Sustained Complete Remission in Multi-Relapsed Primary CNS Lymphoma Treated with Ibrutinib Monotherapy: A Case Report
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Primary CNS lymphoma (PCNSL) is a highly aggressive malignant disease with a high recurrence rate and a poor prognosis. We present the case of a 71-year-old woman diagnosed with PCNSL in June 2010. After 3 relapses and intensive treatment with multiple chemotherapy regimens and whole-brain radiotherapy, she received off-label treatment with the Bruton tyrosine kinase inhibitor ibrutinib, responded well, achieved a complete remission, and is progression-free for now >3 years.
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2004 ◽
Vol 22
(14_suppl)
◽
pp. 1518-1518
Keyword(s):
2004 ◽
Vol 22
(14_suppl)
◽
pp. 1518-1518
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Keyword(s):
2013 ◽
Vol 31
(31)
◽
pp. 3971-3979
◽
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2010 ◽
Vol 11
(11)
◽
pp. 1011-1012
◽
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