Peripheral arterial disease and Virchow’s triad

2009 ◽  
Vol 101 (06) ◽  
pp. 1032-1040 ◽  
Author(s):  
Philip Bennett ◽  
Stanley Silverman ◽  
Paramjit Gill ◽  
Gregory Lip
Keyword(s):  
Risk Factors ◽  
Peripheral Arterial Disease ◽  
Vessel Wall ◽  
Clinical Utility ◽  
Thrombus Formation ◽  
Arterial Disease ◽  
Blood Constituents ◽  
Global Health Care ◽  
Considerable Morbidity ◽  
Peripheral Arterial

SummaryPeripheral arterial disease (PAD) is an important global health-care problem associated with considerable morbidity and mortality. This disease is an important manifestation of atherosclerosis and the pathophysiological processes involved in its development, progression and complications are atherothrombosis and thromboembolism. Over 150 years ago, Virchow described a triad of abnormalities (abnormal blood flow, abnormal vessel wall and abnormal blood constituents) associated with thrombus formation (thrombogenesis). An improvement in biochemical techniques has allowed quantification of various components of Virchow’s triad, and as a consequence, there has been increasing interest in the measurement of such biomarkers in understanding the development and progression of PAD, as well as its symptomatic complications. This review discusses quantifiable components of Virchow’s triad that have been associated with PAD and their clinical utility as risk factors for PAD.

Vessel Wall Calcifications at Multi–Detector Row CT Angiography in Patients with Peripheral Arterial Disease: Effect on Clinical Utility and Clinical Predictors

Radiology ◽  
2006 ◽  
Vol 241 (2) ◽  
pp. 603-608 ◽  
Author(s):  
Rody Ouwendijk ◽  
Marc C. J. M. Kock ◽  
Lukas C. van Dijk ◽  
Marc R. H. M. van Sambeek ◽  
Theo Stijnen ◽  
...  
Keyword(s):  
Peripheral Arterial Disease ◽  
Ct Angiography ◽  
Vessel Wall ◽  
Clinical Utility ◽  
Arterial Disease ◽  
Clinical Predictors ◽  
Disease Effect ◽  
Peripheral Arterial

Endothelial reactivity and cardiac risk factors in older patients with peripheral arterial disease

1999 ◽  
Vol 83 (5) ◽  
pp. 754-758 ◽  
Author(s):  
Alberto Rafael Yataco ◽  
Mary Concepta Corretti ◽  
Andrew William Gardner ◽  
Christopher Joseph Womack ◽  
Leslie Ira Katzel
Keyword(s):  
Risk Factors ◽  
Peripheral Arterial Disease ◽  
Older Patients ◽  
Arterial Disease ◽  
Cardiac Risk ◽  
Cardiac Risk Factors ◽  
Peripheral Arterial

scholarly journals Correlation between Peripheral Arterial Disease and Coronary Artery Disease in Bangladeshi Population- A Five Years Retrospective Study

2017 ◽  
Vol 11 (2) ◽  
pp. 79-84
Author(s):  
Syed Dawood Md Taimur ◽  
Mashhud Zia Chowdhury ◽  
Md Enamul Hakim
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Peripheral Arterial Disease ◽  
Positive Family History ◽  
Arterial Disease ◽  
Coronary Angiogram ◽  
Vessel Disease ◽  
Artery Disease ◽  
Peripheral Arterial

Background: Peripheral arterial disease (PAD) is under diagnosed in primary care practices, yet the extent of unrecognized PAD in patients with coronary artery disease (CAD) is unknown.Objective: To assess the prevalence of previously unrecognized PAD in patients undergoing coronary angiogram and to determine the relationship between presence of PAD and severity of CAD. Material &Methods: This five years retrospective study was conducted at invasive lab of the department of Cardiology, Ibrahim Cardiac Hospital & Research Institute, Dhaka, Bangladesh from January 2010 to December 2014. Total 77 patients were included in this study. Study variables were age, sex, risk factors like hypertension, diabetes mellitus, dyslipidaemia, smoking habit and positive family history for ischemic heart disease, severity of coronary artery and peripheral artery disease.Results: Mean age was 56.83±13.64 years, Male mean age was 53.98±15.08 years and female mean age was 54.5±1.73years. Hypertension were detected in 55.8%, diabetes in 87%, dyslipidaemia in 81.8%, smoking habits in 88.3% and 58.4% had positive family history. After catheterization 88.3% had peripheral arterial disease and 71.4% had coronary artery disease. Out of 77 patients 52 had both coronary and peripheral arterial disease which was statistically significant (p<.014). Coronary angiogram revealed 28.6% (22) patients had triple vessel disease, 23.3% (18) had single vessel disease, 19.5% (15) had double vessel disease and 28.6% (22) were normal coronary arteries. Peripheral angiogram revealed 51.9% had superficial femoral artery disease, 24.7% had anterior tibial artery disease, 26% had posterior tibial artery disease, 15.6% had common iliac artery and common femoral artery disease and 2.6% had renal artery disease.Conclusion: There is a strong and definite correlation between coronary and peripheral arterial disease. We found that cardiovascular risk factors were in fact risk factors for both PAD and CAD.University Heart Journal Vol. 11, No. 2, July 2015; 79-84

Sign in / Sign up

Export Citation Format

Share Document