconductors), nondestructive materials testing (residual stress measurements on industrial-sized objects, depth profiling of ion-implanted semiconductors) and structural and dynamical studies, academic, government, and industrial scientists and engineers are coming to recognize the broad utility of neutron methods. We would like to highlight some of the advances in this field for MRS BULLETIN readers.Second, neutron scattering presents an excellent example of the contribution of our large research facilities to the solution of both basic and applied problems in materials science. Without the major neutron scattering centers we would be severely limited in the scope of our materials activities (no knowledge of magnetic structures and only primitive insight into polymer structures, for example).

scholarly journals Continuation of Indoor Prescribed Antibiotics in the Outpatient Treatment of Neonatal Sepsis

2017 ◽  
Vol 42 (3) ◽  
pp. 137-141
Author(s):  
SM Rafiqul Islam ◽  
Khurshid Talukder ◽  
Monira Akter
Keyword(s):  
Neonatal Sepsis ◽  
Cost Effective ◽  
Early Discharge ◽  
Outpatient Setting ◽  
Suspected Sepsis ◽  
Group Data ◽  
Effective Option ◽  
Long Time ◽  
Initial Improvement ◽  
Time Of Admission

Neonatal sepsis is a common problem whose antibiotic treatment is usually recommended whilst admitted in hospital for at least 10-14 days. Families in Bangladesh however are reluctant to stay in hospital to complete the treatment for such a long time due to reasons such as financial difficulties and either or both are working parents. This leads to incomplete treatment of neonatal sepsis. We hypothesised that after initial improvement in neonatal sepsis with injectable antibiotics whilst admitted, the same treatment could be safely continued in the outpatient setting to complete the full course. This intervention study was carried out in 66 newborns (0-28 days) recruited at the time of admission with suspected sepsis in the Department of Paediatrics, Centre for Woman and Child Health (CWCH), Dhaka. After investigations, treatment was initiated with injectable antibiotics according to clinical diagnosis and severity. Families who agreed to stay and complete the treatment as inpatient were given the complete course of antibiotics in hospital as IPD group and those who wanted to shorten their stay in hospital, were discharged with injectable antibiotics and follow-up in the outpatient department as OPD group. Data were analysed on 59 neonates, 37 in the OPD and 22 in the IPD group, admitted to hospital between April 2014 and December 2015. There were no readmissions or complications in either group, but one newborn died in the IPD group. Cure rate was 100% in both OPD and IPD groups. Average duration of hospital stay was 3.95±1.76 days and 6.14±2.99 days in the OPD and IPD groups respectively. Treatment cost per patient was 5,823±3,752 Bangladesh Taka (BDT) and 7,082±6,520 BDT in the OPD and IPD groups respectively. Findings of this study suggest that early discharge with injectable antibiotics as an outpatient is a safe and cost effective option for neonatal sepsis.

Intermittent inotropic therapy in an outpatient setting: A cost-effective therapeutic modality in patients with refractory heart failure

1996 ◽  
Vol 132 (4) ◽  
pp. 805-808 ◽  
Author(s):  
Andres L. Marius-Nunez ◽  
Lori Heaney ◽  
Raymond N. Fernandez ◽  
William A. Clark ◽  
Anil Ranganini ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cost Effective ◽  
Outpatient Setting ◽  
Therapeutic Modality ◽  
Inotropic Therapy ◽  
Refractory Heart Failure

scholarly journals Integration of a National E-Theses Online Service with Institutional Repositories

Publications ◽  
2020 ◽  
Vol 8 (2) ◽  
pp. 20
Author(s):  
Vasily Bunakov ◽  
Frances Madden
Keyword(s):  
Query Language ◽  
National Laboratory ◽  
Information Resource ◽  
Online Service ◽  
Institutional Repositories ◽  
Research Outcomes ◽  
Research Facilities ◽  
Large Research ◽  
Integrated Information

We present an information resource prototype that was developed by the FREYA project for the integration of a national e-thesis service and institutional repositories supported by a large national laboratory. The integration allows us to mutually enrich the metadata in the e-thesis service and institutional repositories with new entities and attributes, and can offer novel ways of reasoning over research outcomes that are supported by direct funding and funding-in-kind by large research facilities. The integrated information resource can be presented as a labeled-property graph for its exploration with a declarative query language and visualizations. We emphasize the role of persistent identifiers (PIDs), including for entities that are currently not necessarily or not consistently assigned PIDs.

New pole figure calculation software:2DiffCalc

2009 ◽  
Vol 42 (4) ◽  
pp. 730-733 ◽  
Author(s):  
Ulf Garbe
Keyword(s):  
Pole Figure ◽  
Peak Position ◽  
Fast Method ◽  
Texture Measurement ◽  
Area Detector ◽  
Pole Figures ◽  
Diffraction Patterns ◽  
Research Facilities ◽  
Standard Software ◽  
Large Research

At neutron and synchrotron radiation research facilities, texture measurement with area detectors leads to a large amount of data. During the measurement time, a preliminary analysis of the acquired diffraction patterns is essential. A first view of the resulting pole figures affords the opportunity to evaluate the measurement and to change the instrument parameters accordingly. At a large research facility, the instrument is built with unique adaptations to different scientific cases. At this stage, there is no commercial standard software available to analyse the measured raw data. For these purposes, new software,2DiffCalc, was developed to provide a fast method for pole figure calculation. This software is able to determine the pole figure intensities automatically from the measured area-detector images.2DiffCalccalculates the integral intensities, peak position and width in combination with the pole figure angles.

Is Outpatient Laparoscopic Cholecystectomy Safe and Cost-effective?

1999 ◽  
Vol 90 (6) ◽  
pp. 1746-1755. ◽  
Author(s):  
Lee A. Fleisher ◽  
Kelvin Yee ◽  
Keith D Lillemoe ◽  
Mark A. Talamini ◽  
Charles J. Yeo ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Outpatient Surgery ◽  
Operating Time ◽  
Cost Savings ◽  
Postoperative Nausea And Vomiting ◽  
Cost Effective ◽  
Outpatient Setting ◽  
Postanesthesia Care Unit ◽  
Outpatient Basis ◽  
Home Setting

Background There is increasing pressure to perform traditional inpatient surgical procedures in an outpatient setting. The aim of the current trial was to determine the safety and cost savings of performing laparoscopic cholecystectomy in an outpatient setting using a "mock" outpatient setting. Methods Patients who were scheduled for laparoscopic cholecystectomy by four attending surgeons and for whom operating time was available in the outpatient center were studied. All patients received a standardized anesthetic, including ondansetron, and were discharged from the outpatient postanesthesia care unit if appropriate. At discharge, all patients were admitted to a clinical research center where they were observed in a "mock home" setting and monitored for complications that would have necessitated readmission. A decision analysis was created assuming all patients underwent outpatient surgery with either direct admission or discharge to home and readmission if complications developed. Results Of 99 patients who were enrolled in this study, 96 patients would have met the discharge criteria for home. No major complications were observed in these 96 patients. Eleven patients experienced postoperative nausea and vomiting, 3 of whom required an additional 24 h of hospital observation. In the decision model, the optimal strategy would be to perform the procedure on an outpatient basis and readmit patients only for complications, with an average baseline cost savings of $742/patient. Conclusions The results show that outpatient laparoscopic cholecystectomy is safe and cost-effective in selected patients, and that the mock home setting provides a means of studying the safety of transition of care.

scholarly journals Is Outpatient Thyroid Surgery for Everyone?

2017 ◽  
Vol 10 ◽  
pp. 117955061772442 ◽  
Author(s):  
Dale Butler ◽  
Sarah Oltmann
Keyword(s):  
Patient Outcomes ◽  
Postoperative Bleeding ◽  
Hospital Setting ◽  
Cost Effective ◽  
High Volume ◽  
Outpatient Setting ◽  
Current Trends ◽  
Surgeon Experience ◽  
Reduced Costs ◽  
Inpatient Basis

Thyroidectomy is a common surgical procedure. Traditionally, surgeons have performed thyroidectomy on an inpatient basis. However, consistent with current trends in surgery, some practices are transitioning thyroidectomy to an outpatient setting. Although concerns for hypocalcemia and postoperative bleeding exist regardless of surgeon experience, multiple studies demonstrate that outpatient thyroidectomy is safe in the hands of high-volume surgeons. Indeed, experienced thyroid surgeons who perform thyroidectomy in an outpatient setting experience excellent patient outcomes and reduced costs. However, outpatient thyroidectomy may not be suitable for all surgeons, hospitals, or patients. When evaluating whether to implement an outpatient thyroid program, a practice should consider a number of important factors including the team performing the procedure, the hospital, and the patient. With the appropriate staff education and experience, hospital setting, and patient selection, practices in a multitude of settings can successfully develop a safe, cost-effective outpatient thyroid program.

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