scholarly journals Treatment of Rapid Progression of Myopia: Case Series and Literature Review

2021 ◽  
pp. 875-881
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Itay Lavy ◽  
Eran Pras ◽  
...  
Keyword(s):  
Contact Lens ◽  
Axial Length ◽  
Contact Lenses ◽  
Case Series ◽  
Rapid Progression ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Current Case ◽  
Soft Contact Lens

This retrospective case series demonstrates the combination of 0.05% atropine with MiSight<sup>®</sup> 1 day (Cooper vision, Sar Ramon, CA, USA) in rapid progression of myopia of 4 children. MiSight<sup>®</sup> 1 day is a peripheral defocus, center-distance soft contact lens and is effective at controlling moderate progression of myopia during the course of 1 year. The current case series included 2 females and 2 males with an average age of 9.68 ± 0.26 years and an average axial length of 24.81 ± 0.92 mm. Their myopic progression during the previous year was −1.45 ± 0.27 D. The children had not attempted any myopia control thus far. This relatively high increase prompted a combination treatment of daily instillation of 0.05% atropine and MiSight, a daily replacement soft contact lens. Cycloplegic refraction and a slit-lamp evaluation were performed every 6 months to confirm no adverse reactions or staining was present. The 8-item contact lens dry eye questionnaire (CLDEQ-8) score of these children was 10.66 ± 1.52. The average myopia progression at the end of 1 year decreased to −0.41 ± 0.11 D, and the average axial length increase was 0.28 ± 0.08 mm. To the best of the authors’ knowledge, this is the first published study showing a combination of 0.05% atropine and peripheral defocus soft contact lenses indicating efficacy at controlling moderate myopia progression.

scholarly journals Myopia Control with Combination Low-Dose Atropine and Peripheral Defocus Soft Contact Lenses: A Case Series

2021 ◽  
pp. 548-554
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Yair Morad
Keyword(s):  
Low Dose ◽  
Contact Lenses ◽  
Case Series ◽  
Concentric Circle ◽  
Retrospective Case ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lenses ◽  
Center Distance ◽  
Myopia Control

The goal of this retrospective case series is to demonstrate the effectivity of combination low-dose atropine therapy with peripheral defocus, double concentric circle design with a center distance soft contact lenses at controlling myopia progression over 1 year of treatment. Included in this series are 3 female children aged 8–10 years with progressing myopia averaging −4.37 ± 0.88 D at the beginning of treatment. Their average annual myopic progression during the 3 years prior to therapy was 1.12 ± 0.75 D. They had not attempted any myopia control treatments prior to this therapy. The children were treated with a combination of 0.01% atropine therapy with spherical peripheral defocus daily replacement soft lenses MiSight<sup>®</sup> 1 day (Cooper Vision, Phoenix, AZ, USA). They underwent cycloplegic refraction, and a slit-lamp evaluation every 6 months which confirmed no adverse reactions or staining was present. Each of the 3 children exhibited an average of 0.25 ± 0.25 D of myopia progression at the end of 1 year of treatment. To the best of the authors’ knowledge, this is the first published study exhibiting that combining low-dose atropine and peripheral defocus soft contact lenses is effective at controlling children’s moderate to severe myopia progression during 1 year of therapy.

scholarly journals A 3-year Randomized Clinical Trial of MiSight Lenses for Slowing Myopia Progression

The Eye ◽  
2020 ◽  
Vol 22 (4(132)) ◽  
pp. 11-28
Author(s):  
P. Chamberlain ◽  
Sofia C. Peixoto-de-Matos ◽  
N. S. Logan ◽  
Ch. Ngo ◽  
D. Jones ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Contact Lens ◽  
Axial Length ◽  
Test Group ◽  
Control Group ◽  
Spherical Equivalent ◽  
Soft Contact ◽  
Myopia Progression ◽  
Soft Contact Lens ◽  
Spherical Equivalent Refraction

Significance. Results of this randomized, double-masked clinical trial demonstrate the effectiveness of the MiSight soft contact lens in slowing myopia progression over multiple years.Purpose. The purpose of this study was to quantify the effectiveness of MiSight daily disposable soft contact lens in slowing the progression of juvenile-onset myopia.Methods. Myopic children (spherical equivalent refraction, −0.75 to −4.00 D; astigmatism, < 1.00 D) aged 8 to 12 years with no prior contact lens experience were enrolled in a 3-year, double-masked, randomized clinical trial at four investigational sites in four countries. Subjects in each group were matched for age, sex, and ethnicity and were randomized to either a MiSight®1 day contact lens (test) or Proclear®1 day (control; omafilcon A) and worn on a daily disposable basis. Primary outcome measures were the change in cycloplegic spherical equivalent refraction and axial length.Results. Of the subjects enrolled, 75.5% (109/144) completed the clinical trial (53 test, 56 control). Unadjusted change in spherical equivalent refraction was −0.73 D (59%) less in the test group than in the control group (−0.51 ± 0.64 vs. –1.24 ± 0.61 D, P < 0.001). Mean change in axial length was 0.32 mm (52%) less in the test group than in the control group (0.30 ± 0.27 vs. 0.62 ± 0.30 mm, P < 0.001). Changes in spherical equivalent refraction and axial length were highly correlated (r = −0.90, P < .001). Over the course of the study, there were no cases of serious ocular adverse events reported. Four asymptomatic corneal infiltrative (one test, three control) events were observed at scheduled study visits.Conclusions. Results of this clinical trial demonstrate the effectiveness of the MiSight daily disposable soft contact lens in slowing change in spherical equivalent refraction and axial length.

scholarly journals STUDY OF THE OPTICAL POWER OF NANOPHOTONIC SOFT CONTACT LENSES BASED ON POLY (2- HYDROXYETHYL METHACRYLATE) AND FULLERENE

2014 ◽  
Vol 5 (1) ◽  
Author(s):  
Aleksandra Debeljković Mitrović ◽  
Dragomir Stamenković ◽  
Manuel Conte ◽  
Božica Bojović ◽  
Spomenko Mihajlović
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Measurement Techniques ◽  
Optical Power ◽  
Soft Contact ◽  
Standard Material ◽  
Soft Contact Lenses ◽  
Soft Contact Lens ◽  
Power Cylinder

In this paper results of comparative study of the optical power of soft contact lenses (SCL) made of standard material for SCL and nanophotonic materials with different measurement techniques used for the final contact lens controllers are presented. Three types of nanophotonic soft contact lenses were made of standard polymacon material (Soleko SP38TM) incorporated with fullerene C60, fullerol C60(OH)24 and fullerene metformin hydroxylate C60(OH)12(OC4N5H10)12. For the purposes of material characterization for potential application as soft contact lenses, the optical properties of the soft contact lenses were measured by Rotlex and Nidek device. With Rotlex device the following optical results were obtained: optical power and map of defects, while with the Nidek device: optical power, cylinder power and cylinder axis. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is same to the nominal value, while this was not the case for the standard soft contact lens. Also, the quality of the nanophotonic soft contact lens is better than the standard one. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.

scholarly journals Myopia Progression During Three Years of Soft Contact Lens Wear

2009 ◽  
Vol 86 (10) ◽  
pp. 1150-1153 ◽  
Author(s):  
Adam Blacker ◽  
G Lynn Mitchell ◽  
Mark A. Bullimore ◽  
Bill Long ◽  
Joseph T. Barr ◽  
...  
Keyword(s):  
Contact Lens ◽  
Soft Contact ◽  
Myopia Progression ◽  
Contact Lens Wear ◽  
Soft Contact Lens ◽  
Lens Wear

scholarly journals Characterization of nanophotonic soft contact lenses based on poly (2-hydroxyethyl methacrylate) and fullerene

2013 ◽  
Vol 67 (6) ◽  
pp. 861-870 ◽  
Author(s):  
Aleksandra Debeljkovic ◽  
Lidija Matija ◽  
Djuro Koruga
Keyword(s):  
Contact Lens ◽  
Near Infrared ◽  
Contact Lenses ◽  
Base Material ◽  
Optical Power ◽  
Sem Analysis ◽  
Hydroxyethyl Methacrylate ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Soft Contact Lens

This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic materials (SL38-A) for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy). The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia) for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.

Investigation of Lubrication Characteristics for a Soft Contact Lens

2019 ◽  
Vol 823 ◽  
pp. 105-109
Author(s):  
Hung Jung Tsai ◽  
Jeng Haur Horng ◽  
Chung Ming Tan
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Hydrodynamic Lubrication ◽  
Tear Film ◽  
Hydrodynamic Pressure ◽  
Slider Bearing ◽  
Soft Contact ◽  
Soft Contact Lens ◽  
Lubrication Characteristics

It is popular to wear the contact lens nowadays. Also, the output value of the contact lens is estimated more than 4 billion NT dollar every year. Because the phenomena of the contact lenses are very complicated, the relevant mechanisms are not well understood. Thus, the security of contact lens needs to be further investigated. In the lubricated mechanism of the contact lens, there is a layer of tear between the contact lens and cornea. The contact lens’ behavior is akin to that of a slider bearing. The lens represents the slider, the eye plays the role of the stationary pad, and the tear film is the lubricant. Hence, hydrodynamics and contact mechanisms of a contact lens are quite a fascinating subject that is relevant to the science of tribology. In the paper, the lubrication mechanisms include the partial hydrodynamic lubrication (contact lens roughness), contact mechanics and Newtonian fluid mechanics have been established. The parameters of roughness, flow factor, tear film geometry, and hydrodynamic pressure distribution are discussed. The developed technology increases the safety of contact lens.

The effect of soft contact lenses with L-Menthol to enhance soft contact lens end of the day comfort

2021 ◽  
Vol 44 (1) ◽  
pp. 18
Author(s):  
Ruby Chiang ◽  
Rebecca Gao ◽  
Terry Chang ◽  
Jerry Chen ◽  
George Hsu
Keyword(s):  
Contact Lens ◽  
Contact Lenses ◽  
Soft Contact ◽  
Soft Contact Lenses ◽  
Soft Contact Lens
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